Abstract: The invention relates to uricase-drug conjugates comprising a uricase with a linker-drug attached to either the protein core or other moiety attached to the protein core. The pegylated uricase-drug conjugates mitigate the formation of anti-drug antibodies to improve the therapeutic efficacy of enzymes such as uricase. The uricase-drug conjugate may be administered subcutaneously or intravenously.

Abstract: Provided are a group CD24 binding proteins and uses thereof. Specifically provided is a group of antigen binding proteins, wherein cells expressing the antigen binding protein can have cytotoxicity and safety. Also provided is a use of the antigen binding protein in the preparation of a medication.

Abstract: A method may include detecting, at a first client device engaged in a web conference session with a second client device, a selection of a user interface element associated with a first input mode in which at least a portion of content captured at the first client device is excluded from being shared with the second client device. In response to the selection of the user interface element, the first input mode may be activated at the first client device by disabling multiple input devices associated with the first client device such that at least the portion of the content captured at the first client device is excluded from being shared with the second client device. Meanwhile, when a second input node is activated at the first client device, the content captured at the first client device may be shared with the second client device without restrictions.

Abstract: The invention relates to the field of biomedicine, in particular to a T cell co-expressing CXCR2 and a Synthetic T-Cell Receptor and Antigen Receptor (STAR) against GPC3, and uses thereof.

Abstract: A method may include detecting, at a first client device engaged in a web conference session with a second client device, a selection of a user interface element associated with a first input mode in which at least a portion of content captured at the first client device is excluded from being shared with the second client device. In response to the selection of the user interface element, the first input mode may be activated at the first client device by disabling multiple input devices associated with the first client device such that at least the portion of the content captured at the first client device is excluded from being shared with the second client device. Meanwhile, when a second input node is activated at the first client device, the content captured at the first client device may be shared with the second client device without restrictions.

Abstract: Methods, apparatus, and computer-readable media for providing a content protection service in electronic messaging systems are described herein. The content protection service may be engaged by an electronic messaging sending device by receiving a protection action. Or it may be engaged by an electronic messaging server by checking a protection policy. The content protection service may be engaged to alias, and/or conceal an original content item. When aliasing, a modified electronic message content comprises aliased content and omits the original content. When concealing, a modified electronic message content comprises a concealment and omits the original content. When aliasing and concealing, a modified electronic message content comprises a concealment and omits both the aliased and original contents.

Abstract: A method of assessing the health of each oocyte or embryo of a mammal from a plurality of oocytes/embryos of the mammal is provided. The method comprises the steps of: measuring gap junctional coupling strength or connexin43 expression of follicular cells associated with each oocyte; and identifying the gap junctional coupling strength/connexin43 expression of follicular cells associated with each oocyte, wherein the greater the coupling strength/connexin43 expression of follicular cells associated with an oocyte relative to the coupling strength/connexin43 expression of follicular cells associated with each other oocyte, the healthier the oocyte and the embryo resulting from that oocyte. Kits for conducting these methods are also provided.