Abstract: A dry powder inhaler includes a powder storage element configured to hold a powdered medicament and an inlet channel receives powdered medicament from the powder storage element that is entrained in an airflow. The inlet channel has a first diameter and defines an opening. The inhaler includes a dispersion chamber that receives the airflow and the powdered medicament from the opening. The dispersion chamber has a second diameter. The inhaler includes an actuator housed within the dispersion chamber. The actuator oscillates within the dispersion chamber when exposed to the airflow to deaggregate the powdered medicament entrained by the airflow passing through the dispersion chamber. A ratio between the first diameter and the second diameter is between about 0.40 and 0.60 such that an audible sound is produced as the actuator oscillates. The inhaler includes an outlet channel through which the airflow and powdered medicament exit the inhaler.

Abstract: Provided is a method for calibrating a deformation pressure of a large-volume press. The method for calibrating the deformation pressure of the large-volume press includes: depositing a conductive layer onto a surface of a bevel plug to obtain a conductive bevel plug; assembling the conductive bevel plug, a molybdenum pillar, a magnesium oxide tube, a magnesium oxide sample chamber, a magnesium oxide octahedron and a calibration standard material, placing a resulting system in the large-volume press, and subjecting the resulting system to a large-volume press pressure correction experiment.

Abstract: A meeting robot method and system is provided. In one embodiment, a meeting substitute system includes processing circuitry configured to cause the meeting substitute system to obtain information related to a meeting request, the information associated with a teleconference meeting and the information including a date and a time for the teleconference meeting; as a result of a trigger, automatically: join the teleconference meeting at the date and the time; and during the joined teleconference meeting, capturing a set of meeting data for the teleconference meeting, the captured set of meeting data comprising at least one of a video recording and an audio recording of the teleconference meeting and a speech-to-text translation; and generate a meeting summary based at least in part on the captured set of meeting data for the teleconference meeting.

Abstract: Disclosed are a method and a device for identifying full-section excavation parameters of large-section tunnel with broken surrounding rock, which is capable of solving the problem of inaccurate arrangement of blasting hole points in tunnel excavation engineering, including following steps: establishing a three-dimensional finite element model based on a blasting section design of a tunnel; performing a simulation with the three-dimensional finite element model based on blasting design parameters to obtain blasting quality parameters; selecting a group closest to a preset quality parameter from multiple groups of the blasting design parameters as target blasting design parameters, wherein the preset quality parameter is an acceptance grade standard of the tunnel; obtaining first thermal imaging information of a first hot spot of a surface to be blasted; calibrating actual hole spacing parameters based on the first thermal imaging information and the target blasting design parameters.

Abstract: A display substrate is provided to include: a first base substrate including a sealing region and a display port region, wherein at least one first connection region and at least one second connection region are in the display port region, a first overlapping region is formed between the second and first connection regions; first and second connection terminals in the first and second connection regions, respectively; and a planarization layer including at least one first trench and at least one second trench corresponding to the first and second connection regions therein, respectively; orthographic projections of bottoms of first and second trenches on the first base substrate cover corresponding first and second connection regions, respectively; the planarization layer includes: a first pattern corresponding to the first overlapping region; orthographic projections of the first pattern and its corresponding first overlapping region on the first base substrate overlap with each other.

Abstract: Monitoring Electrical Systems with Multiple Ground Connection Points A method for monitoring an electrical system having multiple electrical ground connection points. The method comprises receiving reflectometry data that has been generated by performing time domain reflectometry on the electrical system, the time domain reflectometry being performed during a measurement time period. The method further comprises: determining a measured waveform from the reflectometry data, the measured waveform indicative of a measured state of the system during the measurement time period; obtaining a predetermined baseline waveform indicative of a baseline state of the system during a calibration time period; generating a difference waveform based on the measured waveform and the baseline waveform; and analysing the difference waveform to determine if there is a change of state in the electrical system between the calibration period and measurement period.

Abstract: Certain aspects of the present disclosure provide techniques for supporting multiple types of random access occasions. A method that may be performed by a user equipment (UE) includes receiving, from a base station (BS), an indication of at least two types of random access occasions (ROs) including a first RO type and a second RO type for communicating in a first coverage area of the BS as part of a random access process for the UE to establish a connection with the BS in the first coverage area. The method further includes transmitting, to the BS, a preamble on an RO of one of the first RO type or the second RO type, wherein a preamble format of the preamble is based on whether the RO is of the first RO type or the second RO type.

Abstract: Provided in the invention are a catalyst for preparing phosgene and a preparation method therefor, and a method for the preparation of phosgene and the comprehensive utilization of energy thereof. The preparation method comprises the following steps: 1) stirring and soaking activated carbon in a modifying solution, then adding dimethyltin dichloride and chromium oxide powders and carrying out a reaction, and then adding a nickel oxide fine powder and ultrasonically oscillating same to prepare a pre-modified activated carbon; 2) drying the pre-modified activated carbon; and 3) heating and calcinating the dried pre-modified activated carbon from step 2) to prepare the catalyst.

Abstract: Disclosed is a method for preparing a product for treating scald infection caused by Pseudomonas aeruginosa. The product includes a ferrous sulfate hydrogel, the scald is a deep second-degree scald or a third-degree scald, and a preparation process of the ferrous sulfate hydrogel includes: S1, obtaining a mixed solution by dissolving ferrous sulfate and vitamin C at a concentration ratio of 1:1 in sterile ultrapure water, heating the mixed solution to 50° C., and a concentration of the ferrous sulfate in the mixed solution being 2 mM, and S2, under a condition of heating, continuing to add sodium alginate powder whose mass constitutes 3.5% of a total mass of the mixed solution, stirring until the sodium alginate powder is dissolved and forming a stable colloid, and obtaining 2 mM of the ferrous sulfate hydrogel.

Abstract: Processes for producing reduced coenzyme Q10 (CoQ10) are provided. The processes may include preparing a reaction mixture, which includes oxidized CoQ10, a reductase, a supplement coenzyme, a coenzyme regeneration enzyme, and a substrate of the coenzyme regeneration enzyme, and providing a condition so that components of the reaction mixture react to produce the reduced CoQ10.

Abstract: A display panel includes a substrate, and a plurality of first pixel circuits, a plurality of first light-emitting devices and a plurality of first light-shielding portions that are located in a functional device setting region. The plurality of first light-emitting devices are disposed on a side of the plurality of first pixel circuits away from the substrate. A first light-emitting device includes a first electrode electrically connected to a first pixel circuit. The plurality of first light-shielding portions are arranged at intervals on a side of the plurality of first light-emitting devices away from the substrate. Each first light-shielding portion is provided with a first opening therein, and each first opening corresponds to a single first light-emitting device. An orthographic projection of a first portion of the first pixel circuit on the substrate is located within an orthographic projection of a first light-shielding portion on the substrate.

Abstract: A pharmaceutical combination comprising (i) a first component selected from an immune effector cell (e.g., a T cell and an NK cell) expressing a molecular switch-regulated CAR polypeptide, a nucleic acid molecule encoding the CAR polypeptide, a vector comprising the nucleic acid molecule, and any combination thereof; and (ii) a second component, which is an antibody that contains a P329G mutation and specifically binds to a B-cell maturation antigen (BCMA) protein. The present invention also relates to a kit comprising the pharmaceutical combination, and the use of the pharmaceutical combination in the treatment of BCMA-related diseases in a subject.

Abstract: Disclosed are techniques for positioning. A receiver measures a time of arrival (ToA) of a positioning reference signal (PRS) transmission of a first PRS sequence transmitted by a first transmitter, measures a ToA of a PRS transmission of a second PRS sequence transmitted by a second transmitter, and determines an observed time difference of arrival (OTDOA) as a difference between the ToA of the PRS transmission of the first PRS sequence and the ToA of the PRS transmission of the second PRS sequence, wherein the OTDOA is less than half a maximum differential delay expected between the PRS transmission of the first PRS sequence and the PRS transmission of the second PRS sequence, and wherein a repetition duration of the first PRS sequence and the second PRS sequence is greater than 10 milliseconds (ms) and at least twice the maximum differential delay.

Abstract: A method of interfacing a discrete digital workshop information system is provided, where the information system includes mutual integration among product lifecycle management (PLM), enterprise resource planning (ERP), a manufacturing execution system (MES), an energy management system (EMS), and a warehouse management system (WMS) of a finished product. A method of interfacing based on a data dictionary fusing different function datasets is proposed to solve the problems of a current discrete industry information system, such as single in function, a small amount of integrated information, a large number of “information islands” existing, incapable of achieving full-process informatization management and control, difficulty in product quality tracing and the like. By the method, it is possible to realize flexible production in a discrete manufacturing industry, precise management and control of a production process, significant improvement in product quality and significant reduction in operating costs.

Abstract: Provided is an information system and an information collection method that are capable of acquiring desired site data while preventing an increase in cost. A link logic definition unit 17 holds a link logic that is definition information defining a correspondence relation between an item value of the site data and a reference value that is an external value of transaction data used for acquiring the item value. A link logic data acquisition unit 18 acquires the item value of the site data by using the link logic.

Abstract: Provided are an antibody having an improved affinity for specifically binding to BCMA, an antibody further comprising a P329G mutation, and a conjugate, a fusion, a bispecific antibody or a pharmaceutical composition comprising the antibody. In addition, further provided are a nucleic acid encoding the antibody, a host cell comprising the nucleic acid, and a method for preparing the antibody. The present invention also relates to the therapeutic and diagnostic use of the antibody binding to BCMA.

Abstract: The present disclosure provides a method, apparatus, medium and device for extracting a river drying-up region and frequency, and belongs to the technical field of remote sensing. The method for extracting a river drying-up region and frequency can be applied to efficiently acquiring river drying-up information for a long time within the large spatial region. With the inverse normalized difference water index (iNDWI) and the maximum value composite (MVC) method for the remote sensing images, the present disclosure omits the troublesome step of separately extracting a river range for each image in the conventional method. In addition, the present disclosure quickly obtains the drying-up frequency by counting the total number of available images and the number of non-water images at the same pixel position, and yields a greater efficiency for extracting the river drying-up region and frequency.

Abstract: The present disclosure provides a display device, a splicing display device, the display device includes: a display panel including a display region and a non-display region surrounding the display region, the non-display region including a bonding region; a backlight module disposed opposite to the display panel; a tape layer located on a peripheral side of the display panel and the backlight module, and an orthographic projection of the tape layer on a plane where the display device is located is not overlapped with an orthographic projection of the display panel on the plane where the display device is located.

Abstract: The present invention provides a mono-p-toluenesulfonate of (S)-(2-((5-chloro-2-((7-(pyrrolidin-1-yl)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl)amino)pyrimidin-4-yl)amino)-5-(methoxymethyl)phenyl)dimethyl phosphine oxide, and a hydrate and a crystal form thereof. The crystal form of p-toluenesulfonate has a good stability, is easy to process, and has a high solubility.

Abstract: The application discloses a system and method for centrifugal intrusion of molten metal into porous media and then solidification positioning, including: test cups, used for placing test medium and molten metal intrusion; a rotor block, used for mounting the test cups, where one end of each test cup for placing the test medium is far away from the rotor block; a constant temperature oil bath preheating device, used for preheating the test cups and the rotor block; a centrifugal device, internally provided with the rotor block, used for performing a centrifugal operation on the test cups, where the test cups and the rotor block are installed inside the centrifugal device after being preheated; and an infrared heating and compression refrigerating device, arranged inside the centrifugal device, used for controlling a temperature of the test cups.