Patents by Inventor Dan Xu

Dan Xu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220144821
    Abstract: The present invention discloses an AKT inhibitor, and specifically relates to a compound represented by formula I or a pharmaceutically acceptable salt thereof. The present invention further provides a preparation method thereof, and the use thereof in prevention and/or treatment of a disease mediated by AKT protein kinase.
    Type: Application
    Filed: January 22, 2020
    Publication date: May 12, 2022
    Inventors: Changyou Ma, He Tian, Jie An, Jianliang Zhao, Donghui Chen, Jian Wu, Dan Xu, Chunxia Zhu, Zhoushan Tian
  • Publication number: 20220143034
    Abstract: Novel dry powder compositions comprising and methods relating thereto are provided. The dry powder compositions comprise PDE5 inhibitors, such as vardenafil, or pharmaceutically acceptable salts or esters thereof. The dry powder compositions may optionally include an carrier/excipient. The concentration of active agent may be at least about 2% by weight. Methods of aerosolizing the dry powder compositions and using them to treat various diseases are also disclosed.
    Type: Application
    Filed: January 20, 2022
    Publication date: May 12, 2022
    Applicant: Respira Therapeutics, Inc.
    Inventors: Zhen Xu, Hugh Smyth, Aileen Gibbons, Revati Shreeniwas, Pravin Soni, Dan Deaton, James Hannon, Stephen Lermer, Robert Curtis, Martin J. Donovan
  • Patent number: 11291691
    Abstract: Methods are provided for producing a population of hepatocyte-like cells (iHeps) from a population of adipocyte-derived stem cells (ASCs). Aspects of the methods include placing a population of ASCs into a three dimensional culture (e.g., hanging drop suspension culture, high density culture, spinner flask culture, microcarrier culture, etc.), and contacting the cells with a first and second culture medium. Also provided are methods of treating an individual, which include producing a population of iHeps from a population of ASCs, and administering an effective number of iHeps into the individual. Kits for practicing the methods are also described herein.
    Type: Grant
    Filed: May 8, 2018
    Date of Patent: April 5, 2022
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Gary Peltz, Dan Xu
  • Publication number: 20220056479
    Abstract: Disclosed is a method for delivering a gene into target cells, wherein immune cells are used as a vector for virus packaging and transportation to complete the delivery of biomacromolecules among cells, and thus change original characteristics of the target cells or generate new characteristics in the target cells. The gene delivery system, on one hand, can kill target cells such as tumor cells by utilizing the specificity of immune cells; and on the other hand, can modify genes of cells in a lesion by gene delivery to target cells, to directly kill the target cells.
    Type: Application
    Filed: December 16, 2019
    Publication date: February 24, 2022
    Inventors: Pei Wang, Luying Jia, Yanni Lin, Zhijie Niu, Dan Xu, Jiaolong Fang, Hui Yuan, Ting Liu
  • Publication number: 20220054365
    Abstract: Flexible, dissolvable, porous solid sheet articles which include direct-added microcapsules therein for delivering a benefit agent and a process for making such solid sheet articles.
    Type: Application
    Filed: August 5, 2021
    Publication date: February 24, 2022
    Inventors: Dan XU, Carl David MAC NAMARA, Xiao TIAN, HongSing TAN, Robert Wayne GLENN, JR.
  • Patent number: 11247068
    Abstract: The invention provides a light therapy device for providing therapeutic treatment to a user's body, wherein the user may be a person or an animal. The device is using a light projection method for treating the body problems and/or skin disorders. Further, the device is having a rotatable assembly that automatically follows the movement of the desired area of the body needs to be treated. The device uses artificial intelligence, machine learning, localization modules, object detection module, image processing module, and 3D-mapping to automatically identify and treating the desired area of the body. Furthermore, the user can manually identify, select and prioritize desired treatment portion and can select the type of treatment required.
    Type: Grant
    Filed: October 2, 2018
    Date of Patent: February 15, 2022
    Assignee: ShenZhen Kaiyan Medical Equipment Co, LTD
    Inventors: Alain Dijkstra, Jonathan James Knight, Jooeun Kim, Yong Zhang, Dan Xu
  • Publication number: 20210388105
    Abstract: Provided are anti-CD39 antibodies or antigen-binding fragments thereof, isolated polynucleotides encoding the same, pharmaceutical compositions comprising the same and the uses thereof.
    Type: Application
    Filed: August 26, 2020
    Publication date: December 16, 2021
    Inventors: Yangsheng QIU, Meiling SUN, Roumei XING, Dan XU, Yufei SHI, Jinfeng ZHAO, Qinglin DU, Zhihao WU, Rui GAO, Robert H. ARCH, Hongtao LU
  • Publication number: 20210366558
    Abstract: Apparatus having a string of series-connected memory cells, a plurality of access lines with each access line of the plurality of access lines connected to a control gate of a respective memory cell of the plurality of memory cells, and a controller for access of the string of series-connected memory cells and configured to cause the memory to increase a threshold voltage of a particular memory cell of the string of series-connect memory cells to a voltage level higher than a predetermined pass voltage to be received by a control gate of the particular memory cell during a read operation on the string of series-connected memory cells, and concurrently change a respective data state of each memory cell of a plurality of memory cells of the string of series-connected memory cells.
    Type: Application
    Filed: July 26, 2021
    Publication date: November 25, 2021
    Applicant: MICRON TECHNOLOGY, INC.
    Inventors: Zhengyi Zhang, Dan Xu, Tomoko Ogura Iwasaki
  • Publication number: 20210347908
    Abstract: Provided are anti-SIRP? antibodies or antigen-binding fragments thereof, isolated polynucleotides encoding the same, pharmaceutical compositions comprising the same and the uses thereof.
    Type: Application
    Filed: August 18, 2020
    Publication date: November 11, 2021
    Inventors: Xiaofeng NIU, Jingfeng YU, Jinfeng ZHAO, Fengli WANG, Dan XU, Roumei XING, Zhihao WU, Qinglin DU, Yangsheng QIU, Robert H. ARCH, Hongtao LU
  • Publication number: 20210304029
    Abstract: In an example embodiment, a machine learned model that integrates a generalized linear mixed model (GLMix) non-linear optimization is utilized to jointly perform personalized communications targeting and volume control. The machine learned model may be trained to not only maximize user engagement with a notification generally, such as maximizing the total number of people who view, save, or apply for a job associated with a job listing in the communication, but also trained to maximize an end goal of the notification, such as the total number of people who apply for the job associated with a job listing in the communication.
    Type: Application
    Filed: March 30, 2020
    Publication date: September 30, 2021
    Inventors: Dan Xu, Chunzhe Zhang, Qing Li, Jiuling Wang, Kunal Mukesh Cholera
  • Patent number: 11123572
    Abstract: The present disclosure relates to an eyewear phototherapy device for providing skin cosmetology to the skin surrounding the eyes. The device includes a main spectacle frame having a left supporting member and right supporting member, each including at least one housing assembly extending outward from the each supporting member and facing towards the inner portion of the supporting member. Each of the housing assemblies includes an LED light board, attached to the inner side of the respective housing assembly, which is adapted to emit light energy, a transparent silicone cover attached on the LED light board for protecting direct contact between the LED light board and human skin, a protective element which is adapted to spread the LED emissions around a human eye and provide protection to the human eye from the LED emissions.
    Type: Grant
    Filed: May 4, 2018
    Date of Patent: September 21, 2021
    Inventors: Alain Dijkstra, Jonathan James Knight, Jooeun Kim, Yong Zhang, Dan Xu
  • Publication number: 20210261892
    Abstract: This provides a flexible, porous, dissolvable solid sheet article containing a cationic surfactant.
    Type: Application
    Filed: February 10, 2021
    Publication date: August 26, 2021
    Inventors: Dan XU, Hongsing TAN, Juan YANG, Na HOU, Carl David MAC NAMARA, Yongli PAN
  • Patent number: 11087851
    Abstract: Apparatus having a string of series-connected memory cells comprising a plurality of principal memory cells and a plurality of dummy memory cells might have a controller configured to cause the apparatus to apply a first programming pulse to a particular dummy memory cell of the plurality of dummy memory cells sufficient to increase a threshold voltage of the particular dummy memory cell to a voltage level sufficient to cause the particular dummy memory cell to remain deactivated during a read operation on the string of series-connected memory cells, and to concurrently apply a second programming pulse to each principal memory cell of the plurality of principal memory cell sufficient to increase threshold voltages of at least a portion of the plurality of principal memory cells.
    Type: Grant
    Filed: June 8, 2020
    Date of Patent: August 10, 2021
    Assignee: Micron Technology, Inc.
    Inventors: Zhengyi Zhang, Dan Xu, Tomoko Ogura Iwasaki
  • Publication number: 20210201993
    Abstract: Memory array structures providing for determination of resistive characteristics of access lines might include a first block of memory cells, a second block of memory cells, a first current path between a particular access line of the first block of memory cells and a particular access line of the second block of memory cells, and, optionally, a second current path between the particular access line of the second block of memory cells and a different access line of the first block of memory cells. Methods for determining resistive characteristics of access lines might include connecting the particular access line of the first block of memory cells to a driver, and determining the resistive characteristics in response to a current level through that access line and a voltage level of that access line.
    Type: Application
    Filed: September 3, 2020
    Publication date: July 1, 2021
    Applicant: MICRON TECHNOLOGY, INC.
    Inventors: Dan Xu, Jun Xu, Erwin E. Yu, Paolo Tessariol, Tomoko Ogura Iwasaki
  • Publication number: 20210202013
    Abstract: Apparatus having a string of series-connected memory cells comprising a plurality of principal memory cells and a plurality of dummy memory cells might have a controller configured to cause the apparatus to apply a first programming pulse to a particular dummy memory cell of the plurality of dummy memory cells sufficient to increase a threshold voltage of the particular dummy memory cell to a voltage level sufficient to cause the particular dummy memory cell to remain deactivated during a read operation on the string of series-connected memory cells, and to concurrently apply a second programming pulse to each principal memory cell of the plurality of principal memory cell sufficient to increase threshold voltages of at least a portion of the plurality of principal memory cells.
    Type: Application
    Filed: June 8, 2020
    Publication date: July 1, 2021
    Applicant: MICRON TECHNOLOGY, INC.
    Inventors: Zhengyi Zhang, Dan Xu, Tomoko Ogura Iwasaki
  • Publication number: 20210199703
    Abstract: Apparatus having an array of memory cells and a controller for access of the array of memory cells, wherein the controller is configured to cause the apparatus to determine capacitance and/or resistance values of an access line in response to applying a reference current to the access line, wherein the access line is connected to control gates of memory cells of the array of memory cells.
    Type: Application
    Filed: May 19, 2020
    Publication date: July 1, 2021
    Applicant: MICRON TECHNOLOGY, INC.
    Inventors: Dan Xu, Jun Xu, Erwin E. Yu
  • Patent number: 11000837
    Abstract: A catalyst for preparing chlorine gas by hydrogen chloride oxidation, comprising the following components calculated according to mass content based on the total weight of the catalyst: 0.5-20 wt % copper; 2-10 wt % manganese; 0.05-2 wt % boron; 0.01-3 wt % chromium; 0.1-10 wt % rare earth metal; 0.1-10 wt % potassium; and 3-15 wt % titanium; also comprising 0.02-1.1 wt % phosphorus; and 0.03-1.9 wt % iron; the carrier content is 55-90 wt %. In the case of a fluidized bed reactor, the present catalyst can achieve a one-way hydrogen chloride conversion rate of 80-85%. Almost all of the 0-1000 mg/kg of chlorinated benzene contained in hydrogen chloride gas can be converted into CO2 and H2O without generating polychlorinated benzene.
    Type: Grant
    Filed: August 5, 2016
    Date of Patent: May 11, 2021
    Inventors: Hongke Zhang, Bo Zhou, Zhangwei Zai, Dan Xu, Yu Yao, Yanlong Xu, Dongke Zhao, Jingjing Yang, Jiansheng Ding, Weiqi Hua
  • Publication number: 20210121373
    Abstract: This present invention provides dissolvable solid articles comprising multiple layers of flexible, dissolvable, porous sheets, in which a coating composition is present on at least one internal surface of at least one sheet in said solid articles. The present invention also provides a process for making such solid articles.
    Type: Application
    Filed: October 19, 2020
    Publication date: April 29, 2021
    Inventors: Hongsing TAN, Carl David MAC NAMARA, Min JIANG, Zhaoqi FAN, Robert Wayne GLENN, JR., Dan XU, Zeying HUANG
  • Patent number: 10960091
    Abstract: The invention provides a UV illumination device for sterilizing and disinfecting a desired item or area. The device is having a built-in camera and UV light source in order to disinfect and sterilize the desired item or area. The device automatically detects the human presence and the acts as a normal household light and can be fit inside the conventional light bulb or tube light holder. Further, the device uses an artificial intelligence module, object detection module, machine learning module, localization module, and a plurality of sensors to easily detect the application area and act according to parameters of a particular item. Furthermore, the device can be manually controlled by using a remote device which is having a display where the user can select, identify, prioritize the items and can adjust the time and intensity of the light projection based upon his/her own intellect.
    Type: Grant
    Filed: October 2, 2018
    Date of Patent: March 30, 2021
    Assignee: FUTUREMEDIX, LLC
    Inventors: Alain Dijkstra, Jonathan James Knight, Jooeun Kim, Yong Zhang, Dan Xu
  • Publication number: 20200364518
    Abstract: The present application relates to an object prediction method and apparatus, an electronic device, and a storage medium. The method is applied to a neural network and includes: performing feature extraction processing on a to-be-predicted object to obtain feature information of the to-be-predicted object; determining multiple intermediate prediction results for the to-be-predicted object according to the feature information; performing fusion processing on the multiple intermediate prediction results to obtain fusion information; and determining multiple target prediction results for the to-be-predicted object according to the fusion information.
    Type: Application
    Filed: August 5, 2020
    Publication date: November 19, 2020
    Inventors: Dan XU, Wanli OUYANG, Xiaogang WANG, Sebe NICU