Abstract: Medication delivery system including a container, reservoir, or chamber for medium or fluid, and a mechanism or driving components configurable outside of medium or fluid chamber for advancing a plunger to dispense medium or fluid. The system can include syringe-style drug container, reservoir, or chamber, containing medium or fluid dispensable by advancing plunger disposed inside the container, where the container includes a sliceable portion and where a cutter or slicer is configurable on plunger holder or pusher behind plunger such that cutter cuts through sliceable portion of container as plunger is advanced dispensing medium out of container. The present disclosure is further directed to a patch pump comprising the system as described above. The present disclosure is further directed to a medicament delivery device comprising the system as described above.