Patents by Inventor Dana Jo Orten

Dana Jo Orten has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for inhibiting transcription of the cyclic AMP responsive element binding protein and the activating transcription factor 1
    Patent number: 5844096
    Abstract: The present invention relates to members of the cyclic AMP responsive element binding protein/activating transcription factor 1 (CREB/ATF1) family of transcription factors. An embodiment of this invention constitutes an inhibitory agent (e.g., an antibody, small molecule or polypeptide) which binds to a fragment, spanning from about position 167 to about 181 of the amino acid sequence of the ATF1 protein bound to the target gene, with sufficient binding affinity to cause disassociation of ATF1 from the DNA of the target gene and/or prevent ATF1 from binding thereto through a currently unknown mechanism. As a result, transcription is prevented or, at least, inhibited, resulting in events of consequence to a virus or cell.
    Type: Grant
    Filed: December 20, 1996
    Date of Patent: December 1, 1998
    Assignee: Board of Regents of The University of Nebraska
    Inventors: Steven H. Hinrichs, Dana Jo Orten
  • Methods for inhibiting transcription of the cyclic AMP responsive element binding protein and the activating transcription factor 1
    Patent number: 5641486
    Abstract: The present invention relates to members of the cyclic AMP responsive element binding protein/activating transcription factor 1 (CREB/ATF1) family of transcription factors. An embodiment of this invention constitutes an inhibitory agent (e.g., an antibody, small molecule or polypeptide) which binds to a fragment, spanning from about position 167 to about 181 of the amino acid sequence of the ATF1 protein bound to the target gene, with sufficient binding affinity to cause disassociation of ATF1 from the DNA of the target gene and/or prevent ATF1 from binding thereto through a currently unknown mechanism. As a result, transcription is prevented or, at least, inhibited, resulting in events of consequence to a virus or cell.
    Type: Grant
    Filed: March 18, 1994
    Date of Patent: June 24, 1997
    Assignee: Board of Regents of the University of Nebraska
    Inventors: Steven H. Hinrichs, Dana Jo Orten