Patents by Inventor Dana L. Siegel

Dana L. Siegel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL INHIBITORS OF RHO KINASE
    Publication number: 20090318485
    Abstract: The present invention relates to compounds and methods which may be useful as inhibitors of Rho kinase for the treatment or prevention of disease.
    Type: Application
    Filed: July 20, 2007
    Publication date: December 24, 2009
    Applicant: KALYPSYS, INC.
    Inventors: Allen J. Borchardt, Elisabeth M.M. Gardiner, Stewart A. Noble, Dana L. Siegel
  • HETEROCYCLIC MODULATORS OF TGR5
    Publication number: 20090105124
    Abstract: Disclosed herein are new heterocyclic compounds and compositions and their application as pharmaceuticals for the treatment of disease. Methods of modulation of TGR5 activity in a human or animal subject are also provided for the treatment diseases mediated by TGR5.
    Type: Application
    Filed: August 18, 2008
    Publication date: April 23, 2009
    Applicant: Kalypsys, Inc.
    Inventors: Nicholas D. Smith, Joseph E. Payne, Timothy Z. Hoffman, Celine Bonnefous, Anothony B. Pinkerton, Dana L. Siegel
  • HETEROCYCLIC MODULATORS OF TGR5 FOR TREATMENT OF DISEASE
    Publication number: 20090054304
    Abstract: The present invention relates to compounds useful as modulators of TGR5 and methods for the treatment or prevention of metabolic, cardiovascular, and inflammatory diseases.
    Type: Application
    Filed: August 8, 2008
    Publication date: February 26, 2009
    Applicant: KALYPSYS, INC.
    Inventors: Mark R. Herbert, Anthony B. Pinkerton, Dana L. Siegel
  • QUINAZOLINONE MODULATORS OF TGR5
    Publication number: 20090035306
    Abstract: The present invention relates to quinazolinone compounds useful as modulators of TGR5 and methods for the treatment or prevention of metabolic, cardiovascular, and inflammatory diseases.
    Type: Application
    Filed: November 20, 2007
    Publication date: February 5, 2009
    Applicant: KALYPSYS, INC.
    Inventors: Anthony B. Pinkerton, Ayman Kabakibi, Timothy Z. Hoffman, Dana L. Siegel, Stewart A. Noble