Patents by Inventor Dana L. Smith

Dana L. Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for identifying disruptors of biological pathways using genetic selection
    Patent number: 6365347
    Abstract: Macromolecule libraries constructed by transforming host cells with a collection of recombinant vectors that encode chimeras comprised of a carrier protein and a random peptide sequence are generated. The chimera is expressed intracellularly so that peptide inhibitors of biological pathways are identified through genetic selection. Peptides having a wide variety of uses such as therapeutic of diagnostic reagents, may thus be identified without any prior information on the structure of the desired target for the chimera.
    Type: Grant
    Filed: April 10, 1998
    Date of Patent: April 2, 2002
    Assignee: The Regents of the University of California
    Inventors: Andrew W. Murray, Dana L. Smith, Peter K. Sorger, Thea C. Norman