Abstract: The disclosure relates generally to methods of treating allergies in subjects, methods of monitoring treatment of allergies in subjects, methods of diagnosing allergies in subjects, methods for determining whether subjects are candidates for allergy treatments, methods and kits for detecting allergies or allergens, methods for identifying cross-reactive allergens, antibodies that bind allergenic proteins and methods of identifying the same, and multiple allergen compositions and methods of preparing the same.

Abstract: Methods of making mixed allergen drug products are provided, wherein the mixed allergen drug products are of known potency and identity and substantially free of replication viable organisms.