Abstract: Devices and methods for providing real-time feedback of conversational attributes are provided. An audio signal comprising speech is received. The audio signal is divided into a plurality of sequential windows. A plurality of features is extracted from each sequential window of the audio signal. Each plurality of features is sequentially provided to a trained classifier and a speech attribute of the corresponding window of the audio signal is received therefrom. After receiving each speech attribute, and based upon that speech attribute and speech attributes of prior windows, a conversational attribute is generated. A user-perceivable output indicative of the conversational attribute is provided.

Abstract: Botulinum toxin may be used to inhibit the cascade of events leading to acne. Results in preliminary studies have been dramatic. Withoout wishing to be bound by this theory, it is believed that botulinum toxin achieves this result through parasympathetic effects, inhibiting sweat gland activity, stimulating keratinocyte locomotion, anti-inflammatory effects, and possibly anti-androgenic effects. Botulinum toxin can play an important role in decreasing and even preventing the formation of acne.