Abstract: A distributed wireless system comprises a controlling node (20) and two or more antenna processing nodes (22) communicatively coupled to the controlling node (20) but spatially separated from each other and from the controlling node (20). A method in the controlling node (20) comprises controlling (1110) a first subset of the antenna processing nodes (22) to transmit synchronization signal blocks, SSBs, having a first SSB identifier, the first subset including one or more of the antenna processing nodes, and controlling (1120) a second subset of the antenna processing nodes (22) to transmit SSBs having a second SSB identifier, the second subset including one or more of the antenna processing nodes (22) and being disjoint with the first subset.

Abstract: A wireless device (10) receives control data provided by a node (100) of the wireless communication network. The control data indicates a set of one or more supported machine-learning models for encoding and decoding of uplink control signaling from the wireless device (10) to the node (100). The wireless device (10) selects one or more of the machine-learning models from the set. Based on at least one of the one or more selected machine-learning models, the wireless device (10) encodes uplink control signaling from the wireless device (10) to the node (100).

Abstract: In an example embodiment, a system comprises a chain of serially coupled nodes, including a central processing node (CPN) and one or more radio communications nodes (RCNs). The CPN couples to a first RCN in the chain via a dielectric waveguide (DWG) link and any further RCNs in the chain are successively connected in serial fashion from the first RCN via further (DWG) links. The CPN generates outbound radio carrier signals that are waveguide-propagated in a downstream direction of the chain, for over-the-air (OTA) by targeted ones of the RCNs, while radio carrier signals received via OTA reception by respective ones of the RCNs are waveguide propagated as inbound radio signals in an upstream direction of the chain, for processing by the CPN. Advantages from he contemplated system include greatly simplified implementation of the RCNs, with lower cost and power consumption. Further, strategic placement of failover CPNs and DWG links provide for continued operation in the face of CPN or DWG link failures.

Abstract: The present application relates to a vector comprising a polynucleotide encoding CYP4V2 and a promoter operably linked to the polynucleotide encoding CYP4V2. The vector described herein has a good expression effect, high expression speed, and more stable expression intensity. The present application also provides cells, pharmaceutical compositions, and kits comprising the vector, and methods for treating, alleviating, and/or preventing a disease or disorder associated with retinal pigment epithelium (RPE) atrophy.

Abstract: The present application relates to the use of CYP4V2 and RdCVF in the manufacture of a medicament for treating, alleviating, and/or preventing a disease or disorder associated with retinal pigment epithelium (RPE) atrophy. The present application also relates to an isolated nucleic acid molecule comprising a polynucleotide encoding CYP4V2 and a polynucleotide encoding RdCVF. The present application also relates to an amino acid sequence encoded by the isolated nucleic acid molecule, a vector comprising the isolated nucleic acid molecule, and a cell comprising the nucleic acid or the vector as well as use thereof in the manufacture of a medicament for treating, alleviating, and/or preventing a disease or disorder associated with retinal pigment epithelium (RPE) atrophy.

Abstract: A vector includes a polynucleotide encoding CYP4V2 and a promoter operably linked to the polynucleotide encoding CYP4V2. The vector has a good expression effect, high expression speed, and more stable expression intensity. Cells, pharmaceutical compositions, and kits can include the vector. Methods for treating, alleviating, and/or preventing a disease or disorder associated with retinal pigment epithelium (RPE) atrophy can include administering the vector to a subject.

Abstract: One or more embodiments herein relate to a method for an uplink transmission timing adjustment in a wireless communication device served by a network node and configured to operate in a coverage enhancement mode. The coverage enhancement mode comprises a repetitive transmission of a first uplink signal during a first repetition period. The method comprises determining a change in a downlink timing (210), determining whether the first repetition period is ongoing (240); and in response to the change in the downlink timing and the first repetition period being ongoing, performing an adjustment of an uplink transmission timing outside the first repetition period (260).

Abstract: The present application relates to a fusion protein and use thereof. The fusion protein comprises RdCVF and a signal peptide, wherein the signal peptide is an amino acid sequence set forth in any one of SEQ ID NOs: 27-31 and 33. The present application also relates to an isolated nucleic acid molecule comprising a) a polynucleotide encoding RdCVF and b) a polynucleotide encoding a signal peptide. The present application also provides a vector, a cell, and a pharmaceutical composition containing the nucleic acid molecule, as well as medical use thereof. The fusion protein and/or isolated nucleic acid molecule described herein can effectively increase the secretion of RdCVF.

Abstract: A distributed wireless system comprises a controlling node (20) and two or more antenna processing nodes (22) communicatively coupled to the controlling node (20) but spatially separated from each other and from the controlling node (20). A method in the controlling node (20) comprises controlling (1110) a first subset of the antenna processing nodes (22) to transmit synchronization signal blocks, SSBs, having a first SSB identifier, the first subset including one or more of the antenna processing nodes, and controlling (1120) a second subset of the antenna processing nodes (22) to transmit SSBs having a second SSB identifier, the second subset including one or more of the antenna processing nodes (22) and being disjoint with the first subset.

Abstract: The present application relates to the use of CYP4V2 and RdCVF in the manufacture of a medicament for treating, alleviating, and/or preventing a disease or disorder associated with retinal pigment epithelium (RPE) atrophy. The present application also relates to an isolated nucleic acid molecule comprising a polynucleotide encoding CYP4V2 and a polynucleotide encoding RdCVF. The present application also relates to an amino acid sequence encoded by the isolated nucleic acid molecule, a vector comprising the isolated nucleic acid molecule, and a cell comprising the nucleic acid or the vector as well as use thereof in the manufacture of a medicament for treating, alleviating, and/or preventing a disease or disorder associated with retinal pigment epithelium (RPE) atrophy.

Abstract: Embodiments disclosed herein relate to a method in a wireless communication device that operates in an enhanced coverage mode, the enhanced coverage mode comprising sequential repetition of messages sent from the wireless communication device to a network node. An example method includes: receiving a Timing Advance Command TAC from the network node; and adapting a time at which the TAC is applied, wherein a time difference between the time at which the TAC is applied and a time at which the TAC is received shall be greater than or equal to a specified time depending on a type of the used Radio Access Technology, such that application of the TAC does not occur during a period after a first subframe of a repeated uplink transmission till the end of the repeated uplink transmission.