Patents by Inventor Danhong Zhu

Danhong Zhu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Therapeutic Supernatant from Cell-Seeded Substrates and Related Methods
    Publication number: 20240049701
    Abstract: Disclosed herein are methods and compositions for the identification of viability enhancing cell features and substrate features as they relate to post-cryopreservation survival of substrate seeded cells. Embodiments of the present invention further involve identification of cell features to manufacture a supernatant that is useful for cell culturing and treatment of various diseases.
    Type: Application
    Filed: October 10, 2023
    Publication date: February 15, 2024
    Applicants: University of Southern California, The Regents of the University of California
    Inventors: Britney O. Pennington, Jeffrey K. Bailey, Mohamed A. Faynus, Cassidy Arnold, Lincoln V. Johnson, Dennis O. Clegg, Mark S. Humayun, David R. Hinton, Danhong Zhu, Debbie Mitra
  • Cryopreservation of cell-seeded substrates and related methods
    Patent number: 11825839
    Abstract: Disclosed herein are methods and compositions for the identification of viability enhancing cell features and substrate features as they relate to post-cryopreservation survival of substrate seeded cells. Embodiments of the present invention further involve identification of cell features to manufacture a supernatant that is useful for cell culturing and treatment of various diseases.
    Type: Grant
    Filed: August 30, 2019
    Date of Patent: November 28, 2023
    Assignees: University of Southern California, The Regents of the University of California
    Inventors: Britney O. Pennington, Jeffrey K. Bailey, Mohamed A. Faynus, Cassidy Arnold, Lincoln V. Johnson, Dennis O. Clegg, Mark S. Humayun, David R. Hinton, Danhong Zhu, Debbie Mitra
  • Method of cryopreservation of stem cell-derived retinal pigment epithelial cells on polymeric substrate
    Patent number: 11533908
    Abstract: Disclosed herein are methods and compositions for the cryopreservation of stem cells, such as stem-cell derived retinal pigment epithelial cells, that have been seeded onto and cultured on a substrate, such as a polymeric substrate. Such cryopreserved stem cells are useful for cell therapies, such as treatment of ocular damage or disease.
    Type: Grant
    Filed: October 21, 2019
    Date of Patent: December 27, 2022
    Assignee: University of Southern California
    Inventors: Danhong Zhu, David R. Hinton, Ashish Ahuja, Mark S. Humayun
  • CRYOPRESERVATION OF CELL-SEEDED SUBSTRATES AND RELATED METHODS
    Publication number: 20200077641
    Abstract: Disclosed herein are methods and compositions for the identification of viability enhancing cell features and substrate features as they relate to post-cryopreservation survival of substrate seeded cells. Embodiments of the present invention further involve identification of cell features to manufacture a supernatant that is useful for cell culturing and treatment of various diseases.
    Type: Application
    Filed: August 30, 2019
    Publication date: March 12, 2020
    Applicants: University of Southern California, The Regents of the University of California
    Inventors: Britney O. Pennington, Jeffrey K. Bailey, Mohamed A. Faynus, Cassidy Arnold, Lincoln V. Johnson, Dennis O. Clegg, Mark S. Humayun, David R. Hinton, Danhong Zhu, Debbie Mitra
  • Method of Cryopreservation of Stem Cell-Derived Retinal Pigment Epithelial Cells on Polymeric Substrate
    Publication number: 20200045957
    Abstract: Disclosed herein are methods and compositions for the cryopreservation of stem cells, such as stem-cell derived retinal pigment epithelial cells, that have been seeded onto and cultured on a substrate, such as a polymeric substrate. Such cryopreserved stem cells are useful for cell therapies, such as treatment of ocular damage or disease.
    Type: Application
    Filed: October 21, 2019
    Publication date: February 13, 2020
    Applicant: University of Southern California
    Inventors: Danhong Zhu, David R. Hinton, Ashish Ahuja, Mark S. Humayun
  • Method of cryopreservation of stem cell-derived retinal pigment epithelial cells on polymeric substrate
    Patent number: 10470457
    Abstract: Disclosed herein are methods and compositions for the cryopreservation of stem cells, such as stem-cell derived retinal pigment epithelial cells, that have been seeded onto and cultured on a substrate, such as a polymeric substrate. Such cryopreserved stem cells are useful for cell therapies, such as treatment of ocular damage or disease.
    Type: Grant
    Filed: January 27, 2017
    Date of Patent: November 12, 2019
    Assignee: University of Southern California
    Inventors: Danhong Zhu, David Hinton, Ashish Ahuja, Mark Humayun
  • METHOD OF CRYOPRESERVATION OF STEM CELL-DERIVED RETINAL PIGMENT EPITHELIAL CELLS ON POLYMERIC SUBSTRATE
    Publication number: 20170196221
    Abstract: Disclosed herein are methods and compositions for the cryopreservation of stem cells, such as stem-cell derived retinal pigment epithelial cells, that have been seeded onto and cultured on a substrate, such as a polymeric substrate. Such cryopreserved stem cells are useful for cell therapies, such as treatment of ocular damage or disease.
    Type: Application
    Filed: January 27, 2017
    Publication date: July 13, 2017
    Inventors: Danhong Zhu, David Hinton, Ashish Ahuja, Mark Humayun
  • METHOD OF CRYOPRESERVATION OF STEM CELL-DERIVED RETINAL PIGMENT EPITHELIAL CELLS ON POLYMERIC SUBSTRATE
    Publication number: 20140045264
    Abstract: Disclosed herein are methods and compositions for the cryopreservation of stem cells, such as stem-cell derived retinal pigment epithelial cells, that have been seeded onto and cultured on a substrate, such as a polymeric substrate. Such cryopreserved stem cells are useful for cell therapies, such as treatment of ocular damage or disease.
    Type: Application
    Filed: April 27, 2012
    Publication date: February 13, 2014
    Applicant: UNIVERSITY OF SOUTHERN CALIFORNIA
    Inventors: Danhong Zhu, David Hinton, Ashish Ahuja, Mark Humayun