Abstract: Methods and systems for managing the distribution of a drug comprising a food allergen are described herein. Exemplary methods allow for the enrollment of distributors, pharmacies, healthcare settings, healthcare providers, and/or patients in a drug distribution management database for the drug, wherein distribution or provision of the drug is contingent on ensuring enrollment of one or more of the entities in the drug distribution management database. Other methods utilizing the drug distribution management database are also described.

Abstract: Described herein are egg white protein formulations, dosage containers containing the egg white protein formulations, methods of making the egg white protein formulations and dosage containers, and methods of controlling the quality of the egg white protein formulations, materials for manufacturing the egg white protein formulation (such as dried egg white protein powder), and the dosage containers. Further described herein are oral immunotherapy methods for treating an egg allergy. The method includes orally administering to the patient doses of a pharmaceutical composition comprising egg white protein according to an oral immunotherapy schedule. Also described herein are methods of adjusting a dosage of the pharmaceutical composition during oral immunotherapy if the patient experiences an adverse event related to the administration of a dose or a concurrent factor associated with increased sensitivity to an allergen that is not related to the administration of the dose.

Abstract: Methods and systems for managing the distribution of a drug comprising a food allergen are described herein. Exemplary methods allow for the enrollment of distributors, pharmacies, healthcare settings, healthcare providers, and/or patients in a drug distribution management database for the drug, wherein distribution or provision of the drug is contingent on ensuring enrollment of one or more of the entities in the drug distribution management database. Other methods utilizing the drug distribution management database are also described.

Abstract: The present disclosure relates to improved oral immunotherapy methods for treating peanut allergy. In certain embodiments, the disclosure provides methods for continuing an oral immunotherapy for the treatment of a peanut allergy after missing a scheduled oral administration of one or more consecutive doses of a pharmaceutical composition comprising peanut protein.

Abstract: The present disclosure relates to improved oral immunotherapy methods for treating peanut allergy. The disclosure provides methods for treating a subject for a peanut allergy by an oral immunotherapy comprising an up-dosing phase and a maintenance phase. In certain embodiments, the methods comprise non-daily administration to the subject of a maintenance phase dose. In certain embodiments, the methods comprise administering a maintenance phase dose for more than 24 weeks. In other embodiments, the disclosure provides methods for reducing the risk of an allergic adverse event in a subject receiving an oral immunotherapy dosage therapy.

Abstract: Methods of treating, preventing or managing hematologic disorders, such as leukemia are disclosed. The methods encompass the administration of SNS-595. Also provided are methods of treatment using this compound with chemotherapy, radiation therapy, hormonal therapy, biological therapy or immunotherapy. In certain embodiments, the method of treatment comprise administering SNS-595 in combination with Ara-C. Pharmaceutical compositions and single unit dosage forms suitable for use in the methods are also disclosed.

Abstract: The present invention relates to SNS-595 and methods of treating cancer using the same.

Abstract: The present invention relates to SNS-595 and methods of treating cancer using the same.

Abstract: The present invention relates to SNS-595 and methods of treating cancer using the same.

Abstract: This invention provides a new method whereby high hazard employers, that is, those employers with a high rate of work-related injuries and illnesses, can be individually identified and ranked based on their work hazardousness within a specified geographical area. The invention involves the processes of creating a firm's average weekly wage, a firm's employment, a firm's frequency of injuries and illnesses, a firm's severity of injuries and illnesses, a firm's resource efficiency factor, a firm's preventable nature factor, and a firm's hazard rating values. The processes result in a ranked listing of the most hazardous employers.