Abstract: A reconfigurable chair includes features that open up new sitting and resting positions for the user. The chair includes rotatable lateral side rests and a tilt adjustable back rest which when reconfigured, provide auxiliary resting platforms to support the body in different sitting and resting positions. The backrest may include a rotatable feature so that the backrest may be moved from an upright position to a flat position adding another level of support. A height adjustment mechanism may adjust the height of the backrest to add to the reconfigurability of the chair. Some embodiments include one or more gas pistons providing user-controlled adjustment of elements into any of an infinite number of user-controlled positions.

Abstract: A reconfigurable chair includes features that open up new sitting and resting positions for the user. The chair includes rotatable lateral side rests and a tilt adjustable back rest which when reconfigured, provide auxiliary resting platforms to support the body in different sitting and resting positions. The backrest may include a rotatable feature so that the backrest may be moved from an upright position to a flat position adding another level of support. A height adjustment mechanism may adjust the height of the backrest to add to the reconfigurability of the chair.

Abstract: Provided are compositions and methods for activating latent Human Immunodeciency Virus (HIV). The compositions and methods may utilize a recombinant peptide that has a DNA-binding zinc finger domain specific to the HIV LTR sequence. The recombinant peptide may also have a transcription factor (e.g. a transcription activator) that is conjuated to the zinc finger domain. Also provided are methods of treating HIV in a subject in need of the treatment. The method may involve activation of latent HIV in cells of the subject and selectively removing such cells from the subject, providing complete and effective treatment of HIV.

Abstract: Disclosed are small molecule inhibitors of SLC15A4, and methods of using them to treat pDC-mediated diseases and conditions.

Abstract: Provided are compositions and methods for activating latent Human Immunodeficiency Virus (HIV). The compositions and methods may utilize a recombinant peptide that has a DNA binding zinc finger domain specific to the HIV long terminal repeat (LTR) sequence. The recombinant peptide may also have a transcription factor (e.g. a transcription activator) that is conjugated to the zinc finger domain. Also provided are methods of treating HIV in a subject in need of the treatment. The method may involve activation of latent HIV in cells of the subject and selectively removing such cells from the subject, providing complete and effective treatment of HIV.

Abstract: A reconfigurable chair includes features that open up new sitting and resting positions for the user. The chair includes rotatable lateral side rests and a tilt adjustable back rest which when reconfigured, provide auxiliary resting platforms to support the body in different sitting and resting positions. The backrest may include a rotatable feature so that the backrest may be moved from an upright position to a flat position adding another level of support. A height adjustment mechanism may adjust the height of the backrest to add to the reconfigurability of the chair.

Abstract: Systems, devices, and methods are described for providing, among other things, a neck and spine strengthening device. The strengthening device includes a spinal resistance assembly configured to apply a resist force or to resist rotation about at least a first axis, and a head affixing assembly configured to secure to a head of a user during use. The strengthening device is instrumented with sensors and an embedded computing system configured to securely exchange exercise performance and configuration data with local client devices, and to monitor and record exercise activity and exercise performance data.

Abstract: Provided are compositions and methods for activating latent Human Immunodeficiency Virus (HIV). The compositions and methods may utilize a recombinant peptide that has a DNA binding zinc finger domain specific to the HIV long terminal repeat (LTR) sequence. The recombinant peptide may also have a transcription factor (e.g. a transcription activator) that is conjugated to the zinc finger domain. Also provided are methods of treating HIV in a subject in need of the treatment. The method may involve activation of latent HIV in cells of the subject and selectively removing such cells from the subject, providing complete and effective treatment of HIV.

Abstract: Systems, devices, and methods are described for providing, among other things, a neck and spine strengthening device. In an embodiment, the neck strengthening device includes a spinal resistance assembly including at least one resistance component configured to apply a resist force or to resist rotation about a first axis. In an embodiment, the spinal resistance assembly permits lateral neck rotation of a user about the first axis while substantially limiting flexional and extensional movement. In an embodiment, the neck strengthening device includes a device securing assembly configured to physically anchor the device to an anchoring structure. In an embodiment, the neck strengthening device includes a head affixing assembly configured to secure to a head of a user during use.

Abstract: Systems, methods, and mediums storing programs for trading financial assets. The method can include receiving a first order specifying a first quantity of financial assets to be traded according to a volume-weighted average price for a trading session and executing the first order during the trading session through algorithmic or traditional trading of the first quantity of financial assets on an exchange. The method can also include creating a second order specifying the first quantity of financial assets to be traded according to a volume-weighted average price measured from a moment of cross to an end of the trading session and exposing the second order to a non-exchange crossing pool concurrently with the execution of the first order. The crossing pool can include multiple orders. The method can include continuously determining whether any of the plurality of orders in the crossing pool can be crossed with the second order.

Abstract: There is provided a portable riser having an operator actuated lifting assist assembly operatively coupled to a riser deck. In one aspect, there is a first pivot mechanism coupled to a first support leg and adapted to initiate upward movement of the portable riser from a collapsed position when a downward force is applied to the first support leg, and a second pivot mechanism coupled to a second support leg and adapted to continue the upward movement. The lifting assist assembly provides a lifting force that continues upward movement to an upright position where the portable riser in locked. There is included a riser unlocking means for unlocking the lifting assist assembly. The portable riser remains in the upright position until the riser unlocking means is operated and a collapsing force is applied to the portable riser sufficient to overcome the lifting force and enable collapsed of the portable riser.

Abstract: There is provided a portable riser having an operator actuated lifting assist assembly operatively coupled to a riser deck. In one aspect, there is a first pivot mechanism coupled to a first support leg and adapted to initiate upward movement of the portable riser from a collapsed position when a downward force is applied to the first support leg, and a second pivot mechanism coupled to a second support leg and adapted to continue the upward movement. The lifting assist assembly provides a lifting force that continues upward movement to an upright position where the portable riser in locked. There is included a riser unlocking means for unlocking the lifting assist assembly. The portable riser remains in the upright position until the riser unlocking means is operated and a collapsing force is applied to the portable riser sufficient to overcome the lifting force and enable collapsed of the portable riser.

Abstract: There is provided a portable riser having an operator actuated lifting assist assembly operatively coupled to a riser deck. In one aspect, there is a first pivot mechanism coupled to a first support leg and adapted to initiate upward movement of the portable riser from a collapsed position when a downward force is applied to the first support leg, and a second pivot mechanism coupled to a second support leg and adapted to continue the upward movement. The lifting assist assembly provides a lifting force that continues upward movement to an upright position where the portable riser in locked. There is included a riser unlocking means for unlocking the lifting assist assembly. The portable riser remains in the upright position until the riser unlocking means is operated and a collapsing force is applied to the portable riser sufficient to overcome the lifting force and enable collapsed of the portable riser.

Abstract: There is provided an apparatus for a folding table assembly comprising a lifting assist center torsion bar assembly, a lift off caster assembly and a stability locking mechanism. A folding table assembly with a lifting assist mechanism provides a lifting assist force during a portion of the folding process of a foldable table from an unfolded use position to a folded storage position. A lift off caster assembly maintains an unfolded table assembly in a stationary position and prevents the unfolded table from wandering or deviating from its original location on the floor. There is also provided a stability locking mechanism that can set the folding table in a folded and stable semi-closed position.

Abstract: There is provided an apparatus for a folding table assembly comprising a lifting assist center torsion bar assembly, a lift off caster assembly and a stability locking mechanism. A folding table assembly with a lifting assist mechanism provides a lifting assist force during a portion of the folding process of a foldable table from an unfolded use position to a folded storage position. A lift off caster assembly maintains an unfolded table assembly in a stationary position and prevents the unfolded table from wandering or deviating from its original location on the floor. There is also provided a stability locking mechanism that can set the folding table in a folded and stable semi-closed position.

Abstract: A hydraulic shear for bar stock including a die housing constructed so that the forces produced by the shearing operation are absorbed by interlocking joints. The structure assures that there are no welded or bolted joints in the die housing in a position to receive the stresses resulting from the shearing operation. The shear comprises a three bolster arrangement wherein a hydraulic cylinder is positioned between a first end bolster and a center bolster and fitted into recesses provided in such bolsters. The die housing is positioned between the center bolster and the other end bolster and similarly fitted into recesses provided in those bolsters. Top and bottom plates are recessed and interfitted over the die retainer end plates to provide an interlocking construction eliminating the need for bolts and welds in the die housing. Such arrangement not only provides a strong stable unit, but also allows efficient access to the dies, such as for die changes.