Abstract: This invention relates to methods of screening for anti-PACAP antibodies, or anti-PACAP receptor antibodies, and antigen binding fragments thereof, for potential use in treating or preventing PACAP-associated photophobia or light aversion, and therapeutic compositions containing and methods of using anti-PACAP antibodies, or anti-PACAP receptor antibodies, and antigen binding fragments thereof.

Abstract: Disclosed is a new location threat monitoring solution that leverages deep learning (DL) to process data from data sources on the Internet, including social media and the dark web. Data containing textual information relating to a brand is fed to a DL model having a DL neural network trained to recognize or infer whether a piece of natural language input data from a data source references an address or location of interest to the brand, regardless of whether the piece of natural language input data actually contains the address or location. A DL module can determine, based on an outcome from the neural network, whether the data is to be classified for potential location threats. If so, the data is provided to location threat classifiers for identifying a location threat with respect to the address or location referenced in the data from the data source.

Abstract: Embodiments of the present disclosure generally relate to a multilayer stack used as a mask in extreme ultraviolet (EUV) lithography and methods for forming a multilayer stack. In one embodiment, the method includes forming a carbon layer over a film stack, forming a metal rich oxide layer on the carbon layer by a physical vapor deposition (PVD) process, forming a metal oxide photoresist layer on the metal rich oxide layer, and patterning the metal oxide photoresist layer. The metal oxide photoresist layer is different from the metal rich oxide layer and is formed by a process different from the PVD process. The metal rich oxide layer formed by the PVD process improves adhesion of the metal oxide photoresist layer and increases the secondary electrons during EUV lithography, which leads to decreased EUV dose energies.

Abstract: A transfer time, at which control of automatically inserting advertisements into a broadcast is to be passed from a first advertisement management system to a second advertisement management system, is scheduled to occur within a spot break. During a first portion of the spot break controlled by the first advertisement management system, a determination is made that playout of a final advertisement scheduled for broadcast during the first portion of the spot break cannot be completed prior to the transfer time. A run-last-spot parameter indicating whether the first advertisement management system is permitted to pass control of automatically inserting advertisements into the broadcast prior to the transfer time is obtained. Control of automatically inserting advertisements into the broadcast is conditionally passed from the first advertisement management system to the second advertisement management system based on the run-last-spot parameter.

Abstract: Disclosed herein are embodiments of a wound treatment apparatus with electronic components integrated within a wound dressing. In some embodiments, a wound dressing apparatus can comprise a wound contact layer, an absorbent layer over the wound contact layer, the absorbent layer comprising one or more apertures, a cover layer configured to cover and form a seal over the wound contact layer and the absorbent layer, and an electronics assembly comprising a negative pressure source. A portion of the cover layer overlying the one or more apertures in the absorbent layer can be configured to be compressed within the aperture in the absorbent layer when negative pressure is applied to the wound dressing apparatus. The compressed cover layer can indicate a level of negative pressure below the cover layer. In some embodiments, the wound dressing apparatus can comprise an indicator material layer and a cover layer configured to cover and form a seal over the wound contact layer and the indicator material layer.

Abstract: An intermediate data set can be generated based on an image of a set of objects, where each of the set of objects includes a plastic. A predicted chemometric property can be generated by inputting the intermediate data set to a machine-learning model. The chemometric property can be of a physical output pyrolysis oil produced by performing a pyrolysis processing of the set of objects using a pyrolysis reactor. A result associated with the set of objects can be generated, where the result is based on or includes the predicted chemometric property.

Abstract: A memory is disclosed. The memory may include a first data structure. The first data structure may include a first field to store a first data relating to a command. The memory may also include a second data structure. The second data structure may include a second field to store a second data relating to the command. A first queue stored in the memory may include the first data structure. A second queue stored in the memory may include the second data structure.

Abstract: A system for heating a lens of an optical device may include a mounting surface configured to be mounted on the lens with the mounting surface facing the lens, and a heating element that, with the mounting surface mounted on the lens, is proximate the lens such that heat generated by the heating element prevents dew formation on the lens.

Abstract: A memory is disclosed. The memory may include a first data structure and a second data structure. The first data structure may include a first field to store a first data relating to a command, and a related command field, the related command field to store a value. The second data structure may include a second field to store a second data relating to the command. A queue stored in the memory, may include the first data structure. A storage device may be configured to identify the first data structure and the second data structure (405, 705) as related based at least in part on the value.

Abstract: A memory is disclosed. The memory may include a first data structure. The first data structure may include a field, which may store a first pointer to a second data structure. The second data structure may include a second pointer to a data relating to a command and a third pointer to a user data. The memory may also include a queue that may include the first data structure.

Abstract: A message addressed to a user is received. A first model is applied to the message to produce a first output indicative of whether the message is representative of a non-malicious message. The first model is trained using past messages that have been verified as non-malicious messages. It is determined, based on the first output, that the message is potentially a malicious message. Responsive to determining that the message is potentially a malicious email based on the first output, apply a second model to the message to produce a second output indicative of whether the message is representative of a given type of attack. The second model is one of a plurality of models. At least one model included in the plurality of models is associated with characterizing a goal of the malicious message. An action is performed with respect to the message based on the second output.

Abstract: Disclosed in some examples are methods, systems, and machine readable mediums which provide for customized alerts for a user. Alerts may be described by a set of alert parameters. Alert parameters include the type of alerts, the frequency of alerts, and the content of the alerts. While the alert parameters may initially be set based upon the users explicitly entered preferences, the system may monitor one or more indicators to dynamically adjust one or more of the alert parameters. As the indicators allow the automated portfolio management system to respond to the needs of a user, these alerts may increase the personalization of automated portfolio management systems.

Abstract: A magnetically attachable window screen for attachment to a window frame. The window screen includes a plurality of screen frame members. Each frame member includes a first end and a second end wherein the first and second ends are operable to receive a flange member. The window screen also includes a screen corner key with a central magnetic member and two orthogonally opposed flanges extending outwardly in a single plane from the central magnetic member. The flange members of the screen corner key are inserted into the first and second ends of orthogonally opposed adjacent screen frame members to form a fully assembled screen frame. The window screen also includes a plurality of corner key mates inserted into each corner of the screen channel of the window frame. The central magnetic member of the inserted corner key is operable for magnetic attraction to respective corner key mates.

Abstract: The present disclosure provides methods of treating or preventing fatty liver disease and/or lowering cholesterol and LDL cholesterol levels in a subject. The present disclosure further provides methods of lowering expression of Pleckstrin and Sec7 Domain Containing 3 (PSD3) in a subject.

Abstract: A flow regulation system for regulating a flow of a fluid from a fluid reservoir is disclosed having a fluid reservoir container, an effluent conduit adapted to discharge fluid from the fluid reservoir container, and a fluid turbine disposed in the effluent conduit. A generator is operatively connected to the fluid turbine for converting mechanical energy of the fluid turbine to electrical energy, and a power conditioning module is energized by the generator to alter voltage and current characteristics of electricity generated by the generator. A load manager is provided to monitor operational characteristic of the flow regulation systems.

Abstract: Novel compounds, compositions, and methods of using and preparing the same, which may be useful for treating alpha-1 antitrypsin deficiency (AATD).

Abstract: Provided is a method for managing a data migration operation, including creating, by a storage device, a read submission queue entry indicating a location of data at a source storage of the storage device to be copied from the source storage to a target storage, the read submission queue entry including a field including metadata including information for reading the data from the source storage.

Abstract: Single filter and multi-filter endolumenal methods and systems for filtering fluids within the body. In some embodiments a blood filtering system captures and removes particulates dislodged or generated during a surgical procedure and circulating in a patient's vasculature. In some embodiments a filter system protects the cerebral vasculature during a cardiac valve repair or replacement procedure.