Abstract: Novel selective estrogen receptor degraders (SERDs) according to the formula: pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, wherein either R1 or R2 is independently selected from Cl, F, —CF3, or —CH3, and the other is hydrogen, and methods for their use are provided.

Abstract: An ink blend consisting of a polymer, a weakly cross-linking agent and a nanomaterial deposited to form a thin polymer-nanomaterial composite film with unique mechanical and electrical properties suitable for high performance strain sensing applications.

Abstract: A retractable bicycle fender has a bistable Spring strip with an elastomeric grommet at the end. A hole goes through the grommet and the Spring strip to allow mounting on a bicycle seat post. Plastic wings coat the edges of the Spring strip to increase the width of the fender and reduce the noise and rate of recoil. The bicycle fender can be manually extended in wet weather and recoiled in dry weather.

Abstract: An internet video chat capable television with personal computer hardware has a digital screen, a tuner, a camera, a microphone, and a plurality of wireless communication devices and wireless or wired communication ports for connecting to the internet or another digital network and accessories such as a remote, keyboard or a headset. A motherboard, central processing unit, solid state hard drive and associated chipset and other electronic components on par with a personal computer enable installation of a full operating system capable of supporting web applications such as Voice over Internet Protocol and video communications as well as home security, home automation and child minding applications, among many others, without the need for a separate computer. The camera has an infrared option for video monitoring in low light conditions.