Patents by Inventor Daniel Aeschlimann

Daniel Aeschlimann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TRANSGLUTAMINASE 6 AS A DIAGNOSTIC INDICATOR OF AUTOIMMUNE DISEASES
    Publication number: 20130196336
    Abstract: The embodiments relate to the diagnosis of disorders or dysfunctions characterised by autoimmune responses to a novel antigen, transglutaminase 6, by the detection of autoantibodies to the novel antigen.
    Type: Application
    Filed: April 7, 2008
    Publication date: August 1, 2013
    Inventors: Marios Hadjivassilliou, Daniel Aeschlimann
  • Diagnosis of gluten sensitive enteropathy and other autoimmunopathies
    Patent number: 7781169
    Abstract: Method for diagnosis of autoimmune diseases of the GSE-type or associated with gluten sensitive enteropathy comprising taking a sample and testing the sample for antibodies against human tissue transglutaminase, tissue-specific transglutaminases, or other transglutaminases.
    Type: Grant
    Filed: June 28, 2000
    Date of Patent: August 24, 2010
    Inventors: Mats Paulsson, Uwe Odenthal, Neil Smyth, Daniel Aeschlimann, Sarolta Karpati, Miklos Sardy
  • Functionalized derivatives of hyaluronic acid, formation of hydrogels in situ using same, and methods for making and using same
    Publication number: 20070149441
    Abstract: Methods for chemical modification of hyaluronic acid, formation of amine or aldehyde functionalized hyaluronic acid, and the cross-linking thereof to form hydrogels are provided. Functionalized hyaluronic acid hydrogels of this invention can be polymerized in situ, are biodegradable, and can serve as a tissue adhesive, a tissue separator, a drug delivery system, a matrix for cell cultures, and a temporary scaffold for tissue regeneration.
    Type: Application
    Filed: February 13, 2007
    Publication date: June 28, 2007
    Applicant: Orthogene LLC
    Inventors: Daniel Aeschlimann, Paul Bulpitt
  • Functionalized derivatives of hyaluronic acid, formation of hydrogels in situ using same, and methods for making and using same
    Patent number: 7196180
    Abstract: Methods for chemical modification of hyaluronic acid, formation of amine or aldehyde functionalized hyaluronic acid, and the cross-linking thereof to form hydrogels are provided. Functionalized hyaluronic acid hydrogels of this invention can be polymerized in situ, are biodegradable, and can serve as a tissue adhesive, a tissue separator, a drug delivery system, a matrix for cell cultures, and a temporary scaffold for tissue regeneration.
    Type: Grant
    Filed: October 6, 2003
    Date of Patent: March 27, 2007
    Assignee: Orthogene LLC
    Inventors: Daniel Aeschlimann, Paul Bulpitt
  • Functionalized derivatives of hyaluronic acid, formation of hydrogels in situ using same, and methods for making and using same
    Publication number: 20040072793
    Abstract: Methods for chemical modification of hyaluronic acid, formation of amine or aldehyde functionalized hyaluronic acid, and the cross-linking thereof to form hydrogels are provided. Functionalized hyaluronic acid hydrogels of this invention can be polymerized in situ, are biodegradable, and can serve as a tissue adhesive, a tissue separator, a drug delivery system, a matrix for cell cultures, and a temporary scaffold for tissue regeneration.
    Type: Application
    Filed: October 6, 2003
    Publication date: April 15, 2004
    Applicant: ORTHOGENE, L L C.
    Inventors: Daniel Aeschlimann, Paul Bulpitt
  • Functionalized derivatives of hyaluronic acid, formation of hydrogels in situ using same, and methods for making and using same
    Patent number: 6630457
    Abstract: Methods for chemical modification of hyaluronic acid, formation of amine or aldehyde functionalized hyaluronic acid, and the cross-linking thereof to form hydrogels are provided. Functionalized hyaluronic acid hydrogels of this invention can be polymerized in situ, are biodegradable, and can serve as a tissue adhesive, a tissue separator, a drug delivery system, a matrix for cell cultures, and a temporary scaffold for tissue regeneration.
    Type: Grant
    Filed: September 18, 1998
    Date of Patent: October 7, 2003
    Assignee: Orthogene LLC
    Inventors: Daniel Aeschlimann, Paul Bulpitt
  • Method of promoting adhesion between tissue surfaces
    Patent number: 5736132
    Abstract: A formulated biological adhesive composition utilizes tissue transglutaminase in a pharmaceutically acceptable aqueous carrier. The tissue transglutaminase is used in an effective catalytic amount to promote adhesion between tissue surfaces upon treatment thereof by catalyzing the reaction between glutaminyl residues and amine donors of the tissue and/or the enzyme. The carrier contains a divalent metal ion such as calcium to promote said reaction.
    Type: Grant
    Filed: January 29, 1996
    Date of Patent: April 7, 1998
    Assignee: Orthogene, Inc.
    Inventors: Kay Juergensen, Daniel Aeschlimann, Ernst B. Hunziker
  • Biological adhesive composition and method of promoting adhesion between tissue surfaces
    Patent number: 5549904
    Abstract: A formulated biological adhesive composition utilizes tissue transglutaminase in a pharmaceutically acceptable aqueous carrier. The tissue transglutaminase is used in an effective catalytic amount to promote adhesion between tissue surfaces upon treatment thereof by catalyzing the reaction between glutaminyl residues and amine donors of the tissue and/or the enzyme. The carrier contains a divalent metal ion such as calcium to promote said reaction.
    Type: Grant
    Filed: June 3, 1993
    Date of Patent: August 27, 1996
    Assignee: Orthogene, Inc.
    Inventors: Kay Juergensen, Daniel Aeschlimann, Ernst B. Hunziker