Patents by Inventor Daniel Aigner

Daniel Aigner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 7?-hydroxysteroid dehydrogenase mutants and process for the preparation of ursodeoxycholic acid
    Patent number: 11981935
    Abstract: In various aspects and embodiments, the invention provides a nucleic acid molecule comprising a nucleotide sequence encoding a 7?-hydroxysteroid dehydrogenase (7?-HSDH) mutant that catalyzes at least the stereospecific enzymatic reduction of a 7-ketosteroid to the corresponding 7-hydroxysteroid, wherein the mutant has, compared to the wildtype 7?-HSDH of SEQ ID NO:2, a decreased substrate inhibition and/or an altered cofactor usage, and the mutant has, in comparison with the wildtype 7?-HSDH of SEQ ID NO:2, 1 to 15 amino acid additions, substitutions, deletions and/or inversions in the sequence motif VMVGRRE corresponding to positions 36 to 42 of SEQ ID NO:2.
    Type: Grant
    Filed: January 15, 2021
    Date of Patent: May 14, 2024
    Assignee: Pharmazell GmbH
    Inventors: Dirk Weuster-Botz, Michael Braun, Arno Aigner, Boqiao Sun, Christina Kantzow, Sven Bresch, Daniel Bakonyi, Werner Hummel
  • Optochemical sensor
    Patent number: 10876968
    Abstract: An sensor (2) based on an optical-sensing technique measures gaseous or dissolved analytes in a measurement medium (4). The sensor has a sensor housing (6) and an optochemical sensor element (20, 220) arranged within the sensor housing. The optochemical sensor element (220) has a substrate (222), a sensing layer (224) and a barrier layer (230). The barrier layer is arranged to protect the optochemical sensor element from interfering substances (234) present in the measurement medium.
    Type: Grant
    Filed: May 8, 2018
    Date of Patent: December 29, 2020
    Assignee: Mettler-Toledo GmbH
    Inventors: Daniel Aigner, Robert Lettow, Toni Schneider, Martin Winkler, Stefanie Zuber
  • OPTOCHEMICAL SENSOR
    Publication number: 20180328847
    Abstract: An sensor (2) based on an optical-sensing technique measures gaseous or dissolved analytes in a measurement medium (4). The sensor has a sensor housing (6) and an optochemical sensor element (20, 220) arranged within the sensor housing. The optochemical sensor element (220) has a substrate (222), a sensing layer (224) and a barrier layer (230). The barrier layer is arranged to protect the optochemical sensor element from interfering substances (234) present in the measurement medium.
    Type: Application
    Filed: May 8, 2018
    Publication date: November 15, 2018
    Inventors: Daniel Aigner, Robert Lettow, Toni Schneider, Martin Winkler, Stefanie Zuber