Abstract: The system and method provide ways to achieve vascular access, e.g., for chronic hemodialysis. The system includes a port which may be bonded to a vascular graft which is installed between an artery and vein. A movable seal occludes a lumen of the port which when deployed allows access to the blood flow, allowing hemodialysis. A stent may be employed with an extension that is part of the graft. A connector may lock on to the port to deploy the seal to make a connection between the patient and a dialyzer. A cap may cover the port and seal for sterility. Methods of using the system are also disclosed.

Abstract: Systems and methods are provided that reduce or prevent the occurrence of NIH, VR and the resulting VS in the VOT of a GAVF. The system may protect the venous outflow tract of a GAVF from the deleterious physical and biological factors that induce: pathological cellular and biochemical responses which cause neointimal hyperplasia, venous remodeling, thrombosis, venous stenosis, and GAVF-vein anastomotic stenosis, including: a fenestrated expandable stent; and a tubular extension extending from the fenestration. The method protects the venous outflow tract of a GAVF from the deleterious physical and biological factors that induce: pathological cellular and biochemical responses which cause neointimal hyperplasia, venous remodeling, thrombosis, venous stenosis, and GAVF-vein anastomotic stenosis, and include steps of inserting the device into a vein to be used as a VOT; expanding the device; and joining the tubular extension of the device to a GAVF.