Abstract: Described are antihypertensive agents selected from the class consisting of 2[4(tetrahydro-2-furoyl)-piperazino]-4-amino-6,7-dimethoxyquinazoline and 2-[4(tetrahydropyran-2-carbonyl)-piperazinyl]-4-amino-6,7-dimethoxyquinazo line, and pharmaceutically acceptable acid addition salts thereof. The compounds are highly water soluble and can be administered in time release form as well as parenterally, including intravenously.

Abstract: Covers a compound selected from the group consisting of a member of the formula: ##STR1## wherein R.sub.1 is a radial selected from the group consisting of higher branched or straight chain alkyl and cycloalkyl radicals wherein said R.sub.1 radical contains at least six carbon atoms, R.sub.2 is a radical selected from the group consisting of hydrogen, loweralkyl and loweralkanol radicals, wherein said R.sub.2 radical contains 1 - 3 carbon atoms, and R.sub.3 is methoxy; and nontoxic pharmaceutically acceptable acid addition salts thereof. Also covers the use of said compound as a local anesthetic and pharmaceutical compositions comprising said above compounds as the active ingredient.

Abstract: Covers a compound selected from the group consisting of a member of the formula: ##STR1## where R.sub.1 is a radical selected from the group consisting of higher branched or straight chain alkyl and cycloalkyl radicals wherein said R.sub.1 radical contains at least six carbon atoms, R.sub.2 is a radical selected from the group consisting of hydrogen, loweralkyl and loweralkanol radicals, wherein said R.sub.2 radical contains 1-3 carbon atoms, and R.sub.3 is methoxy; and nontoxic pharmaceutically acceptable acid addition salts thereof. Also covers the use of said compound as a local anesthetic and pharmaceutical compositions comprising said above compounds as the active ingredient.

Abstract: A two-step preparation of 3-arylpropyl chloride from the corresponding 2-chloropropiophenone by hydrogenation using two specific catalysts in series.

Abstract: Described are the compounds 2[4(tetrahydro-2-furoyl)-hexahydro-1,4-diazepinyl-1]-4-amino-6,7-dimethoxy quinazoline and pharmaceutically acceptable acid addition salts thereof. The compounds are useful as antihypertensive agents.

Abstract: Described are antihypertensive agents selected from the class consisting of 2[4(tetrahydro-2-furoyl)-piperazino]-4-amino-6,7-dimethoxyquinazoline and 2-[4(tetrahydropyran-2-carbonyl)-piperazinyl]-4-amino-6,7-dimethoxyquinazo line, and pharmaceutically acceptable acid addition salts thereof. The compounds are highly water soluble and can be administered in time release form as well as parenterally, including intravenously.