Patents by Inventor Daniel Ansaldi

Daniel Ansaldi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • In-vivo reactive species imaging
    Patent number: 11040118
    Abstract: The disclosure features methods that include: administering to a subject a composition that includes particles, where each one of the particles features at least one targeting group that binds to a structural entity in the subject and at least one reacting group that reacts chemically with a reactive oxygen species in the subject, and where the particle emits luminescence when the reaction occurs; detecting the luminescence emission from the particles; and displaying an image of the subject showing locations of at least some reactive oxygen species in the subject based on the detected luminescence.
    Type: Grant
    Filed: November 7, 2018
    Date of Patent: June 22, 2021
    Assignee: Caliper Life Sciences, Inc.
    Inventors: Sunetra Ray, Daniel Ansaldi, Rajendra Singh
  • IN-VIVO REACTIVE SPECIES IMAGING
    Publication number: 20190070317
    Abstract: The disclosure features methods that include: administering to a subject a composition that includes particles, where each one of the particles features at least one targeting group that binds to a structural entity in the subject and at least one reacting group that reacts chemically with a reactive oxygen species in the subject, and where the particle emits luminescence when the reaction occurs; detecting the luminescence emission from the particles; and displaying an image of the subject showing locations of at least some reactive oxygen species in the subject based on the detected luminescence.
    Type: Application
    Filed: November 7, 2018
    Publication date: March 7, 2019
    Inventors: Sunetra Ray, Daniel Ansaldi, Rajendra Singh
  • In-vivo reactive species imaging
    Patent number: 10124072
    Abstract: The disclosure features methods that include: administering to a subject a composition that includes particles, where each one of the particles features at least one targeting group that binds to a structural entity in the subject and at least one reacting group that reacts chemically with a reactive oxygen species in the subject, and where the particle emits luminescence when the reaction occurs; detecting the luminescence emission from the particles; and displaying an image of the subject showing locations of at least some reactive oxygen species in the subject based on the detected luminescence.
    Type: Grant
    Filed: September 18, 2013
    Date of Patent: November 13, 2018
    Inventors: Sunetra Ray, Daniel Ansaldi, Rajendra Singh
  • Compositions and methods for in vivo evaluation of bioluminescence
    Patent number: 9486542
    Abstract: Compositions and methods are described for normalizing a bioluminescent signal in a live animal.
    Type: Grant
    Filed: January 27, 2015
    Date of Patent: November 8, 2016
    Assignee: Caliper Life Sciences
    Inventors: Stephen Oldfield, Daniel Ansaldi, Rajendra Singh, Ning Zhang
  • In vivo imaging of enzymatic activity
    Patent number: 9446151
    Abstract: Compositions and methods are described for detecting enzyme activity in a live organism (e.g., animal) are provided.
    Type: Grant
    Filed: April 13, 2012
    Date of Patent: September 20, 2016
    Assignee: Caliper Life Sciences, Inc.
    Inventors: Daniel Ansaldi, Kevin P. Francis, Rajendra Singh, Ning Zhang
  • COMPOSITIONS AND METHODS FOR IN VIVO EVALUATION OF BIOLUMINESCENCE
    Publication number: 20150143554
    Abstract: Compositions and methods are described for normalizing a bioluminescent signal in a live animal.
    Type: Application
    Filed: January 27, 2015
    Publication date: May 21, 2015
    Inventors: Stephen Oldfield, Daniel Ansaldi, Rajendra Singh, Ning Zhang
  • IN-VIVO REACTIVE SPECIES IMAGING
    Publication number: 20150079002
    Abstract: The disclosure features methods that include: administering to a subject a composition that includes particles, where each one of the particles features at least one targeting group that binds to a structural entity in the subject and at least one reacting group that reacts chemically with a reactive oxygen species in the subject, and where the particle emits luminescence when the reaction occurs; detecting the luminescence emission from the particles; and displaying an image of the subject showing locations of at least some reactive oxygen species in the subject based on the detected luminescence.
    Type: Application
    Filed: September 18, 2013
    Publication date: March 19, 2015
    Inventors: Sunetra Ray, Daniel Ansaldi, Rajendra Singh
  • IN VIVO IMAGING OF ENZYMATIC ACTIVITY
    Publication number: 20130101511
    Abstract: Compositions and methods are described for detecting enzyme activity in a live organism (e.g., animal) are provided.
    Type: Application
    Filed: April 13, 2012
    Publication date: April 25, 2013
    Inventors: Daniel Ansaldi, Kevin P. Francis, Rajendra Singh, Ning Zhang
  • Compositions and methods for in vivo evaluation of bioluminescence
    Publication number: 20110182823
    Abstract: Compositions and methods are described for normalizing a bioluminescent signal in a live animal.
    Type: Application
    Filed: September 16, 2010
    Publication date: July 28, 2011
    Inventors: Stephen Oldfield, Daniel Ansaldi, Rajendra Singh, Ning Zhang