Patents by Inventor Daniel B. Wall

Daniel B. Wall has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTIBODY QUANTITATION
    Publication number: 20100015652
    Abstract: The invention relates to a novel method for determining the amount of an antibody of interest in a biological sample. In one embodiment, the method of the invention is characterized in that it comprises at least a step of protein depletion of said biological sample by pepsin digestion to produce F(ab)2 fragments. In a preferred embodiment, one ore more peptides identifying the sequence of the antibody of interest is monitored using high-performance liquid chromatography with tandem mass spectrometry detection (HPLC-MS/MS).
    Type: Application
    Filed: December 20, 2007
    Publication date: January 21, 2010
    Inventors: Brian Walter Granda, Daniel B. Wall, Yingpi Karen Wang
  • Three dimensional protein mapping
    Patent number: 6931325
    Abstract: The present invention relates to multi-phase protein separation methods capable of resolving and characterizing large numbers of cellular proteins, including methods for efficiently facilitating the transfer of protein samples between separation phases. In particular, the present invention provides systems and methods for the generation of multi-dimensional protein maps. The present invention thus provides improved methods for the analysis of samples containing large numbers of proteins.
    Type: Grant
    Filed: April 26, 2002
    Date of Patent: August 16, 2005
    Assignee: Regents of the University of Michigan
    Inventors: Daniel B. Wall, David M. Lubman, Timothy Barder
  • Protein mapping
    Publication number: 20040010126
    Abstract: The present invention relates to multiphase protein separation methods capable of resolving large numbers of cellular proteins. The methods of the present invention provide protein profile maps for imaging and comparing protein expression patterns. The present invention provides alternatives to traditional 2-D gel separation methods for the screening of protein profiles.
    Type: Application
    Filed: October 1, 2001
    Publication date: January 15, 2004
    Applicant: The Regents of the University of Michigan
    Inventors: David M. Lubman, Timothy J. Barder, Daniel B. Wall, Stephen J. Parus, Maureen T. Kachman, Bathsheba E. Chong, Samir M. Hanash, David E. Misek, Robert Hinderer
  • Three dimensional protein mapping
    Publication number: 20030058239
    Abstract: The present invention relates to multi-phase protein separation methods capable of resolving and characterizing large numbers of cellular proteins, including methods for efficiently facilitating the transfer of protein samples between separation phases. In particular, the present invention provides systems and methods for the generation of multi-dimensional protein maps. The present invention thus provides improved methods for the analysis of samples containing large numbers of proteins.
    Type: Application
    Filed: April 26, 2002
    Publication date: March 27, 2003
    Applicant: The Regents of the University of Michigan
    Inventors: Daniel B. Wall, David M. Lubman, Tiimothy Barder
  • Protein separation and display
    Publication number: 20020098595
    Abstract: The present invention relates to multi-phase protein separation methods capable of resolving and characterizing large numbers of cellular proteins, including methods for efficiently facilitating the transfer of protein samples between separation phases. In particular, the present invention provides an automated system for the separation, identification, and characterization of protein samples. The present invention thus provides improved methods for the analysis of samples containing large numbers of proteins.
    Type: Application
    Filed: February 7, 2001
    Publication date: July 25, 2002
    Applicant: The Regents of the University of Michigan
    Inventors: David M. Lubman, Timothy J. Barder, Daniel B. Wall, Stephen J. Parus, Maureen T. Kachman, Bathsheba E. Chong, Robert C. North, Fang Yan