Patents by Inventor Daniel B. Werz

Daniel B. Werz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibodies for the detection of and vaccine against infections
    Patent number: 7901687
    Abstract: The present invention relates to conjugates of oligosaccharides of formula 1, wherein R is a linker to a carrier protein and optionally comprises up to three further saccharides, 5 and which are useful for vaccination, methods of synthesis of such conjugates, antibodies against this antigen, hybridoma producing monoclonal antibodies against this antigen, assays using these antibodies for the detection of B. anthracis spores and kits comprising these antibodies, and a vaccine for the prevention of B. anthracis infection comprising the conjugates of oligosaccharides of formula 1. Monoclonal antibodies 10 according to the invention selectively bind to B. anthracis, but not to related bacteria such as B. subtilis, B. cereus and other bacteria of this group such as B. thuringiensis.
    Type: Grant
    Filed: April 27, 2007
    Date of Patent: March 8, 2011
    Assignees: Eth Zurich, Schweizerisches Tropeninstitut
    Inventors: Daniel B. Werz, Peter H. Seeberger, Marco Tamborrini, Gerd Pluschke
  • Antibodies for the Detection of Bacillus Anthracis and Vaccine Against B. Anthracis Infections
    Publication number: 20090155299
    Abstract: The present invention relates to conjugates of oligosaccharides of formula 1, wherein R is a linker to a carrier protein and optionally comprises up to three further saccharides, 5 and which are useful for vaccination, methods of synthesis of such conjugates, antibodies against this antigen, hybridoma producing monoclonal antibodies against this antigen, assays using these antibodies for the detection of B. anthracis spores and kits comprising these antibodies, and a vaccine for the prevention of B. anthracis infection comprising the conjugates of oligosaccharides of formula 1. Monoclonal antibodies 10 according to the invention selectively bind to B. anthracis, but not to related bacteria such as B. subtilis, B. cereus and other bacteria of this group such as B. thuringiensis.
    Type: Application
    Filed: April 27, 2007
    Publication date: June 18, 2009
    Inventors: Daniel B. Werz, Peter H. Seeberger, Marco Tamborrini, Gerd Pluschke