Abstract: An eye-mountable device includes layer(s) of polymer material defining a body. The body includes a first side and a second side extending from a first end to a second end. The first side opposes the second side and curves inwardly toward the second side. The second side curves outwardly away from the first side. The body includes an anterior surface and a posterior surface extending from the first side to the second side and from the first end to the second end. The anterior side opposes the posterior side. The posterior surface has a concave shape. The device includes a substrate in the body including a mounting platform disposed proximally to a middle of the second side. The device includes, on the mounting platform, electronics that interact with a biological environment and monitor health-related information. The body may have a thickness profile that prevents the device from undesired movement.

Abstract: Systems and methods for monitoring medication adherence and compliance are provided. A medication monitoring system may include a medication container, a cover, and a beacon system. The beacon system may include a beacon that transmits a wireless signal when the cover is removed from the medication container. A method for monitoring medication adherence and compliance may include detecting when a cover of a medication container is removed from the medication container. The method may further include transmitting based on the detection, a signal from a beacon to a remote device, which indicates the opening of the medication container.

Abstract: An eye-mountable composition, an eye-mountable device and a method for making the eye-mountable device are disclosed. In one aspect, an eye-mountable composition is disclosed, which may include a silicone hydrogel having silicon-containing monomer-derived units and hydrophilic monomer-derived units, a non-silicone hydrogel having non-silicon-containing hydrophobic monomer-derived units and hydrophilic monomer-derived units, or an elastomer. The composition is biocompatible, does not adhere to ocular tissue, and has a modulus of elasticity of 0.2 MPa to 10 MPa. Also provided is an eye mountable device including an electronics platform embedded in an eye-mountable composition, and a method for fabricating the eye-mountable device.

Abstract: Systems and methods for monitoring medication adherence and compliance are provided. A medication monitoring system may include a medication container, a cover, and a beacon system. The beacon system may include a beacon that transmits a wireless signal when the cover is removed from the medication container. A method for monitoring medication adherence and compliance may include detecting when a cover of a medication container is removed from the medication container.

Abstract: Systems and methods for triggering a drug injection device are disclosed. One disclosed system for injecting a substance into a patient includes: a chamber comprising a propellant; a light source mechanically coupled to the chamber, wherein energy from the light source ignites the propellant; and a power source electrically coupled to the light source via a control circuit, wherein the control circuit applies power to activate the light source.

Abstract: Systems and methods for monitoring medication adherence and compliance are provided. A medication monitoring system may include a medication container, a cover, and a beacon system. The beacon system may include a beacon that transmits a wireless signal when the cover is removed from the medication container. A method for monitoring medication adherence and compliance may include detecting when a cover of a medication container is removed from the medication container. The method may further include transmitting based on the detection, a signal from a beacon to a remote device, which indicates the opening of the medication container.

Abstract: An eye-mountable device includes layer(s) of polymer material defining a body. The body includes a first side and a second side extending from a first end to a second end. The first side opposes the second side and curves inwardly toward the second side. The second side curves outwardly away from the first side. The body includes an anterior surface and a posterior surface extending from the first side to the second side and from the first end to the second end. The anterior side opposes the posterior side. The posterior surface has a concave shape. The device includes a substrate in the body including a mounting platform disposed proximally to a middle of the second side. The device includes, on the mounting platform, electronics that interact with a biological environment and monitor health-related information. The body may have a thickness profile that prevents the device from undesired movement.

Abstract: Systems and methods for monitoring medication adherence and compliance are provided. A medication monitoring system may include a medication container, a cover, and a beacon system. The beacon system may include a beacon that transmits a wireless signal when the cover is removed from the medication container. A method for monitoring medication adherence and compliance may include detecting when a cover of a medication container is removed from the medication container. The method may further include transmitting based on the detection, a signal from a beacon to a remote device, which indicates the opening of the medication container.

Abstract: The present disclosure provides an apparatus including a first chamber containing an eye-mountable device. The apparatus may also include a second chamber containing an aqueous solution. The apparatus may also include a membrane positioned between the first chamber and the second chamber. The membrane may be configured to rupture based on application of a force to the apparatus. The ruptured membrane may allow the aqueous solution to engage with the eye-mountable device. The apparatus may also include a lid to seal one or more of the first chamber and the second chamber.

Abstract: The present disclosure provides an apparatus including a first chamber containing an eye-mountable device. The apparatus may also include a second chamber containing an aqueous solution. The apparatus may also include a membrane positioned between the first chamber and the second chamber. The membrane may be configured to rupture based on application of a force to the apparatus. The ruptured membrane may allow the aqueous solution to engage with the eye-mountable device. The apparatus may also include a lid to seal one or more of the first chamber and the second chamber.

Abstract: The present disclosure provides an apparatus including a first chamber containing an eye-mountable device. The apparatus may also include a second chamber containing an aqueous solution. The apparatus may also include a membrane positioned between the first chamber and the second chamber. The membrane may be configured to rupture based on application of a force to the apparatus. The ruptured membrane may allow the aqueous solution to engage with the eye-mountable device. The apparatus may also include a lid to seal one or more of the first chamber and the second chamber.

Abstract: A casting mold is provided for forming a biomedical device including an ophthalmic device such as a contact lens. The casting mold includes an anterior mold section and a posterior mold section, wherein one of the mold sections includes a plurality of radially extending ribs and the remaining mold section includes an annular shoulder for engaging an outer end of the ribs to define a mold cavity.

Abstract: A method is provided of forming a biomedical device in a casting mold which has an anterior mold section and a posterior mold section, wherein one of the mold sections includes a plurality of radially extending ribs and the remaining mold section includes an annular shoulder for engaging an outer end of the ribs to define a mold cavity. The method includes engaging the mold sections along a peripheral seal of the mold cavity and a plurality of circumferentially spaced contact points on a shoulder of one of the mold sections. Cured excess material bonds to the ribs of the one mold section and provides repeatable retention and location of the excess material after formation of the biomedical device.

Abstract: A casting mold is provided for forming a biomedical device including an ophthalmic device such as a contact lens. The casting mold includes an anterior mold section and a posterior mold section, wherein one of the mold sections includes a plurality of radially extending ribs and the remaining mold section includes an annular shoulder for engaging an outer end of the ribs to define a mold cavity.

Abstract: A method is provided of forming a biomedical device in a casting mold which has an anterior mold section and a posterior mold section, wherein one of the mold sections includes a plurality of radially extending ribs and the remaining mold section includes an annular shoulder for engaging an outer end of the ribs to define a mold cavity. The method includes engaging the mold sections along a peripheral seal of the mold cavity and a plurality of circumferentially spaced contact points on a shoulder of one of the mold sections. Cured excess material bonds to the ribs of the one mold section and provides repeatable retention and location of the excess material after formation of the biomedical device.

Abstract: An apparatus and method is provided for injection molding an ophthalmic lens mold section having an optical surface and a non-optical surface opposite the optical surface. The apparatus includes a non-optical tool assembly for forming the non-optical surface of the ophthalmic lens mold section. An optical tool assembly is in opposed relation to the non-optical tool assembly and together therewith forms a mold cavity for forming the ophthalmic lens mold section. In the preferred embodiment, the optical tool assembly includes a rotatably mounted core member and an optical insert removably secured the core member. The optical insert has an optical molding surface for forming an optical surface of the ophthalmic lens mold section opposite the non-optical surface thereof. A locking mechanism having, in a preferred embodiment, a locking pin selectively movable between a first position wherein the pin allows rotation of the core member and a second position wherein the pin prevents the core member from rotation.