Abstract: The present invention relates to a drive mechanism of a drug delivery device for setting and dispensing of a dose of a medicament, the mechanism comprising: a housing (20), a piston rod (120) to operably engage with a piston (14) of a cartridge (12) to displace the piston (14) in a distal direction (1), a rotatable member (80) arranged on an axially extending axis of rotation (4) in the housing (20), said rotatable member (80) being rotatable in a dose incrementing direction (5) against the action of a spring element (78) and being operably engageable with the piston rod (120) during dose dispensing, a clutch member (150) comprising at least one radially displaceable clutch element (153) to engage with a rim (82) of the rotatable member (80) with variably adjustable strength.

Abstract: The present invention relates to a drive mechanism of a drug delivery device for setting and dispensing of a dose of a medicament, the mechanism comprising: a housing (20), a piston rod (120) to operably engage with a piston (14) of a cartridge (12) to displace the piston (14) in a distal direction (1), a rotatable member (80) arranged on an axially extending axis of rotation (4) in the housing (20), said rotatable member (80) being rotatable in a dose incrementing direction (5) against the action of a spring element (78) and being operably engageable with the piston rod (120) during dose dispensing, a clutch member (150) comprising at least one radially displaceable clutch element (153) to engage with a rim (82) of the rotatable member (80) with variably adjustable strength.

Abstract: This disclosure relates to a drive mechanism for a drug delivery device and to a respective drug delivery device. The drive mechanism includes an elongated housing extending in an axial direction, an actuation member rotatably supported on the housing for setting of the dose. The drive mechanism further includes a last dose sleeve directly rotatably engaged with the actuation member and having at least one stop and a last dose member threadedly engaged with the last dose sleeve. The last dose member is further rotatably fixed to the housing and is operable to engage with the at least one stop to limit a rotation of the last dose sleeve.

Abstract: A drive mechanism of a drug delivery device for setting and dispensing of a dose of a medicament includes a housing, a piston rod, a dose indicating member with a dose size information thereon, and a drive wheel. The piston rod engages with a piston of a cartridge for displacing the piston in a distal direction. The dose indicating member is connected to a spring element and is rotatable in a dose incrementing direction against the action of the spring element for setting a dose. The drive wheel is operably engaged with the piston rod for displacing the piston rod in the distal direction for dose dispensing. The dose indicating member is engageable with the drive wheel during dose dispensing to transfer a force to the drive wheel when driven by the relaxing spring element in a dose decrementing direction.

Abstract: A drive mechanism of a drug delivery device for dispensing of a dose of a medicament includes a housing extending in an axial direction, and a piston rod to operably engage with a piston of a cartridge to displace the piston in an axial distal direction. The drive mechanism further includes a last dose sleeve rotatably supported in the housing and being selectively engageable with a dose setting mechanism for setting of a dose, and a last dose member threadedly engaged to the housing, rotatably locked to the last dose sleeve and axially displaceable relative to the last dose sleeve.

Abstract: The present invention relates to a drive mechanism of a drug delivery device for dispensing of a dose of a medicament, the mechanism comprising: —a housing (20), —a piston rod (120) extending in an axial direction (1, 2) to operably engage with a piston (14) of a cartridge (12), —a drive sleeve (90) rotatably supported in the housing (20), at least partially enclosing the piston rod (120), the drive sleeve (90) is operably releasable from the piston rod (120) for setting of a dose and the drive sleeve (90) is operably engageable with the piston rod (120) for dispensing of the dose, —a dose limiting member (130) threadedly engaged with the drive sleeve (90), rotatably locked to the housing (20) and being displaceable in axial direction (1, 2) in response to a rotation of the drive sleeve (90) relative to the piston rod (120), —at least one stop member (124) provided on the piston rod (120) to engage with the dose limiting member (130) for impeding a further displacement of the drive sleeve (90) relative to the

Abstract: A drug delivery device for setting and dispensing of a dose of a medicament includes a housing extending in an axial direction and a piston rod to operably engage with a piston of a cartridge to displace the piston in a distal axial direction. The drug delivery device further includes a drive spindle operably engageable with the piston rod during dose dispensing and a drive member axially displaceable relative to the drive spindle against the action of a spring element during dose setting and being threadedly engaged with the drive spindle to form a spindle gear.

Abstract: A drive mechanism of a drug delivery device for dispensing of a dose of a medicament includes a housing extending in an axial direction, a piston rod to operably engage with a piston of a cartridge to displace the piston in an axial distal direction, and a drive sleeve extending in the axial direction and being rotatable in a dose incrementing direction against the action of a spring enclosing at least an axial portion of the drive sleeve. The drive mechanism further includes a dose limiting member threadedly engaged with the drive sleeve, rotatably locked to the housing and at least partially extending radially between the drive sleeve and the spring, and at least one stop located on at least one of dose limiting member and drive sleeve for limiting an axial displacement of the dose limiting member relative to the drive sleeve.

Abstract: A drug delivery device for dispensing of a dose of a medicament includes a housing extending in an axial direction and a piston rod to operably engage with a piston of a cartridge to displace the piston in an axial distal direction. The drug delivery device includes a dose indicating mechanism including a first spool and a second spool rotatably supported in the housing and a dose indicating tape coiled onto at least the second spool and fixed with an end to an outer circumference of the first spool. The first and second spools are oriented substantially parallel to each other and substantially parallel to the piston rod.

Abstract: The present invention relates to a drive mechanism for a drug delivery device for dispensing of a dose of a medicament, and to a respective drug delivery device, wherein the drive mechanism comprises: —an elongated housing (30) extending in an axial direction (1, 2), —a piston rod (80) to operably engage with a piston (16) of a cartridge (14) to displace the piston (16) in axial distal direction (1), —a drive sleeve (60) extending in axial direction (1, 2) and being rotatably supported in the housing (30), —a dose setting member (40) rotatably supported on a side wall portion (31) of the housing (30) and being rotatable with respect to an axis (41) extending in radial direction (r), —wherein the drive sleeve (60) is operably releasable from the piston rod (80) and rotatably engageable with the dose setting member (40) for setting of the dose.

Abstract: A drive mechanism for a drug delivery device includes an elongated housing extending in an axial direction and a piston rod to operably engage with a piston of a cartridge to displace the piston in an axial distal direction. A drive sleeve is rotatably supported in the housing, operably releasable from the piston rod for setting of a dose, and operably engageable with the piston rod for dispensing of the dose. A dose limiting member is engaged with the drive sleeve and engaged with the piston rod in such a way that it is displaced in axial direction relative to the drive sleeve when the drive sleeve rotates relative to the piston rod during a dose setting procedure. At least one stop is configured to engage with the dose limiting member for limiting the axial displacement of the dose limiting member during the dose setting procedure and to impede further displacement of the drive sleeve relative to the piston rod.

Abstract: A drug delivery device for dispensing a dose of a medicament includes an elongated housing extending in an axial direction, and a piston rod to operably engage with a piston of a cartridge to displace the piston in a distal axial direction. The drug delivery device further includes a drive sleeve extending in an axial direction and being rotatable against the action of a spring during a dose setting procedure and a dispensing sleeve rotatably engaged with the piston rod and being displaceable in an axial direction relative to the drive sleeve to engage with the drive sleeve in a torque transmissive way during a dose dispensing procedure.

Abstract: The present invention relates to a drive member of a drug delivery device for dispensing of a dose of a medicament, the mechanism comprising: a housing (30) extending in an axial direction (1, 2), a piston rod (90) to operably engage with a piston (16) of a cartridge (14) to displace the piston (16) in an axial distal direction (1), a dose indicating mechanism (130) comprising a first spool (140; 240) and a second spool (142; 242) rotatably supported in the housing (30), wherein first and second spools (140, 142; 240, 242) are oriented substantially parallel to each other and substantially parallel to the piston rod (90), a dose indicating tape (146; 246) coiled onto at least the second spool (142; 242) and fixed with an end to an outer circumference of the first spool (140; 240).

Abstract: The present invention relates to a drive mechanism of a drug delivery device for dispensing of a dose of a medicament, the mechanism comprising:—a housing (30, 120) extending in an axial direction (1, 2),—a piston rod (90) to operably engage with a piston (16) of a cartridge (14) to displace the piston (16) in an axial distal direction (1),—a drive sleeve (40) extending in axial direction (1, 2) and being rotatable in a dose incrementing direction (4) against the action of a spring (48) enclosing at least an axial portion of the drive sleeve (40),—a dose limiting member (110) threadedly engaged with the drive sleeve (40), rotatably locked to the housing (30, 120) and at least partially extending radially between the drive sleeve (40) and the spring (48),—at least one stop (44, 47, 113, 114) located on at least one of dose limiting member (110) and drive sleeve (40) for limiting an axial displacement of the dose limiting member (110) relative to the drive sleeve (40).

Abstract: The present invention relates to a drive mechanism of a drug delivery device for dispensing of dose of a medicament, the mechanism comprising: —an elongated housing (30) extending in an axial direction (1, 2), —a piston rod (80) to operably engage with a piston (16) of a cartridge (14) to displace the piston (16) in a distal axial direction (1), —a drive sleeve (50) extending in axial direction (1, 2) and being rotatable against the action of a spring (68) during a dose setting procedure, —a dispensing sleeve (70) rotatably engaged with the piston rod (80) and being displaceable in axial direction (1, 2) relative to the drive sleeve (50) to engage with the drive sleeve (50) in a torque transmissive way during a dose dispensing procedure.

Abstract: The present invention relates to a drive mechanism for a drug delivery device and to a respective drug delivery device, wherein the drive mechanism comprises: —an elongated housing (20) extending in an axial direction (1, 2), a piston rod (70) to operably engage with a piston (16) of a cartridge (14) to displace the piston (16) in an axial distal direction (1), —a drive sleeve (50) rotatably supported in the housing (20) and being operably releasable from the piston rod (70) for setting of a dose and being operably engageable with the piston rod (70) for dispensing of the dose, —a dose limiting member (60) engaged with the drive sleeve (50) and engaged with the piston rod (70) in such a way, that it is displaced in axial direction (1, 2) relative to the drive sleeve (50) when the drive sleeve (50) rotates relative to the piston rod (70) during a dose setting procedure, and at least one stop (42, 56; 78) to engage with the dose limiting member (60) for limiting the axial displacement of the dose limiting membe

Abstract: Handheld drug injection device (10) for setting and dispensing of a dose of a medicament, having a housing (20) extending in an axial direction (1, 2) and a dose setting and drive mechanism (3) comprising: —a rotatable dose setting member (50) in a sidewall of the housing and engaging two dose indicating wheels (54,56), —a drive member (70) axially displaceable relative to a drive spindle (80) and the housing against the action of a spring element (78) during dose setting and having a sleeve-shaped part (72) being threadedly engaged with the drive spindle (80) to form a spindle gear, and having a rack portion (71) engaged with a gear wheel (58) of the dose setting member, —the drive spindle (80) being linked on its proximal end to a ratchet mechanism (140,150) which is releasable via an axially shiftable trigger button (40) for dose dispensing, and on its distal end via a pinion (86) to a —drive sleeve (90), the latter being axially shiftable to form a clutch for engagement with —a threaded piston rod (120),

Abstract: The present invention relates to a drive mechanism of a drug delivery device for setting and dispensing of a dose of a medicament, the mechanism comprising: a housing (20), a piston rod (120) to operably engage with a piston (14) of a cartridge (12) to displace the piston (14) in a distal direction (1), a rotatable member (80) arranged on an axially extending axis of rotation (4) in the housing (20), said rotatable member (80) being rotatable in a dose incrementing direction (5) against the action of a spring element (78) and being operably engageable with the piston rod (120) during dose dispensing, a clutch member (150) comprising at least one radially displaceable clutch element (153) to engage with a rim (82) of the rotatable member (80) with variably adjustable strength.

Abstract: The present invention relates to a drive mechanism for a drug delivery device for dispensing of a dose of a medicament, and to a respective drug delivery device, wherein the drive mechanism comprises: an elongated housing (30) extending in an axial direction (1, 2), a piston rod (80) to operably engage with a piston (16) of a cartridge (14) to displace the piston (16) in axial distal direction (1), a drive sleeve (60) extending in axial direction (1, 2) and being rotatably supported in the housing (30), a dose setting member (40) rotatably supported on a side wall portion (31) of the housing (30) and being rotatable with respect to an axis (41) extending in radial direction (r), wherein the drive sleeve (60) is operably releasable from the piston rod (80) and rotatably engageable with the dose setting member (40) for setting of the dose.

Abstract: The present invention relates to a drive mechanism of a drug delivery device for setting and dispensing of a dose of a medicament, the mechanism comprising: —a housing (20), —a piston rod (120) to operably engage with a piston (14) of a cartridge (12) for displacing the piston (14) in a distal direction (1), —a dose indicating member (40) with a dose size information (48) thereon, connected to a spring element (100) and being rotatable in a dose incrementing direction (5) against the action of the spring element (100) for setting of a dose, —a drive wheel (130) operably engaged with the piston rod (120) for displacing the piston rod (120) in distal direction (1) for dose dispensing, —wherein the dose indicating member (40) is engageable with the drive wheel (130) during dose dispensing to transfer a driving force to the drive wheel (130) when driven by the relaxing spring element (100) in a dose decrementing direction (6).