Patents by Inventor Daniel BODEN

Daniel BODEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hepatitis B virus (HBV) vaccines and uses thereof
    Patent number: 11725194
    Abstract: Polynucleotides encoding hepatitis B virus (HBV) core antigen and polymerase antigen, and related combinations are described. Also described are vectors, such as DNA plasmids or viral vectors, expressing the HBV core and polymerase antigens, and immunogenic compositions containing the expression vectors. Methods of inducing an immune response against HBV or treating a HBV-induced disease, particularly in individuals having chronic HBV infection, using the immunogenic compositions are also described.
    Type: Grant
    Filed: May 19, 2021
    Date of Patent: August 15, 2023
    Inventors: Daniel Boden, Helen Horton, Jean-Marc Edmond Fernand Marie Neefs, Soumitra Roy
  • Hepatitis B Virus (HBV) Vaccines and Uses Thereof
    Publication number: 20220324916
    Abstract: Polynucleotides encoding hepatitis B virus (HBV) surface antigens, and related combinations are described. Also described are vectors, such as DNA plasmids or viral vectors, expressing the HBV surface antigens, and immunogenic compositions containing the expression vectors. Methods of inducing an immune response against HBV or treating an HBV-induced disease, particularly in individuals having chronic HBV infection, using the immunogenic compositions are also described.
    Type: Application
    Filed: June 18, 2020
    Publication date: October 13, 2022
    Inventors: Helen Horton, Daniel Boden
  • SELF-REPLICATING RNA MOLECULES FOR HEPATITIS B VIRUS (HBV) VACCINES AND USES THEREOF
    Publication number: 20220313815
    Abstract: Self-replicating RNA molecules encoding hepatitis B virus (HBV) vaccines are described. Methods of inducing an immune response against HBV or treating an HBV-induced disease, particularly in individuals having chronic HBV infection, using the disclosed self-replicating RNA molecules are also described. Kits comprising the disclosed self-replicating RNA molecules are also described.
    Type: Application
    Filed: June 19, 2020
    Publication date: October 6, 2022
    Inventors: Helen HORTON, Daniel BODEN
  • LIPID NANOPARTICLE OR LIPOSOME DELIVERY OF HEPATITIS B VIRUS (HBV) VACCINES
    Publication number: 20220305108
    Abstract: Pharmaceutical compositions containing hepatitis B virus (HBV) vaccines and lipids are described. Methods of inducing an immune response against HBV or treating an HBV-induced disease, particularly in individuals having chronic HBV infection, using the disclosed pharmaceutical compositions are also described.
    Type: Application
    Filed: June 19, 2020
    Publication date: September 29, 2022
    Inventors: Helen HORTON, Ian STRICKLAND, Daniel BODEN
  • CARBOHYDRATE NANOCARRIER DELIVERY OF HEPATITIS B VIRUS (HBV) VACCINES
    Publication number: 20220305118
    Abstract: Pharmaceutical compositions containing hepatitis B virus (HBV) vaccines and carbohydrate polymers are described. Methods of inducing an immune response against HBV or treating an HBV-induced disease, particularly in individuals having chronic HBV infection, using the disclosed pharmaceutical compositions are also described.
    Type: Application
    Filed: June 19, 2020
    Publication date: September 29, 2022
    Inventors: Helen HORTON, Ian STRICKLAND, Daniel BODEN
  • ARENAVIRUS VECTORS FOR HEPATITIS B VIRUS (HBV) VACCINES AND USES THEREOF
    Publication number: 20220226467
    Abstract: Arenavirus vectors encoding hepatitis B virus (HBV) vaccines are described. Methods of inducing an immune response against HBV or treating an HBV-induced disease, particularly in individuals having chronic HBV infection, using the disclosed arenavirus vectors are also described.
    Type: Application
    Filed: June 18, 2020
    Publication date: July 21, 2022
    Inventors: Helen HORTON, Daniel BODEN
  • Methods and apparatus for the delivery of hepatitis B virus (HBV) vaccines
    Patent number: 11389531
    Abstract: Methods and apparatus for the reproducible, consistent and efficacious delivery of an HBV vaccine to a subject. The disclosure comprises apparatus for the controlled administration of the HBV vaccine through an orifice to the subject, a plurality of penetrating electrodes arranged with a predetermined spatial relationship relative to the orifice, and an electrical signal generator operatively connected to the electrodes.
    Type: Grant
    Filed: December 18, 2018
    Date of Patent: July 19, 2022
    Assignees: Janssen Sciences Ireland Unlimited Company, Ichor Medical Systems, Inc.
    Inventors: Daniel Boden, Helen Horton, Jean-Marc Edmond Fernand Marie Neefs, Soumitra Roy, Andrew W. Hannaman, Robert M. Bernard, Stephen A. Morse, Oliver Ruck, Adam Hartman, Thomas David Cox, Dorien De Pooter
  • HEPATITIS B VIRUS (HBV) VACCINES AND USES THEREOF
    Publication number: 20210269778
    Abstract: Polynucleotides encoding hepatitis B virus (HBV) core antigen and polymerase antigen, and related combinations are described. Also described are vectors, such as DNA plasmids or viral vectors, expressing the HBV core and polymerase antigens, and immunogenic compositions containing the expression vectors. Methods of inducing an immune response against HBV or treating a HBV-induced disease, particularly in individuals having chronic HBV infection, using the immunogenic compositions are also described.
    Type: Application
    Filed: May 19, 2021
    Publication date: September 2, 2021
    Inventors: Daniel BODEN, Helen HORTON, Jean-Marc Edmond Fernand Marie NEEFS, Soumitra ROY
  • Methods and Compositions for Inducing an Immune Response Against Hepatitis B Virus (HBV)
    Publication number: 20210268104
    Abstract: Provided herein are Modified Vaccinia Ankara (MVA) vectors and adenovirus vectors encoding HBV antigens. Also provided are methods of enhancing an immune response in a human subject by utilizing the MVA and adenovirus vectors encoding HBV antigens in a prime/boost regimen to the enhance the immune response in the human subject.
    Type: Application
    Filed: May 18, 2021
    Publication date: September 2, 2021
    Inventors: Daniel BODEN, Helen HORTON, Jean-Marc Edmond Fernand Marie NEEFS, Soumitra ROY, Jerôme Hubertina Henricus Victor CUSTERS, Roland Christian ZAHN, Markus KALLA
  • Use of a HIV derived accessory protein for the reactivation of latent HIV
    Patent number: 11098085
    Abstract: The present invention concerns the use of a protein comprising at least a HIV-derived accessory protein tat (trans-activator of transcription) or any derivative thereof for the reactivation of latent human immunodeficiency virus (HIV) from cells present in a HIV-infected patient.
    Type: Grant
    Filed: July 2, 2019
    Date of Patent: August 24, 2021
    Assignee: Janssen Sciences Ireland Unlimited Company
    Inventor: Daniel Boden
  • Hepatitis B virus (HBV) vaccines and uses thereof
    Patent number: 11021692
    Abstract: Polynucleotides encoding hepatitis B virus (HBV) core antigen and polymerase antigen, and related combinations are described. Also described are vectors, such as DNA plasmids or viral vectors, expressing the HBV core and polymerase antigens, and immunogenic compositions containing the expression vectors. Methods of inducing an immune response against HBV or treating a HBV-induced disease, particularly in individuals having chronic HBV infection, using the immunogenic compositions are also described.
    Type: Grant
    Filed: December 18, 2018
    Date of Patent: June 1, 2021
    Inventors: Daniel Boden, Helen Horton, Jean-Marc Edmond Fernand Marie Neefs, Soumitra Roy, Dorien De Pooter
  • Methods and compositions for inducing an immune response against Hepatitis B Virus (HBV)
    Patent number: 11020476
    Abstract: Provided herein are Modified Vaccinia Ankara (MVA) vectors and adenovirus vectors encoding HBV antigens. Also provided are methods of enhancing an immune response in a human subject by utilizing the MVA and adenovirus vectors encoding HBV antigens in a prime/boost regimen to the enhance the immune response in the human subject.
    Type: Grant
    Filed: December 18, 2018
    Date of Patent: June 1, 2021
    Inventors: Daniel Boden, Helen Horton, Jean-Marc Edmond Fernand Marie Neefs, Soumitra Roy, Jerôme Hubertina Henricus Victor Custers, Roland Christian Zahn, Markus Kalla
  • Use of a HIV derived accessory protein for the reactivation of latent HIV
    Publication number: 20190337992
    Abstract: The present invention concerns the use of a protein comprising at least a HIV-derived accessory protein tat (trans-activator of transcription) or any derivative thereof for the reactivation of latent human immunodeficiency virus (HIV) from cells present in a HIV-infected patient.
    Type: Application
    Filed: July 2, 2019
    Publication date: November 7, 2019
    Inventor: Daniel Boden
  • METHODS AND COMPOSITIONS FOR INDUCING AN IMMUNE RESPONSE AGAINST HEPATITIS B VIRUS (HBV)
    Publication number: 20190184011
    Abstract: Provided herein are Modified Vaccinia Ankara (MVA) vectors and adenovirus vectors encoding HBV antigens. Also provided are methods of enhancing an immune response in a human subject by utilizing the MVA and adenovirus vectors encoding HBV antigens in a prime/boost regimen to the enhance the immune response in the human subject.
    Type: Application
    Filed: December 18, 2018
    Publication date: June 20, 2019
    Inventors: Daniel BODEN, Helen HORTON, Jean-Marc Edmond Fernand Marie NEEFS, Soumitra ROY, Jerôme Hubertina Henricus Victor CUSTERS, Roland Christian ZAHN, Markus KALLA
  • METHODS AND APPARATUS FOR THE DELIVERY OF HEPATITIS B VIRUS (HBV) VACCINES
    Publication number: 20190184010
    Abstract: Methods and apparatus for the reproducible, consistent and efficacious delivery of an HBV vaccine to a subject. The disclosure comprises apparatus for the controlled administration of the HBV vaccine through an orifice to the subject, a plurality of penetrating electrodes arranged with a predetermined spatial relationship relative to the orifice, and an electrical signal generator operatively connected to the electrodes.
    Type: Application
    Filed: December 18, 2018
    Publication date: June 20, 2019
    Inventors: Daniel Boden, Helen Horton, Jean-Marc Edmond Fernand Marie Neefs, Soumitra Roy, Andrew W. Hannaman, Robert M. Bernard, Stephen A. Morse, Oliver Ruck, Adam Hartman, Thomas David Cox
  • HEPATITIS B VIRUS (HBV) VACCINES AND USES THEREOF
    Publication number: 20190185828
    Abstract: Polynucleotides encoding hepatitis B virus (HBV) core antigen and polymerase antigen, and related combinations are described. Also described are vectors, such as DNA plasmids or viral vectors, expressing the HBV core and polymerase antigens, and immunogenic compositions containing the expression vectors. Methods of inducing an immune response against HBV or treating a HBV-induced disease, particularly in individuals having chronic HBV infection, using the immunogenic compositions are also described.
    Type: Application
    Filed: December 18, 2018
    Publication date: June 20, 2019
    Inventors: Daniel Boden, Helen Horton, Jean-Marc Edmond Fernand Marie Neefs, Soumitra Roy
  • Use of a HIV derived accessory protein for the reactivation of latent HIV
    Publication number: 20170044218
    Abstract: The present invention concerns the use of a protein comprising at least a HIV-derived accessory protein tat (trans-activator of transcription) or any derivative thereof for the reactivation of latent human immunodeficiency virus (HIV) from cells present in a HIV-infected patient.
    Type: Application
    Filed: April 23, 2015
    Publication date: February 16, 2017
    Inventor: Daniel BODEN