Patents by Inventor Daniel Boutz

Daniel Boutz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SARS-COV-2 NEUTRALIZING ANTIBODIES AND USES THEREOF
    Publication number: 20240327503
    Abstract: Provided herein are antibodies and antibody fragments that bind to SARS-COV-2 spike protein. Methods of using these antibodies in in vitro methods are provided. Methods of using these antibodies in vivo to treat or prevent SARS-COV-2 infections are also provided.
    Type: Application
    Filed: March 11, 2022
    Publication date: October 3, 2024
    Inventors: Jimmy Dale GOLLIHAR, Jule GOIKE, Ching-Lin HSIEH, Andrew P. HORTON, Elizabeth GARDNER, Daniel BOUTZ, Andrew ELLINGTON, Edward MARCOTTE, Jason S. MCLELLAN, George GEORGIOU, Gregory C. IPPOLITO
  • Proteomic identification of antibodies
    Patent number: 10175249
    Abstract: Methods and compositions for identification of candidate antigen-specific variable regions as well as generation of antibodies or antigen-binding fragments that could have desired antigen specificity are provided. For example, in certain aspects, methods for determining amino acid sequences of serum antibody CDR3 and abundancy levels are described. In some aspects, methods for determining nucleic acid sequences of antibody variable region sequences and the frequency thereof in biological samples are provided. Furthermore, the invention provides methods for identification and generation of antibodies or antigen-binding fragments that comprise highly-represented CDR domains.
    Type: Grant
    Filed: September 25, 2015
    Date of Patent: January 8, 2019
    Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Jason Lavinder, Daniel Boutz, Yariv Wine, Edward M. Marcotte, George Georgiou
  • PROTEOMIC IDENTIFICATION OF ANTIBODIES
    Publication number: 20160146830
    Abstract: Methods and compositions for identification of candidate antigen-specific variable regions as well as generation of antibodies or antigen-binding fragments that could have desired antigen specificity are provided. For example, in certain aspects, methods for determining amino acid sequences of serum antibody CDR3 and abundancy levels are described. In some aspects, methods for determining nucleic acid sequences of antibody variable region sequences and the frequency thereof in biological samples are provided. Furthermore, the invention provides methods for identification and generation of antibodies or antigen-binding fragments that comprise highly-represented CDR domains.
    Type: Application
    Filed: September 25, 2015
    Publication date: May 26, 2016
    Inventors: Jason LAVINDER, Daniel BOUTZ, Yariv WINE, Edward M. MARCOTTE, George GEORGIOU
  • RAPID ISOLATION OF MONOCLONAL ANTIBODIES FROM ANIMALS
    Publication number: 20160034639
    Abstract: Methods and compositions for identification of candicate antigen-specific variable regions as well as generation of antibodies or antigen-binding fragments that could have desired antigen specificity are provided. For example, in certain aspects methods for determining amino acid sequences of serum antibody CDR and abundancy level are described. In some aspects, methods for determining nucleic acid sequences of antibody variable region sequences and frequency are provided. Furthermore, the invention provides methods for identification and generation of antibody or antigen-binding fragments that comprise highly-represented CDR.
    Type: Application
    Filed: July 27, 2015
    Publication date: February 4, 2016
    Inventors: Sai REDDY, Xin GE, Jason LAVINDER, Daniel BOUTZ, Andrew D. ELLINGTON, Edward M. MARCOTTE, George GEORGIOU
  • Rapid isolation of monoclonal antibodies from animals
    Patent number: 9090674
    Abstract: Methods and compositions for identification of candidate antigen-specific variable regions as well as generation of antibodies or antigen-binding fragments that could have desired antigen specificity are provided. For example, in certain aspects methods for determining amino acid sequences of serum antibody CDR and abundancy level are described. In some aspects, methods for determining nucleic acid sequences of antibody variable region sequences and frequency are provided. Furthermore, the invention provides methods for identification and generation of antibody or antigen-binding fragments that comprise highly-represented CDR.
    Type: Grant
    Filed: May 17, 2011
    Date of Patent: July 28, 2015
    Assignee: The Board of Regents of The University of Texas System
    Inventors: Sai Reddy, Xin Ge, Jason Lavinder, Daniel Boutz, Andrew D. Ellington, Edward M. Marcotte, George Georgiou
  • Rapid Isolation of Monoclonal Antibodies from Animals
    Publication number: 20110312505
    Abstract: Methods and compositions for identification of candidate antigen-specific variable regions as well as generation of antibodies or antigen-binding fragments that could have desired antigen specificity are provided. For example, in certain aspects methods for determining amino acid sequences of serum antibody CDR and abundancy level are described. In some aspects, methods for determining nucleic acid sequences of antibody variable region sequences and frequency are provided. Furthermore, the invention provides methods for identification and generation of antibody or antigen-binding fragments that comprise highly-represented CDR.
    Type: Application
    Filed: May 17, 2011
    Publication date: December 22, 2011
    Inventors: Sai Reddy, Xin Ge, Jason Lavinder, Daniel Boutz, Andrew D. Ellington, Edward M. Marcotte, George Georgiou