Abstract: A container may be created, and a plurality of domain name system (DNS) configuration objects may be added to the container. The plurality of DNS configuration objects may comprise at least one of private DNS zones, outbound forwarding rules, DNS query log configurations, and firewall rule groups. The container may be associated with a plurality of private logical networks. The container may also be across a plurality of customer accounts. Based on the plurality of DNS configuration objects, a plurality of DNS operations associated with the plurality of private logical networks may be performed. The plurality of DNS operations may comprise at least one of DNS query resolution, DNS query outbound forwarding, configuring a query log, or configuring a firewall.

Abstract: Systems and methods are for domain name system (DNS) resolutions in heterogeneous network environments including a virtual private cloud (VPC). An administrator of a virtual private cloud (VPC) specifies rules identifying sources for resolving DNS resolution requests. The rules may include routing a request to a source outside the VPC such as to an on-premises DNS resolver through an outbound IP endpoint.

Abstract: Systems and methods are for domain name system (DNS) resolutions in heterogeneous network environments including a virtual private cloud (VPC). An administrator of a virtual private cloud (VPC) specifies rules identifying sources for resolving DNS resolution requests. The rules may include routing a request to a source outside the VPC such as to an on-premises DNS resolver through an outbound IP endpoint.

Abstract: Systems and methods are for domain name system (DNS) resolutions in heterogeneous network environments including a virtual private cloud (VPC). An administrator of a virtual private cloud (VPC) specifies rules identifying sources for resolving DNS resolution requests. The rules may include routing a request to a source outside the VPC such as to an on-premises DNS resolver through an outbound IP endpoint.

Abstract: Provided herein, in some aspects, are methods of administering to a subject a thymidine kinase substrate having a label and detecting presence or absence of the label as an indication of the presence of a polyomavirus (e.g., JCV and BK).

Abstract: The invention provides a compound of formula (I) or a salt or solvate thereof: wherein R1, n, X, Y and Z are as defined in the specification, and uses of such compounds. The compounds inhibit GlyT1 transporters and are useful in the treatment of certain neurological and neuropsychiatric disorders, including schizophrenia.

Abstract: Compounds of formula (I) or a pharmaceutically acceptable salt, solvate or prodrug thereof, are disclosed: wherein R1 is C1-6alkyl, haloC1-6alkyl, C2-6alkenyl, amino, monoC1-4alkylamino or diC1-4alkylamino; R2 and R3, which may be the same or different, are hydrogen, halogen, C1-6alkyl, haloC1-6alkyl, C1-4alkoxy, haloC1-4alkoxy, cyano, amino, monoC1-4alkylamino or diC1-4alkylamino; each R4, which may be the same or different, is C1-6alkyl, halogen, C1-6alkyl, haloC1-6alkyl, C1-4alkoxy, haloC1-4alkoxy, cyano, nitro, amino, monoC1-4alkylamino or diC1-4alkylamino; p is 0, 1 or 2; n is 1 or 2; R5 and R6, which may be the same or different, are hydrogen, halogen, C1-6alkyl, haloC1-6alkyl, C1-4alkoxy, haloC1-4alkoxy, cyano, amino, monoC1-4alkylamino or diC1-4alkylamino; and Het is thienyl, pyridyl, pyrimidinyl, pyridazinyl, pyrimidinyl, pyrazinyl, imidazolyl, pyrazolyl, pyrrolyl, quinolyl, thiazolyl or furyl, each of which may be substituted by one or more groups independently selected from the list consisting