Abstract: Described herein are crystalline forms of (R)-3-(2-(trans-4-(2-aminoethylamino)cyclohexyl)acetamido)-2-hydroxy-3,4-dihydro-2H-benzo[e][1,2]oxaborinine-8-carboxylic acid. In some embodiments, the crystalline forms are formulated for treating a subject in need thereof with a bacterial infection.

Abstract: A method for identifying an accumulation of ice on at least one rotor blade of a wind turbine includes a number of steps. First, operating and ambient conditions during operation of the wind turbine are determined. An electrical output of the wind turbine that is to be expected under the operating and ambient conditions is determined. An electrical output that is actually generated by the wind turbine is measured, and the expected electrical output of the wind turbine is compared with the electrical output actually generated by same. Depending on the result of the comparison, whether the at least one rotor blade is free of ice is determined with a high level of probability and vibrations of the at least one rotor blade are detected. Characteristic properties of the vibrations are detected and stored as a reference for the device for identifying an accumulation of ice, if, in the comparison, it was determined with a high level of probability that the at least one rotor blade is free of ice.

Abstract: Provided are implantable or surface mounted biomedical devices and related methods for interfacing with a target tissue. The devices have a substrate and device component supported by the substrate. The components of the device are specially configured and packaged to be ultra-thin and mechanically compliant. In particular, device thicknesses are less than 1 mm and have lateral dimensions between about 1 m and 10 mm, depending on the application. Delivery substrates may be incorporated to assist with device implantation and handling. The devices can be shaped to provide injection in a minimally invasive manner, thereby avoiding unnecessary tissue damage and providing a platform for long-term implantation for interfacing with biological tissue.

Abstract: A method for detecting mechanical damage to a rotor blade of a wind turbine includes measuring vibrations of the rotor blade and generating a frequency-dependent vibration signal. A value of the signal energy over a predetermined frequency range of the vibration signal is determined at each of a number of measuring times and the respectively determined signal energy values are evaluated with respect to time in order to detect mechanical damage.

Abstract: Provided are fully implantable soft medical devices and related methods. The devices comprise stretchable electronic devices between on an elastomeric substrate and an elastomeric super-state. Electronic components of the electronic device are configured to interface with tissue. Wireless power and control systems provide wireless power and control of the electronic components, thereby providing the fully implantable functionality. The devices may have a plurality of independently addressable electronic components, such as LEDs. In this manner, wireless control of a single implanted device may still provide multi-functional capabilities, including in a multiplexed configuration.

Abstract: A method for monitoring a state of a drive train of a wind power plant. The drive train including at least one component which is mechanically connected to a rotating element of the drive train and at least one acceleration sensor connected to the rotating element and located at a distance from a rotational axis of the drive train. The at least one acceleration sensor is configured to rotate about the rotational axis of the drive train at the distance. A signal of the at least one acceleration sensor is sensed in terms of its timing at least one rotational speed of the rotating element and is examined for interference frequencies which correspond to damage in the drive train.

Abstract: Provided are implantable or surface mounted biomedical devices and related methods for interfacing with a target tissue. The devices have a substrate and device component supported by the substrate. The components of the device are specially configured and packaged to be ultra-thin and mechanically compliant. In particular, device thicknesses are less than 1 mm and have lateral dimensions between about 1 ?m and 10 mm, depending on the application. Delivery substrates may be incorporated to assist with device implantation and handling. The devices can be shaped to provide injection in a minimally invasive manner, thereby avoiding unnecessary tissue damage and providing a platform for long-term implantation for interfacing with biological tissue.

Abstract: A method for monitoring a state of a drive train of a wind power plant. The drive train including at least one component which is mechanically connected to a rotating element of the drive train and at least one acceleration sensor connected to the rotating element and located at a distance from a rotational axis of the drive train. The at least one acceleration sensor is configured to rotate about the rotational axis of the drive train at the distance. A signal of the at least one acceleration sensor is sensed in terms of its timing at least one rotational speed of the rotating element and is examined for interference frequencies which correspond to damage in the drive train.

Abstract: A method for detecting mechanical damage to a rotor blade of a wind turbine includes measuring vibrations of the rotor blade and generating a frequency-dependent vibration signal. A value of the signal energy over a predetermined frequency range of the vibration signal is determined at each of a number of measuring times and the respectively determined signal energy values are evaluated with respect to time in order to detect mechanical damage.

Abstract: Antibodies with fully human variable regions against a specific antigen can be prepared by administering the antigen to a transgenic animal which has been modified to produce such antibodies in response to antigenic challenge, but whose endogenous loci have been disabled. Various subsequent manipulations can be performed to obtain either antibodies per se or analogs thereof.

Abstract: Fully human antibodies against a specific antigen can be prepared by administering the antigen to a transgenic animal which has been modified to produce such antibodies in response to antigenic challenge, but whose endogenous loci have been disabled. Various subsequent manipulations can be performed to obtain either antibodies per se or analogs thereof.

Abstract: Antibodies with fully human variable regions against a specific antigen can be prepared by administering the antigen to a transgenic animal which has been modified to produce such antibodies in response to antigenic challenge, but whose endogenous loci have been disabled. Various subsequent manipulations can be performed to obtain either antibodies per se or analogs thereof.

Abstract: Fully human antibodies against a specific antigen can be prepared by administering the antigen to a transgenic animal which has been modified to produce such antibodies in response to antigenic challenge, but whose endogenous loci have been disabled. Various subsequent manipulations can be performed to obtain either antibodies per se or analogs thereof.