Abstract: Compounds of formula (I): Are antithrombotic agents, having utility in a variety of therapeutic areas including the prevention and/or treatment of deep vein thrombosis (DVT) after surgery, major medical illness, paralysis, malignancy, prolonged immobilisation trauma, application of lower limb plaster casts, or fractures of the lower limbs or pelvis; recurrent DVT; DVT during pregnancy when there is a previous history thereof; reocclusion following thrombolytic therapy; chronic arterial obstruction; peripheral vascular disease; acute myocardial infarction; unstable angina; atrial fibrillation; thrombotic stroke; transient ischaemic attacks; disseminated intravascular coagulation; coagulation in extra-corporeal circuits; occlusion of aterio-venous shunts and blood vessel grafts (including coronary artery by-pass grafts); and restenosis and occlusion following angioplasty.

Abstract: The invention concerns novel compounds having defined structural formulae and methods of mutating a nucleic acid sequence, the method comprising replicating a template sequence in the presence of a nucleoside triphosphate analogue in accordance with the invention, so as to form non-identical copies of the template sequence comprising one or more nucleoside triphosphate analogue residues, and a kit for use in performing the method of the invention.

Abstract: An .times.86 based computer system that implements a firmware based boot process without an .times.86 BIOS that supports expansion devices coupled to the computer system, wherein the expansion devices include their own respective BIOS extensions. The computer system includes an .times.86 processor coupled to a volatile memory and a non-volatile memory via a bus. The non-volatile memory includes firmware which when executed by the processor cause the computer system to implement the boot process. The firmware initializes device drivers for the computer system and initializes an application programming interface for the device drivers. The firmware then initializes a compatibility component for interfacing with the device drivers, wherein the compatibility component is operable for translating accesses by a first software application to an .times.86 BIOS into corresponding accesses to the device drivers.

Abstract: A universal interface system for use with a data acquisition system including a data acquisition device such as a bar code scanner or scanner integrated terminal for providing digital data signals indicative of acquired data for transmission to a host device such as a computer, and a host device having host-specific input/output data format requirements. The universal interface system comprises universal data exchange means located in the data acquisition device for providing digital data signals in a universal data exchange format independent of the data format requirements of the host device; and a host interface cable coupled to the data acquisition device and to said host device, for transmitting acquired digital data from the data acquisition device to the host device, the interface cable comprising means for translating digital data from the universal data exchange format to the host-specific input/output data format requirements.

Abstract: An improved image intensifier tube has electrically operative components that include a photocathode having a photoemissive layer, a microchannel plate (MCP) having a conductive input surface and a conductive output surface, and a vacuum housing for retaining the photocathode, microchannel plate and a fiber optic inverter and screen within an evacuated environment. The fiber optic inverter has a circumferentially extending flange portion extending toward the housing to accommodate a sealing material which sealingly engages an inner surface of an output flange with the inverter flange portion to form an air impervious vacuum seal and where the output flange is supported by the fiber optic inverter flange portion. The improved intensifier includes a photocathode having a flat faceplate conductively engaging the photocathode along the entire surface of the faceplate.

Abstract: A novel class of antibiotics, designated bravomicins, is obtained by fermentation of a strain of Micromonospora polytrota. Six bioactive compounds, designated bravomicins A, B, C, D, E and F, are obtained and found to be useful in the treatment of a wide variety of bacterial diseases.

Abstract: A semi-retroreflective optical scanning system has an optical scanning element which directs a scanning light beam via a stationary holographic optical element in a scan path across indicia to be read. Light from the indicia is collected by an optical collector, such as a lens or a mirror, which focuses it onto a small optical detector via the scanning element. The field of view of the optical detector scans across the indicia in synchronization with the outgoing scanning beam from the holographic optical element. Since the incoming reflected light is not limited by the aperture of the scanning element, the signal-to-noise ratio remains high even when a small scanning element is used. In a further embodiment the light source, scanning element collector and detector are provided in a common plane, the collector and scanning element sharing a common optical axis and a light source being provided substantially off axis to allow reduction in the scanning element size.

Abstract: Compounds of formula (I), pharmaceutically acceptable salts thereof, and pharmaceutically acceptable solvates of either entity, wherein A is optionally monosaturated C.sub.1 -C.sub.4 alkylene optionaly monounsaturatred with C.sub.1 -C.sub.4 alkyl; B is C.sub.1 -C.sub.3 alkylene optionally substituted with C.sub.1 -C.sub.4 alkyl; R.sup.1 is N-amidino-4-piperidyl or 4-amidinophenyl; R.sup.2 is C.sub.4 -C.sub.12 alkyl; (C.sub.3 -C.sub.8 cycalkyl)C.sub.1 -C.sub.4 alkylene; optionally methylene-bridged C.sub.5 -C.sub.8 cycloalkyl optionally substituted with one to three C.sub.1 -C.sub.4 alkyl groups or with hydroxy; C.sub.5 -C.sub.8 alkenyl; C.sub.5 -C.sub.8 cycloalkenyl optionally subsituted with C.sub.1 -C.sub.4 alkyl; piperidyl N-substituted with C.sub.1 -C.sub.4 alkyl; tetrahydrothiopyranyl or tetrahydropyranyl; and R.sup.3 is H or C.sub.1 -C.sub.4 alkyl optionally substituted with C.sub.1 -C.sub.4 alkoxy or with hydroxy; or R.sup.2 and R.sup.

Abstract: A universal interface system for use with a data acquisition system including a data acquisition device such as a bar code scanner or scanner integrated terminal for providing digital data signals indicative of acquired data for transmission to a host device such as a computer, and a host device having host-specific input/output data format requirements. The universal interface system comprises universal data exchange means located in the data acquisition device for providing digital data signals in a universal data exchange format independent of the data format requirements of the host device; and a host interface cable coupled to the data acquisition device and to said host device, for transmitting acquired digital data from the data acquisition device to the host device, the interface cable comprising means for translating digital data from the universal data exchange format to the host-specific input/output data format requirements.

Abstract: A system for processing output signals of an electro-optical scanner adapted for reading a bar code indicia having parts of different light reflectivity and non bar code indicia adjacent the bar code on an article being scanned comprises a decoder for decoding content of signals input thereto and signal processing circuitry for receiving the scanner output signals and generating input signals for input to the decoder by deleting signals having non bar code indicia content from the received scanner output signals by examining characteristics of the received scanner output signals. The signal processing circuitry is adapted to generate input signals for input to the decoder for bar code indicia of respective different bar code symbologies. The signal processing circuitry includes deletion circuitry for deleting, from the received scanner output signals, signals having less time duration than a predetermined time duration.

Abstract: Compounds of formula (I), pharmaceutically acceptable salts thereof, and pharmaceutically acceptable solvates (including hydrates) of either entity, wherein R.sup.1 is (a) R.sup.2 is R.sup.3 R.sup.4 C(OH)A; V is C.dbd.O or CH.sub.2 ; W is O or NR.sup.5 ; R.sup.3 and R.sup.4 are each independently selected from H and C.sub.1 -C.sub.4 alkyl; or, together with the carbon atom to which they are attached, form a 4- or 5-membered carbocyclic ring; R.sup.5 is H, benzyl, C.sub.1 -C.sub.5 alkanoyl or SO.sub.2 (C.sub.1 -C.sub.4)alkyl; A is C.sub.2 -C.sub.3 alkylene; m is 0 or 1; and n is 0 or 1; with the provisos that when n is 1 and V is C.dbd.O then W is NH, and when n is 1 and V is CH.sub.2 then W is O; are selective 5-HT.sub.1 -like agonists useful in the treatment of, inter alia, migraine, cluster headache, chronic paroxysmal hemicrania and headache associated with vascular disorders.

Abstract: A sharps container includes a disposable open topped receptacle having a lid with an elongated opening therethrough and a closure flap pivotally supported adjacent the opening for pivotal movement between positions for opening and closing the opening. The closure flap is self-closing, being biased to the closed position. The disposable receptacle may be supported within a reusable cabinet having upright spaced-apart end walls which extend upwardly above the lid of the receptacle. A handle on the exterior side of at least one wall is coupled to the closure flap for opening and closing the flap in response to turning movement of the handle. The raised container end walls shield the hand of an operator on the handle from sharps being inserted into the container opening.