Patents by Inventor Daniel Burgess
Daniel Burgess has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11773388Abstract: The present disclosure provides a method for enrichment of at least one target nucleic acid in a library of nucleic acids. A first oligonucleotide is hybridized to a target nucleic acid in library of nucleic acids having first and second adapters. The hybridized first oligonucleotide is extended with a first polymerase, thereby producing a first primer extension complex including the target nucleic acid and the extended first oligonucleotide. The first primer extension complex is captured, enriched relative to the library of nucleic acids, and a second oligonucleotide is hybridized to the target nucleic acid. The hybridized second oligonucleotide is extended with a second polymerase, thereby producing a second primer extension complex including the target nucleic acid and the extended second oligonucleotide, and further liberating the extended first oligonucleotide from the first primer extension complex.Type: GrantFiled: June 22, 2020Date of Patent: October 3, 2023Assignees: Roche Sequencing Solutions, Inc., Kapa Biosystems, Inc.Inventors: Daniel Burgess, Brian Christopher Godwin, Alexander Lovejoy, Bronwen Miller, Jo-Anne Elizabeth Penkler, Joseph Platzer
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Publication number: 20230250476Abstract: In one aspect of the present disclosure is a targeted sequencing workflow where an input sample comprising a sufficient quantity of genomic material is provided such minimal or no amplification cycles are utilized prior to sequencing.Type: ApplicationFiled: April 6, 2023Publication date: August 10, 2023Inventors: Nelson R. Alexander, Daniel Burgess, Heidi J. Rosenbaum, Stacey Stanislaw
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Patent number: 11649492Abstract: In one aspect of the present disclosure is a targeted sequencing workflow where an input sample comprising a sufficient quantity of genomic material is provided such minimal or no amplification cycles are utilized prior to sequencing.Type: GrantFiled: July 13, 2018Date of Patent: May 16, 2023Assignees: Roche Sequencing Solutions, Inc., Ventana Medical Systems, Inc.Inventors: Nelson R Alexander, Daniel Burgess, Heidi J Rosenbaum, Stacey Stanislaw
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Publication number: 20230039014Abstract: The present disclosure is directed to automated systems including a microfluidic chip having one or more independently operable processing conduits. In some embodiments, the automated systems are suitable for use in sample cleanup and/or target enrichment processes, such as sample cleanup and/or target enrichment processes conducted prior to sequencing.Type: ApplicationFiled: January 21, 2021Publication date: February 9, 2023Inventors: Yann Astier, Daniel Burgess, Ulrich Schlecht, Jaeyoung Yang
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Patent number: 11155853Abstract: The present disclosure provides a system and method for depleting target nucleic acids from a nucleic acid sample. In one aspect, a kit according to the present disclosure includes a plurality of DNA probes. Each of the DNA probes is hybridizable to form a heteroduplex with at least one of a plurality of target RNA transcripts in a nucleic acid sample. The number of unique target RNA transcripts hybridized by the plurality of DNA probes is at least three. The kit further includes an enzyme having RNA-DNA hybrid ribonucleotidohydrolase activity, where degrades at least the RNA portion of the heteroduplex.Type: GrantFiled: October 3, 2019Date of Patent: October 26, 2021Assignee: Roche Sequencing Solutions, Inc.Inventors: Venera Bouriakov, Daniel Burgess
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Publication number: 20200392483Abstract: The present disclosure provides a method for enrichment of at least one target nucleic acid in a library of nucleic acids. A first oligonucleotide is hybridized to a target nucleic acid in library of nucleic acids having first and second adapters. The hybridized first oligonucleotide is extended with a first polymerase, thereby producing a first primer extension complex including the target nucleic acid and the extended first oligonucleotide. The first primer extension complex is captured, enriched relative to the library of nucleic acids, and a second oligonucleotide is hybridized to the target nucleic acid. The hybridized second oligonucleotide is extended with a second polymerase, thereby producing a second primer extension complex including the target nucleic acid and the extended second oligonucleotide, and further liberating the extended first oligonucleotide from the first primer extension complex.Type: ApplicationFiled: June 22, 2020Publication date: December 17, 2020Inventors: Daniel Burgess, Brian Christopher Godwin, Alexander Lovejoy, Bronwen Miller, Jo-Anne Elizabeth Penkler, Joseph Platzer
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Patent number: 10820959Abstract: A system for charging an onboard battery of a medical device prior to use of the medical device may include a package configured to accommodate the medical device therein. A power source may be disposed relative to the package and may be capable of charging the onboard battery of the medical device prior to use of the medical device. The system may be capable of being subjected to a sterilization process with the power source disposed within the second cavity. In some instances, the power source is uncharged during sterilization. In some cases, the power source is encapsulated or otherwise sealed during sterilization.Type: GrantFiled: November 15, 2019Date of Patent: November 3, 2020Assignee: BOSTON SCIENTIFIC SCIMED, INCInventors: Jan Weber, Daniel Burgess, Kathryn A. Johnson, James M. Peck
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Publication number: 20200078126Abstract: A system for charging an onboard battery of a medical device prior to use of the medical device may include a package configured to accommodate the medical device therein. A power source may be disposed relative to the package and may be capable of charging the onboard battery of the medical device prior to use of the medical device. The system may be capable of being subjected to a sterilization process with the power source disposed within the second cavity. In some instances, the power source is uncharged during sterilization. In some cases, the power source is encapsulated or otherwise sealed during sterilization.Type: ApplicationFiled: November 15, 2019Publication date: March 12, 2020Applicant: BOSTON SCIENTIFIC SCIMED, INC.Inventors: JAN WEBER, DANIEL BURGESS, KATHRYN A. JOHNSON, JAMES M. PECK
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Publication number: 20200032244Abstract: The present disclosure provides a method for enrichment of at least one target nucleic acid in a library of nucleic acids. A first oligonucleotide is hybridized to a target nucleic acid in library of nucleic acids having first and second adapters. The hybridized first oligonucleotide is extended with a first polymerase, thereby producing a first primer extension complex including the target nucleic acid and the extended first oligonucleotide. The first primer extension complex is captured, enriched relative to the library of nucleic acids, and a second oligonucleotide is hybridized to the target nucleic acid. The hybridized second oligonucleotide is extended with a second polymerase, thereby producing a second primer extension complex including the target nucleic acid and the extended second oligonucleotide, and further liberating the extended first oligonucleotide from the first primer extension complex.Type: ApplicationFiled: August 15, 2019Publication date: January 30, 2020Inventors: Daniel Burgess, Brian Christopher Godwin, Alexander Lovejoy, Bronwen Miller, Jo-Anne Elizabeth Penkler, Joseph Platzer, Martin Ranik
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Publication number: 20200024646Abstract: The present disclosure provides a system and method for depleting target nucleic acids from a nucleic acid sample. In one aspect, a kit according to the present disclosure includes a plurality of DNA probes. Each of the DNA probes is hybridizable to form a heteroduplex with at least one of a plurality of target RNA transcripts in a nucleic acid sample. The number of unique target RNA transcripts hybridized by the plurality of DNA probes is at least three. The kit further includes an enzyme having RNA-DNA hybrid ribonucleotidohydrolase activity, where degrades at least the RNA portion of the heteroduplex.Type: ApplicationFiled: October 3, 2019Publication date: January 23, 2020Inventors: Venera Bouriakov, Daniel Burgess
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Patent number: 10478259Abstract: A system for charging an onboard battery of a medical device prior to use of the medical device may include a package configured to accommodate the medical device therein. A power source may be disposed relative to the package and may be capable of charging the onboard battery of the medical device prior to use of the medical device. The system may be capable of being subjected to a sterilization process with the power source disposed within the second cavity. In some instances, the power source is uncharged during sterilization. In some cases, the power source is encapsulated or otherwise sealed during sterilization.Type: GrantFiled: June 9, 2017Date of Patent: November 19, 2019Assignee: BOSTON SCIENTIFIC SCIMED, INC.Inventors: Jan Weber, Daniel Burgess, Kathryn A. Johnson, James M. Peck
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Patent number: 10472666Abstract: The present disclosure provides a system and method for depleting target nucleic acids from a nucleic acid sample. In one aspect, a kit according to the present disclosure includes a plurality of DNA probes. Each of the DNA probes is hybridizable to form a heteroduplex with at least one of a plurality of target RNA transcripts in a nucleic acid sample. The number of unique target RNA transcripts hybridized by the plurality of DNA probes is at least three. The kit further includes an enzyme having RNA-DNA hybrid ribonucleotidohydrolase activity, where degrades at least the RNA portion of the heteroduplex.Type: GrantFiled: February 3, 2017Date of Patent: November 12, 2019Assignee: Roche Sequencing Solutions, Inc.Inventors: Venera Bouriakov, Daniel Burgess
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Publication number: 20190284602Abstract: The present disclosure provides a system and method for depleting target nucleic acids from a nucleic acid sample. In one aspect, a kit according to the present disclosure includes a plurality of DNA probes. Each of the DNA probes is hybridizable to form a heteroduplex with at least one of a plurality of target RNA transcripts in a nucleic acid sample. The number of unique target RNA transcripts hybridized by the plurality of DNA probes is at least three. The kit further includes an enzyme having RNA-DNA hybrid ribonucleotidohydrolase activity, where degrades at least the RNA portion of the heteroduplex.Type: ApplicationFiled: February 3, 2017Publication date: September 19, 2019Inventors: Venera Bouriakov, Daniel Burgess
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Publication number: 20180320229Abstract: In one aspect of the present disclosure is a targeted sequencing workflow where an input sample comprising a sufficient quantity of genomic material is provided such minimal or no amplification cycles are utilized prior to sequencing.Type: ApplicationFiled: July 13, 2018Publication date: November 8, 2018Inventors: Nelson R. Alexander, Daniel Burgess, Heidi J. Rosenbaum, Stacey Stanislaw
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Publication number: 20180223331Abstract: The present disclosure provides a system and method for depleting target nucleic acids from a nucleic acid sample. In one aspect, a kit according to the present disclosure includes a plurality of DNA probes. Each of the DNA probes is hybridizable to form a heteroduplex with at least one of a plurality of target RNA transcripts in a nucleic acid sample. The number of unique target RNA transcripts hybridized by the plurality of DNA probes is at least three. The kit further includes an enzyme having RNA-DNA hybrid ribonucleotidohydrolase activity, where degrades at least the RNA portion of the heteroduplex.Type: ApplicationFiled: February 3, 2017Publication date: August 9, 2018Inventors: Venera Bouriakov, Daniel Burgess
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Publication number: 20170354473Abstract: A system for charging an onboard battery of a medical device prior to use of the medical device may include a package configured to accommodate the medical device therein. A power source may be disposed relative to the package and may be capable of charging the onboard battery of the medical device prior to use of the medical device. The system may be capable of being subjected to a sterilization process with the power source disposed within the second cavity. In some instances, the power source is uncharged during sterilization. In some cases, the power source is encapsulated or otherwise sealed during sterilization.Type: ApplicationFiled: June 9, 2017Publication date: December 14, 2017Applicant: BOSTON SCIENTIFIC SCIMED, INC.Inventors: JAN WEBER, DANIEL BURGESS, KATHRYN A. JOHNSON, JAMES M. PECK
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Publication number: 20150141256Abstract: This invention relates generally to composition and methods for characterizing a methylome which comprises all or substantially all methylation states of a genome. In particular, a plurality of oligonucleotides, each representing nearly every possible methylation state of the cytosine position of each CG dinucleotide pair within a target nucleic acid of interest, and methods of using the plurality are provided herein.Type: ApplicationFiled: July 23, 2014Publication date: May 21, 2015Inventors: Daniel Burgess, Jeffrey Jeddeloh
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Publication number: 20070284148Abstract: A system for damping vibration in a drill string can include a valve assembly having a supply of a fluid, a first member, and a second member capable of moving in relation to first member in response to vibration of the drill bit. The first and second members define a first and a second chamber for holding the fluid. Fluid can flow between the first and second chambers in response to the movement of the second member in relation to the first member. The valve assembly can also include a coil or a valve for varying a resistance of the fluid to flow between the first and second chambers.Type: ApplicationFiled: April 19, 2007Publication date: December 13, 2007Inventors: Mark Wassell, William Turner, Daniel Burgess, Carl Perry
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Publication number: 20060243487Abstract: A preferred embodiment of a system for rotating and guiding a drill bit in an underground bore includes a drilling motor and a drive shaft coupled to drilling motor so that drill bit can be rotated by the drilling motor. The system further includes a guidance module having an actuating arm movable between an extended position wherein the actuating arm can contact a surface of the bore and thereby exert a force on the housing of the guidance module, and a retracted position.Type: ApplicationFiled: April 29, 2005Publication date: November 2, 2006Applicant: APS Technology, Inc.Inventors: William Turner, Carl Perry, Mark Wassell, Jason Barbely, Daniel Burgess, Martin Cobern
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Publication number: 20060243489Abstract: A system for damping vibration in a drill string can include a valve assembly having a supply of a fluid, a first member, and a second member capable of moving in relation to first member in response to vibration of the drill bit. The first and second members define a first and a second chamber for holding the fluid. Fluid can flow between the first and second chambers in response to the movement of the second member in relation to the first member. The valve assembly can also include a coil or a valve for varying a resistance of the fluid to flow between the first and second chambers.Type: ApplicationFiled: November 8, 2004Publication date: November 2, 2006Inventors: Mark Wassell, William Turner, Daniel Burgess, Carl Perry