Patents by Inventor Daniel Burkhoff
Daniel Burkhoff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20060111660Abstract: Disclosed is a conduit that provides a bypass around a stenosis or occlusion in a coronary artery. The conduit is adapted to be positioned in the myocardium to provide a passage for blood to flow from a heart chamber to a coronary artery, at a site distal to the blockage or stenosis in the coronary artery. The conduit has a one-way valve positioned therein to prevent the backflow of blood from the coronary artery into the heart chamber.Type: ApplicationFiled: December 15, 2005Publication date: May 25, 2006Inventors: Scott Wolf, Greg Furnish, Todd Hall, David Phelps, Peter Wilk, Nancy Briefs, William Santamore, Daniel Burkhoff
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Patent number: 6949080Abstract: A stent suitable for implantation in myocardial tissue to enhance perfusion therein may include a tubular member having first and second ends and a lumen. The first end of the stent may be configured to pierce myocardial tissue and the lumen may be configured to be placed in flow communication with a coronary vessel. The stent may further include a means for retaining the tubular member within the myocardial tissue. A method for implanting the stent may include positioning the first end of the stent at a desired implantation site and applying force to the second end of the stent to implant the stent within the myocardial tissue. The method may further include engaging the means for retaining with the myocardial tissue to retain the stent in position.Type: GrantFiled: August 15, 2002Date of Patent: September 27, 2005Assignee: Percardia, Inc.Inventors: Scott J. Wolf, Greg R. Furnish, Todd A. Hall, David Y. Phelps, Peter J. Wilk, Nancy Briefs, William Santamore, Daniel Burkhoff, Simon Furnish, Stephen Evans, Roger D. Kamm, Richard Renati, Gerald Melsky, Eun Bo Shim
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Publication number: 20040147869Abstract: Left ventricular conduits and related methods are disclosed for achieving bypass of a partially or completely occluded coronary artery. More broadly, conduits for allowing communication of bodily fluids from one portion of a patient's body to another and related methods are disclosed, including conduits for forming a blood flow path from a chamber of the heart to a vessel or from one vessel to another. In other embodiments, the conduits achieve a coronary artery bypass by allowing blood communication between the left ventricle and the coronary artery or between a proximal portion of the coronary artery and a distal portion of the coronary artery. The conduits may be placed completely through the heart wall or extend only partially therein. Conduits may take on a variety of configurations for allowing the control of blood flow therethrough, including curved or tapered shapes.Type: ApplicationFiled: October 9, 2003Publication date: July 29, 2004Applicant: Percardia, Inc.Inventors: Scott J. Wolf, Greg R. Furnish, Todd A. Hall, David Y. Phelps, Peter J. Wilk, Nancy A. Briefs, William Santamore, Daniel Burkhoff, Simon Furnish, Stephen Evans, Roger D. Kamm, Richard Renad, Gerald Melsky, Eun Bo Shim
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Patent number: 6752771Abstract: A method and device are disclosed for inflating an inflatable vest to assist the heart in patients suffering from heart failure. The inflation of the vest is synchronized with on-set of the systole phase of the heart, when the left ventricular compresses to force blood out of the heart and through the aorta. The inflated vest compresses the patient's chest and increases the intrathoracic pressure. This increase in pressure assists the heart in moving blood out of the heart and through the aorta. In addition, the vest is arranged to leave the patient's abdomen free of restraint so that the increase in intrathoracic pressure due to the vest moves blood into the abdomen, and to allow the abdomen to dynamically recoil in response to the vest inflation. In addition, ECG signals from electrodes applied to the patient are processed to trigger the vest inflation in real time with the current heartbeat cycle, such that the vest inflation is triggered when the heart begins to contract.Type: GrantFiled: January 29, 2001Date of Patent: June 22, 2004Assignee: Revivant CorporationInventors: Neil S. Rothman, Mark Gelfand, Daniel Burkhoff, Myron L. Weisfeldt
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Publication number: 20030216679Abstract: Disclosed is a conduit that provides a bypass around a stenosis or occlusion in a coronary artery. The conduit is adapted to be positioned in the myocardium to provide a passage for blood to flow from a heart chamber to a coronary artery, at a site distal to the blockage or stenosis in the coronary artery. The conduit has a one-way valve positioned therein to prevent the backflow of blood from the coronary artery into the heart chamber.Type: ApplicationFiled: June 18, 2003Publication date: November 20, 2003Applicant: Percardia, Inc.Inventors: Scott J. Wolf, Greg R. Furnish, Todd A. Hall, David Y. Phelps, Peter J. Wilk, Nancy M. Briefs, William Santamore, Daniel Burkhoff
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Publication number: 20030216678Abstract: A method for inducing vascular remodeling and related methods for treating patients having diseased vasculature. The method of inducing remodeling of the vascular system includes altering the blood flow dynamics in portions of the vascular system via mechanical mechanisms. Remodeling of certain coronary vasculature may be induced by creating a passage in a heart wall between a heart chamber and a blood vessel so as to permit blood flow communication, for example, direct blood flow communication, between the chamber and the vessel. A method of inducing vascular remodeling may include providing a blood flow passage between a heart chamber and the coronary vessel, or other flow dynamics altering structure, such that enlargement of at least a portion of the coronary vessel occurs.Type: ApplicationFiled: March 17, 2003Publication date: November 20, 2003Inventors: Keith March, Richard Popp, Peter Fitzgerald, Patrick Cahalan, Daniel Burkhoff, Laurence Roth, Nancy Briefs, William Santamore, Robert Swain, Peter Boekstegers, Vincent Pompili
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Patent number: 6641610Abstract: Disclosed is a conduit that provides a bypass around a stenosis or occlusion in a coronary artery. The conduit is adapted to be positioned in the myocardium to provide a passage for blood to flow from a heart chamber to a coronary artery, at a site distal to the blockage or stenosis in the coronary artery. The conduit has a one-way valve positioned therein to prevent the backflow of blood from the coronary artery into the heart chamber.Type: GrantFiled: August 4, 1999Date of Patent: November 4, 2003Assignee: Percardia, Inc.Inventors: Scott J. Wolf, Greg R. Furnish, Todd A. Hall, David Y. Phelps, Peter J. Wilk, Nancy C. Briefs, William Santamore, Daniel Burkhoff
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Publication number: 20030113304Abstract: The effects of angiogenesis created by tissue injury resulting from ischemic tissue being revascularized by transmyocardial revascularization are amplified by introducing cells containing an angiogenic agent into a patient positive to antigenic determinant such as Fik-1, Tie-2 or CD-34. Cells such as CD 34+ cells migrate to a site of angiogenesis and will thus efficiently carry the angiogenic agent to the site without requiring local introduction. Thus, a section of ischemic myocardium can be revascularized by performing TMR to create a number of sites of injury, and then introducing hematopoietic stem cells, for example CD 34+ cells, that contain a growth factor, genetic material or other angiogenic agent into the patient, most preferably by systemic introduction. As a result, the increase in vascularization will be greater than that exhibited by TMR alone or by the insertion of an angiogenic agent alone.Type: ApplicationFiled: November 19, 2002Publication date: June 19, 2003Applicant: The Trustees of Columbia UniversityInventor: Daniel Burkhoff
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Publication number: 20030055371Abstract: Left ventricular conduits and related methods are disclosed for achieving bypass of a partially or completely occluded coronary artery. More broadly, conduits for allowing communication of bodily fluids from one portion of a patient's body to another and related methods are disclosed, including conduits for forming a blood flow path from a chamber of the heart to a vessel or from one vessel to another. In other embodiments, the conduits achieve a coronary artery bypass by allowing blood communication between the left ventricle and the coronary artery or between a proximal portion of the coronary artery and a distal portion of the coronary artery. The conduits may be placed completely through the heart wall or extend only partially therein. Conduits may take on a variety of configurations for allowing the control of blood flow therethrough, including curved or tapered shapes.Type: ApplicationFiled: August 15, 2002Publication date: March 20, 2003Applicant: Percardia, Inc.Inventors: Scott J. Wolf, Greg R. Furnish, Todd A. Hall, David Y. Phelps, Peter J. Wilk, Nancy C. Briefs, William Santamore, Daniel Burkhoff, Simon Furnish, Stephen Evans, Roger D. Kamm, Richard Renati, Gerald Melsky, Eun Bo Shim
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Publication number: 20020165606Abstract: Disclosed is a conduit that provides a bypass around a stenosis or occlusion in a coronary artery. The conduit is adapted to be positioned in the myocardium to provide a passage for blood to flow from a heart chamber to a coronary artery, at a site distal to the blockage or stenosis in the coronary artery. The conduit has a one-way valve positioned therein to prevent the backflow of blood from the coronary artery into the heart chamber.Type: ApplicationFiled: August 4, 1999Publication date: November 7, 2002Inventors: SCOTT J. WOLF, GREG R. FURNISH, TODD A. HALL, DAVID Y. PHELPS, PETER J. WILK, NANCY C. BRIEFS, WILLIAM SANTAMORE, DANIEL BURKHOFF
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Publication number: 20010027279Abstract: A method and device are disclosed for inflating an inflatable vest to assist the heart in patients suffering from heart failure. The inflation of the vest is synchronized with on-set of the systole phase of the heart, when the left ventricular compresses to force blood out of the heart and through the aorta. The inflated vest compresses the patient's chest and increases the intrathoracic pressure. This increase in pressure assists the heart in moving blood out of the heart and through the aorta. In addition, the vest is arranged to leave the patient's abdomen free of restraint so that the increase in intrathoracic pressure due to the vest moves blood into the abdomen, and to allow the abdomen to dynamically recoil in response to the vest inflation. In addition, ECG signals from electrodes applied to the patient are processed to trigger the vest inflation in real time with the current heartbeat cycle, such that the vest inflation is triggered when the heart begins to contract.Type: ApplicationFiled: January 29, 2001Publication date: October 4, 2001Inventors: Neil S. Rothman, Mark Gelfand, Daniel Burkhoff, Myron L. Weisfeldt
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Patent number: 6267757Abstract: The invention is directed to an intracorporeal device for myocardial revascularization of a patient's heart tissue by at least one burst of RF energy over an interval of about 1 to about 500 msec, preferably about 30 to about 130 msec. The intracorporeal device has an elongated insulated, electrical conducting shaft with an uninsulated distal tip which is configured to emit RF energy. The uninsulated distal tip has a diameter of about 0.025 to about 0.2 inch, preferably about 0.04 to about 0.08 inch and a length of about 0.1 to about 5 mm, preferably about 1.5 to about 3.5 mm.Type: GrantFiled: October 2, 1997Date of Patent: July 31, 2001Assignee: Eclipse Surgical Technologies, Inc.Inventors: Michael Aita, Daniel Burkhoff, Noriyoshi Yamamoto, Miriam H. Taimisto, Kenneth P. Aron, Christopher J. Danek
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Patent number: 6246898Abstract: A method for carrying out a medical procedure using a 3-D tracking and imaging system (1600). A surgical instrument, such as a catheter, probe, sensor, pacemaker lead, needle, or the like is inserted into a living being, and the position of the surgical instrument is tracked as it moves through a medium in a bodily structure. The location of the surgical instrument relative to its immediate surroundings is displayed to improve a physician's ability to precisely position the surgical instrument. The medical procedures including targeted drug delivery, sewing sutures, removal of an obstruction from the circulatory system, a biopsy, amniocentesis, brain surgery, measurement of cervical dilation, evaluation of knee stability, assessment of myocardial contractibility, eye surgery, prostate surgery, trans-myocardial revascularization (TMR), robotic surgery, and evaluation of RF transmissions.Type: GrantFiled: May 8, 1998Date of Patent: June 12, 2001Assignee: Sonometrics CorporationInventors: Ivan Vesely, Wayne Smith, George Klein, Daniel Burkhoff
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Patent number: 6179793Abstract: A method is disclosed for inflating an inflatable vest to assist the heart in patients suffering from heart failure. The inflation of the vest is synchronized with on-set of the systole phase of the heart, when the left ventricular compresses to force blood out of the heart and through the aorta. The inflated vest compresses the patient's chest and increases the intrathoracic pressure. This increase in pressure assists the heart in moving blood out of the heart and through the aorta. In addition, the vest is arranged to leave the patient's abdomen free of restraint so that the increase in intrathoracic pressure due to the vest moves blood into the abdomen, and to allow the abdomen to dynamically recoil in response to the vest inflation. In addition, ECG signals from electrodes applied to the patient are processed to trigger the vest inflation in real time with the current heartbeat cycle, such that the vest inflation is triggered when the heart begins to contract.Type: GrantFiled: January 14, 1998Date of Patent: January 30, 2001Assignee: Revivant CorporationInventors: Neil S. Rothman, Mark Gelfand, Daniel Burkhoff, Myron L. Weisfeldt
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Patent number: 6076013Abstract: Apparatus and method for the treatment of congestive heart failure are disclosed that utilize a cuff that surrounds the heart and constrains cardiac dilation, while electrodes embedded in the cuff stimulate the myocardium to contractile function. An EKG signal can be processed to create an optimal pattern of selective stimulation of different areas of the heart at different times. An implantable circuit contains a power source and stimulation circuits. In some embodiments, a telemetry unit and an EKG collection circuit are also included. In accordance with the present disclosure, cuff limits the dilation of the heart and the stimulation electrodes enhance ventricular function by optimizing ventricular contractility.Type: GrantFiled: January 14, 1999Date of Patent: June 13, 2000Inventors: Edward F. Brennan, Daniel Burkhoff