Patents by Inventor Daniel C. Bertrand

Daniel C. Bertrand has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cholinergic/serotoninergic receptor and uses thereof
    Patent number: 8759504
    Abstract: The present invention describes new cholinergic/serotoninergic chimeric receptors and provides methods and compositions suitable for screening for ligands such as agonists, antagonists and allosteric modulators of ?7 nicotinic acetylcholine receptors.
    Type: Grant
    Filed: February 6, 2012
    Date of Patent: June 24, 2014
    Assignee: AbbVie Inc.
    Inventors: Murali Gopalakrishnan, Jinhe Li, Steven C. Cassar, John Malysz, David J. Anderson, Earl J. Gubbins, Daniel C. Bertrand
  • CHOLINERGIC/SEROTONINERGIC RECEPTOR AND USES THEREOF
    Publication number: 20120219967
    Abstract: The present invention describes new cholinergic/serotoninergic chimeric receptors and provides methods and compositions suitable for screening for ligands such as agonists, antagonists and allosteric modulators of ?7 nicotinic acetylcholine receptors.
    Type: Application
    Filed: February 6, 2012
    Publication date: August 30, 2012
    Inventors: Murali Gopalakrishnan, Jinhe Li, Steven C. Cassar, John Malysz, David J. Anderson, Earl J. Gubbins, Daniel C. Bertrand
  • CHOLINERGIC/SEROTONINERGIC RECEPTOR AND USES THEREOF
    Publication number: 20090123945
    Abstract: The present invention describes new cholinergic/serotoninergic chimeric receptors and provides methods and compositions suitable for screening for ligands such as agonists, antagonists and allosteric modulators of ?7 nicotinic acetylcholine receptors.
    Type: Application
    Filed: June 25, 2008
    Publication date: May 14, 2009
    Applicant: ABBOTT LABORATORIES
    Inventors: Murali Gopalakrishnan, Jinhe Li, Steven C. Cassar, John Malysz, David J. Anderson, Earl J. Gubbins, Daniel C. Bertrand
  • Apparatus and method for electrophysiological testing
    Patent number: 7011939
    Abstract: A method and apparatus for running a plurality of tests concurrently to obtain data relating to the electrophysiological properties of receptors and channels in biological membranes of test subjects, such as, for example, Xenopus oocytes. The invention further provides software for controlling, acquiring, and recording data relating to electrophysiological properties of receptors and channels in biological membranes of test subjects, such as, for example, oocytes. This invention increases the throughput rate for experiments and assays employing receptors and ion channels expressed in biological membranes of test subjects, such as, for example, oocytes. In the case of an oocyte, these receptors and channels may be natively expressed (endogenous), may be placed into the oocyte (exogenous), or may be expressed from other RNA or DNA previously placed into the oocyte (exogenous).
    Type: Grant
    Filed: February 23, 2001
    Date of Patent: March 14, 2006
    Assignee: Abbott Laboratories
    Inventors: Jonathan D. Trumbull, Daniel C. Bertrand, Clark A. Briggs, David G. McKenna, Eugene S. Maslana, David P. Blanchard, Jeffrey Y. Pan, Peter Bojan, Thomas A. Nemcek
  • Apparatus and method for electophysiological testing
    Publication number: 20010029320
    Abstract: A method and apparatus for running a plurality of tests concurrently to obtain data relating to the electrophysiological properties of receptors and channels in biological membranes of test subjects, such as, for example, Xenopus oocytes. The invention further provides software for controlling, acquiring, and recording data relating to electrophysiological properties of receptors and channels in biological membranes of test subjects, such as, for example, oocytes. This invention increases the throughput rate for experiments and assays employing receptors and ion channels expressed in biological membranes of test subjects, such as, for example, oocytes. In the case of an oocyte, these receptors and channels may be natively expressed (endogenous), may be placed into the oocyte (exogenous), or may be expressed from other RNA or DNA previously placed into the oocyte (exogenous).
    Type: Application
    Filed: February 23, 2001
    Publication date: October 11, 2001
    Inventors: Jonathan D. Trumbull, Daniel C. Bertrand, Clark A. Briggs, David G. McKenna, Eugene S. Maslana, David P. Blanchard, Jeffrey Y. Pan, Peter Bojan, Thomas A. Nemcek