Abstract: The present application provides, in some aspects, methods of identifying a condensate of interest associated with a el disease. Also provided are methods of identifying a marker for identifying a condensate of interest associated with a disease. In other aspects, provided herein are methods of identifying a therapeutic agent useful for treating a disease via the identified condensate of interest.

Abstract: Described herein are methods and computer systems for classification of CD8 T-cell topology using a patient response-based linear cutoff model. A plurality of histology images of tissue samples in a plurality of patients are received by a computer system. An image analysis of the plurality of histology images is performed to obtain a CD8+ T-cell abundance in the tumor parenchyma and stroma in each of the plurality of histology images. Real inflammation scores and tumor infiltration scores are determined based on a polar coordinate transformation of the CD8+ T-cell abundance in the tumor parenchyma and stroma. Based on the real inflammation scores and tumor infiltration scores, a feature space is generated, and linear boundaries or linear cutoffs between a plurality of classifications in the feature space are identified based on the real inflammation scores, the tumor infiltration scores, and patient response data.

Abstract: A system and method for controlling use of content in accordance with usage rights associated with the content and determined in accordance with the environment of a user device. A request is received for secure content from a user device and the integrity of the environment of the user device is verified. Appropriate usage rights are retrieved based upon the results of the verification of integrity and the content is rendered on the user device in accordance with the appropriate usage rights.

Abstract: A system and method for controlling use of content in accordance with usage rights associated with the content and determined in accordance with the environment of a user device. A request is received for secure content from a user device and the integrity of the environment of the user device is verified. Appropriate usage rights are retrieved based upon the results of the verification of integrity and the content is rendered on the user device in accordance with the appropriate usage rights.

Abstract: The publishing system and method automates at least some portion of a publishing process. The system publishes content using metadata, rights templates and/or specifications, publishing profiles and business rules.

Abstract: The publishing system and method automates at least some portion of a publishing process. The system publishes content using metadata, rights templates and/or specifications, publishing profiles and business rules.

Abstract: The publishing system and method automates at least some portion of a publishing process. The system publishes content using metadata, rights templates and/or specifications, publishing profiles and business rules.

Abstract: The publishing system and method automates at least some portion of a publishing process. The system publishes content using metadata, rights templates and/or specifications, publishing profiles and business rules.

Abstract: A system and method for controlling use of content in accordance with usage rights associated with the content and determined in accordance with the environment of a user device. A request is received for secure content from a user device and the integrity of the environment of the user device is verified. Appropriate usage rights are retrieved based upon the results of the verification of integrity and the content is rendered on the user device in accordance with the appropriate usage rights.

Abstract: The publishing system and method automates at least some portion of a publishing process. The system publishes content using metadata, rights templates and/or specifications, publishing profiles and business rules.

Abstract: A system and method for controlling use of content in accordance with usage rights associated with the content and determined in accordance with the environment of a user device. A request is received for secure content from a user device and the integrity of the environment of the user device is verified. Appropriate usage rights are retrieved based upon the results of the verification of integrity and the content is rendered on the user device in accordance with the appropriate usage rights.

Abstract: The publishing system and method automates at least some portion of a publishing process. The system publishes content using metadata, rights templates and/or specifications, publishing profiles and business rules.

Abstract: A method and apparatus provide for recovering from faults in an electronic reprographic system for scanning and synchronously or asynchronously processing and printing a plurality of jobs. The system is monitored for the occurrence of faults in a job, the faults are identified and recorded through a fault logging service and a specific response is initiated to the faults recorded by the fault logging service. Provision is made for using the log offline to determine the cause and effect of problems created by the faults in the system. The invention further provides for using the log online to monitor the occurrence of hardware faults in the system, and initiate the appropriate online diagnostic routine, whose response can further isolate a suspected problem.

Abstract: A method for testing and comparing the access times of disk drives in a real time system containing a multiplicity of likes drives. The method includes the steps of generating random locations for each of the drives to access, initializing each of the drives to a common position, determining the time period for each of the drives to find and read the random locations, comparing the differences in the time periods to a threshold value, and declaring a fault upon detecting any of the differences exceeding the said threshold.

Abstract: A transistor (42) is provided having a gate conductor (44) formed adjacent a semiconductor substrate (46) and separated therefrom by a gate insulator (48). Sidewall spacers (52, 54) are formed at the sides of gate conductor (44) and adjacent semiconductor substrate (46). Diffused regions (56, 58) are formed within semiconductor substrate (46) in order to provide source/drain regions for transistor (42). Positive charges from radiation are trapped within sidewall spacers (52, 54) thereby attracting negative charges from semiconductor substrate (46) such that a negative charge layer is created between diffused region (56) and gate edge (50a) and also between diffused region (58) and gate edge (50b).