Patents by Inventor Daniel C. ELLWANGER

Daniel C. ELLWANGER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TREM2 AGONIST BIOMARKERS AND METHODS OF USE THEREOF
    Publication number: 20240102094
    Abstract: The present invention provides a method of treating a disease or conditions associated with a dysfunction of TREM2 in a human patient, such as Alzheimer's disease, comprising administering to the patient a TREM2 agonist. In another aspect, the invention provides a method of assaying a biological sample taken from a patient having Alzheimer's for biomarkers to determine potential benefit or if the disease has an increased probability of responding to treatment with a TREM2 agonist.
    Type: Application
    Filed: December 3, 2021
    Publication date: March 28, 2024
    Applicant: AMGEN INC.
    Inventors: Daniel C. ELLWANGER, Ian N. FOLTZ, Samuel A. HASSON