Abstract: Disubstituted octahydropyrrolo[3,4-c]pyrrole compounds are described, which are useful as orexin receptor modulators. Such compounds may be useful in pharmaceutical compositions and methods for the treatment of diseased states, disorders, and conditions mediated by orexin activity, such as insomnia.

Abstract: A handheld computer device is configured to selectively receive a plurality of fluid output values from a paint sprayer and configured to operate in an accessible mode in which the handheld computer device is in a first location where wireless connectivity, via a continuous or near continuous communication path, to at least one of a network server or the paint sprayer is accessible or operate in an inaccessible mode in which the handheld computer device is in a second location out of range of the continuous or near continuous communication path to at least one of the network server or the paint sprayer.

Abstract: A handheld computer device is configured to selectively receive a plurality of fluid output values from a paint sprayer and configured to operate in an accessible mode in which the handheld computer device is in a first location where wireless connectivity, via a continuous or near continuous communication path, to at least one of a network server or the paint sprayer is accessible or operate in an inaccessible mode in which the handheld computer device is in a second location out of range of the continuous or near continuous communication path to at least one of the network server or the paint sprayer.

Abstract: A handheld computer device is configured to selectively receive a plurality of fluid output values from a paint sprayer and configured to operate in an accessible mode in which the handheld computer device is in a first location where wireless connectivity, via a continuous or near continuous communication path, to at least one of a network server or the paint sprayer is accessible or operate in an inaccessible mode in which the handheld computer device is in a second location out of range of the continuous or near continuous communication path to at least one of the network server or the paint sprayer.

Abstract: Various methods and devices are provided for allowing multiple surgical instruments to be inserted into sealing elements of a single surgical access device. The sealing elements can be movable along predefined pathways within the device to allow surgical instruments inserted through the sealing elements to be moved laterally, rotationally, angularly, and vertically relative to a central longitudinal axis of the device for ease of manipulation within a patient's body while maintaining insufflation.

Abstract: A trap has a housing including an entrance. Internally, the trap has a trigger structure including a trigger plate and a latch mechanism, coupled with the housing; and a pivoting structure pivotally coupled with the housing and adapted to releasably engage with the latch mechanism of the trigger structure. When the trap is triggered by a rodent, the pivoting structure disengages from the latch mechanism and the pivoting structure pivots towards a rear wall of the housing and the trigger plate, and the trigger plate pivots toward the pivoting structure, moving the rodent against towards the rear wall of the housing and trapping the rodent between the pivoting structure and the rear wall. Once the trap is triggered, the rodent is contained and in most cases, killed, within the trap.

Abstract: A bi-directional steerable catheter may include a handle and an elongate sheath extending distally from the handle. The handle includes an axial translation mechanism. A first steering wire extends through the elongate sheath from the handle to a distal pull ring. A second steering wire extends through the elongate sheath from the handle to the distal pull ring, the second steering wire being disposed on an opposite side of the elongate sheath from the first steering wire relative to a central longitudinal axis. The first steering wire is configured to engage with the axial translation mechanism to bend a distal portion of the elongate sheath in a first direction. The second steering wire is configured to engage with the axial translation mechanism to bend the distal portion in a second direction opposite the first direction. A tensioning member couples a proximal end of the first steering wire to the handle.

Abstract: A rodent trap includes a base, a strike member, a biasing member, and a trigger. The base defines a base interior and an opening. The strike member is movably coupled to the base for linear travel between an extended position and a retracted position. The strike member comprises a tunnel element extending through the opening of the base. The strike member defines an entryway that communicates with the base interior. The biasing member is coupled to the base and the strike member. The biasing member is configured to bias the strike member toward the retracted position. The trigger is movably coupled to the base. The trigger is configured to contact an outer surface of the strike member in the extended position. When the trigger dislodges from the outer surface of the strike member, the strike member linearly travels to the retracted position.

Abstract: A trap has a housing including an entrance. Internally, the trap has a trigger structure including a trigger plate and a latch mechanism, coupled with the housing; and a pivoting structure pivotally coupled with the housing and adapted to releasably engage with the latch mechanism of the trigger structure. When the trap is triggered by a rodent, the pivoting structure disengages from the latch mechanism and the pivoting structure pivots towards a rear wall of the housing and the trigger plate, and the trigger plate pivots toward the pivoting structure, moving the rodent against towards the rear wall of the housing and trapping the rodent between the pivoting structure and the rear wall. Once the trap is triggered, the rodent is contained and in most cases, killed, within the trap.

Abstract: A rodent trap covered base defines an enclosed interior accessible through a sliding plastic tunnel defining a passageway for rodents into the interior. The tunnel has a projecting strike member, and is biased by an underlying spring to a retracted position. A trigger engaging member extends from the tunnel to be retained by a catch on a trigger mounted to the base. When a rodent passes through the tunnel into the base interior, it is directed by barriers towards a rodent attracting bait. To reach the bait, the rodent must press against a pivotably mounted trigger, thereby dislodging the trigger from the trigger engaging member which releases the tunnel to be driven by the spring to retract along parallel tracks to bring the strike plate forcibly against the rodent within the trap, usually killing it, and closing the trap, which is then presented covered within the trap for disposal.

Abstract: A tray for a bait station, the tray for holding rodent bait or a rodent trap, where the rodent bait station has a base with a hinged cover which is lockable to the base to define an interior volume which can receive a ballast weight of three to twenty-four pounds which biases a floor of the base against a support surface. The station has at least two rodent access openings and upward leading ramps, the ramps leading to and being overlain by a landing which forms a portion of the tray and which allows a rodent to pass onto a tray proper which contains the bait or trap. The opening, ramps, and landing are such that a rodent can move freely within the interior volume so as to access the bait or rodent trap on the tray.

Abstract: A pre-baited consumer bait station for rodents which is gnaw resistant and has other design features to make the bait station resistant to rodenticide access by children, dogs, other pets, domestic animals, and nontarget wildlife. An injection molded translucent cover is permanently locked to a base about the cover's edges and center by elastic actuated hooks which engage receptacles on the base. The cover forms a labyrinth joint with a peripheral wall of the base. Double walls on exterior portions of the peripheral wall strengthen the walls where they form part of a closely confining bait receptacle which surrounds a bait block on portions of all sides. Circuitous internal passageways limit access to the bait. An interior wall extends to support the cover center.

Abstract: A rodent trap covered base defines an enclosed interior accessible through a sliding plastic tunnel defining a passageway for rodents into the interior. The tunnel has a projecting strike member, and is biased by an underlying spring to a retracted position. A trigger engaging member extends from the tunnel to be retained by a catch on a trigger mounted to the base. When a rodent passes through the tunnel into the base interior, it is directed by barriers towards a rodent attracting bait. To reach the bait, the rodent must press against a pivotably mounted trigger, thereby dislodging the trigger from the trigger engaging member which releases the tunnel to be driven by the spring to retract along parallel tracks to bring the strike plate forcibly against the rodent within the trap, usually killing it, and closing the trap, which is then presented covered within the trap for disposal.

Abstract: A rodent trap having a covered base defines an enclosed interior accessible through a sliding plastic tunnel defining a passageway for rodents into the interior. The tunnel has a projecting strike member, and is biased by an underlying spring to a retracted position. A trigger engaging member extends from the tunnel to be retained by a catch on a trigger mounted to the base. When a rodent passes through the tunnel into the base interior, it is directed by barriers towards a rodent attracting bait. To reach the bait, the rodent must press against a pivotably mounted trigger, thereby dislodging the trigger from the trigger engaging member which releases the tunnel to be driven by the spring to retract along parallel tracks to bring the strike plate forcibly against the rodent within the trap, usually killing it, and closing the trap.

Abstract: A trap has a housing including an entrance. Internally, the trap has a trigger structure including a trigger plate and a latch mechanism, coupled with the housing; and a pivoting structure pivotally coupled with the housing and adapted to releasably engage with the latch mechanism of the trigger structure. When the trap is triggered by a rodent, the pivoting structure disengages from the latch mechanism and the pivoting structure pivots towards a rear wall of the housing and the trigger plate, and the trigger plate pivots toward the pivoting structure, moving the rodent against towards the rear wall of the housing and trapping the rodent between the pivoting structure and the rear wall. Once the trap is triggered, the rodent is contained and in most cases, killed, within the trap.

Abstract: A rodent bait station has a base with a hinged cover which is lockable to the base to define an interior volume which can receive a ballast weight of three to twenty-four pounds which biases a floor of the base against a support surface. At least one rodent access opening in the bait station allows a rodent to pass into the interior volume. A bait or a rodent trap is positioned within the interior volume such that a rodent can move freely within the interior volume so as to access the bait or rodent trap.

Abstract: A rodent bait station for retention of sachet bait, which is a malleable bait retained within a porous bag or package having sidewardly protruding flaps. The bait station may be a molded plastic structure with a lid hinged to a base. Base walls define a bait compartment sized to receive the sachet bait such that the flaps overlie the opposed bait compartment base walls. The lid has downwardly protruding bait compartment walls which overlie the base bait compartment walls. Undulating or jagged teeth are formed on the lid and base bait compartment walls. When the lid is closed on the base, the teeth projecting from the lid cooperate with the teeth protruding from the base, thereby engaging and clamping a retained sachet bait package flaps to thus retain the package with the bait station even after a rodent has broken into the package to access the poison contained therein.