Abstract: Described herein are compounds that are inhibitors of autophagy and their use in the treatment of disorders such as cancers.

Abstract: Described herein are compounds that are inhibitors of wild type and oncogenic mutant c-KIT kinase and their use in the treatment of disorders such as cancers.

Abstract: The present invention provides a controller for hydraulic apparatus (100). The controller is configured to determine (310) that an energy return criteria has been met by movement of a first movement component of a first hydraulic actuator. In response thereto, the controller is further configured to select (320) at least one among a plurality of energy control strategies based on at least one operational characteristic of the hydraulic apparatus, and to control (330) the hydraulic apparatus to implement the energy control strategy during movement of the first movable component in such a way as to meet the energy return criteria. The plurality of energy control strategies comprises a first energy control strategy and a second energy control strategy. The at least one operational characteristic of the hydraulic apparatus comprises an indication of an expected energy recovery of one or more of the energy control strategies.

Abstract: Glass elements are provided that include a coating and a sheet-like glass substrate. The sheet-like glass substrate has a first surface and a second surface opposite the first surface. The coating is disposed in at least some areas of at least one of the first and second surfaces. The coating is an inorganic glass-based coating that includes at least one glassy component; at least one pigment comprising pigment particles; and a filler. The filler is inorganic and includes filler particles with a d50 value, based on an equivalent diameter, of at least 0.1 ?m and less than 10 ?m.

Abstract: A surgical device having a body with a proximal end and a distal end; a hollow cannula extending from the distal end of the body, the cannula having a proximal end and a distal end; an operative head positioned at the distal end of the cannula; and a suction connector in fluid communication with the hollow cannula, the suction connector being configured for connection to a suction source; wherein the hollow cannula has at least one of the group consisting of diverters and rifling on at least a portion of an inside surface.

Abstract: The present disclosure provides a coated glass substrate, first and second coating compositions, and a process for coating the substrate. The first composition includes a source of tin, a source of fluorine, a source of titanium, and a solvent. The second composition includes a source of tin, a source of fluorine, and a solvent, and can be free of titanium. The first composition is applied to the substrate under elevated temperatures, and a first or sub layer is formed on the substrate via pyrolysis. The second composition is then applied, to form a second or top layer over the sub layer.

Abstract: The present disclosure provides a coated glass substrate, first and second coating compositions, and a process for coating the substrate. The first composition includes a source of tin, a source of fluorine, a source of titanium, and a solvent. The second composition includes a source of tin, a source of fluorine, and a solvent, and can be free of titanium. The first composition is applied to the substrate under elevated temperatures, and a first or sub layer is formed on the substrate via pyrolysis. The second composition is then applied, to form a second or top layer over the sub layer.

Abstract: Glass elements are provided that include a coating and a sheet-like glass substrate. The sheet-like glass substrate has a first surface and a second surface opposite the first surface. The coating is disposed in at least some areas of at least one of the first and second surfaces. The coating is an inorganic glass-based coating that includes at least one glassy component; at least one pigment comprising pigment particles; and a filler. The filler is inorganic and includes filler particles with a d50 value, based on an equivalent diameter, of at least 0.1 ?m and less than 10 ?m.

Abstract: The present disclosure provides a coated glass substrate, first and second coating compositions, and a process for coating the substrate. The first composition includes a source of tin, a source of fluorine, a source of titanium, and a solvent. The second composition includes a source of tin, a source of fluorine, and a solvent, and can be free of titanium. The first composition is applied to the substrate under elevated temperatures, and a first or sub layer is formed on the substrate via pyrolysis. The second composition is then applied, to form a second or top layer over the sub layer.

Abstract: The present disclosure provides a coated glass substrate, first and second coating compositions, and a process for coating the substrate. The first composition includes a source of tin, a source of fluorine, a source of titanium, and a solvent. The second composition includes a source of tin, a source of fluorine, and a solvent, and can be free of titanium. The first composition is applied to the substrate under elevated temperatures, and a first or sub layer is formed on the substrate via pyrolysis. The second composition is then applied, to form a second or top layer over the sub layer.

Abstract: The present invention provides a method for planarizing/polishing a surface, a method for manufacturing an integrated circuit and a chemical mechanical polishing apparatus. The method for planarizing/polishing a surface, among other elements, includes providing a chemical mechanical polishing apparatus (200, 300, 400) having a polishing platen (210, 310, 410), a carrier head (220, 320, 420) positioned over the polishing platen (210, 310, 410), and a slurry delivery source (230, 330, 430) positioned over and off center the polishing platen (210, 310, 410), and rotating the polishing platen (210, 310, 410) in a direction (Rp2, Rp3, Rp4) such that slurry exiting the slurry delivery source (230, 330, 430) and contacting the polishing platen (210, 310, 410) must rotate an angle (?2, ?3, ?4) less than about 220 degrees before contacting a polishable surface maintained by the carrier head (220, 320, 420).

Abstract: This invention is directed to a system and method for creating characterization information and a correction map from a first display grid that can be transmitted and used by a second display grid. Computer readable instructions embodied in a computer readable medium calibrate a first display grid and create an ICC color profile and correction map from said calibration information, such that an image to be displayed across an entire display grid which is segmented into portions corresponding to each display device in the display grid is displayed with uniform luminance and color across the entire display grid. The invention can then store the correction map and characterization information and send the information to a second display device for it to use. Alternatively, the calibration or characterization information can be associated with an image file and sent to a second location for display.

Abstract: According to one embodiment of the invention, a chemical mechanical polishing monitoring system includes a pump delivering a slurry to a polishing pad and a rotation sensing device coupled to the pump. The rotation sensing device senses a rotation of the pump and generates a signal indicative of the rotation of the pump.