Patents by Inventor Daniel Campton

Daniel Campton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180364136
    Abstract: This disclosure is directed to a method and an attachment solution for adhering a cytological or histological sample, such as buffy coat, to a substrate, such as a microscope slide. The attachment solution includes an attachment base, an anti-coagulant, and a nonsteroidal anti-inflammatory drug. The attachment base may be an alcohol, an acid, an oxidizer, an organohalogen, a ketone, or any combination thereof. Once a sample is obtained, the sample may be re-suspended in the attachment solution or the attachment solution may be added to the sample. The sample may then be dispensed onto an analysis platform as one or more droplets and cured.
    Type: Application
    Filed: August 27, 2018
    Publication date: December 20, 2018
    Inventors: Daniel CAMPTON, Joshua NORDBERG, Ronald SEUBERT
  • Patent number: 10101248
    Abstract: This disclosure is directed to a method and an attachment solution for adhering a cytological or histological sample, such as buffy coat, to a substrate, such as a microscope slide. The attachment solution includes an attachment base, an anti-coagulant, and a nonsteroidal anti-inflammatory drug. The attachment base may be an alcohol, an acid, an oxidizer, an organohalogen, a ketone, or any combination thereof. Once a sample is obtained, the sample may be re-suspended in the attachment solution or the attachment solution may be added to the sample. The sample may then be dispensed onto an analysis platform as one or more droplets and cured.
    Type: Grant
    Filed: October 18, 2017
    Date of Patent: October 16, 2018
    Assignee: RareCyte, Inc.
    Inventors: Daniel Campton, Joshua Nordberg, Ronald Seubert
  • Patent number: 10101247
    Abstract: This disclosure is directed to a method and an attachment solution for adhering a cytological or histological sample, such as buffy coat, to a substrate, such as a microscope slide. The attachment solution includes an attachment base, an anti-coagulant, and a nonsteroidal anti-inflammatory drug. The attachment base may be an alcohol, an acid, an oxidizer, an organohalogen, a ketone, or any combination thereof. Once a sample is obtained, the sample may be re-suspended in the attachment solution or the attachment solution may be added to the sample. The sample may then be dispensed onto an analysis platform as one or more droplets and cured.
    Type: Grant
    Filed: December 2, 2015
    Date of Patent: October 16, 2018
    Assignee: RareCyte, Inc.
    Inventors: Daniel Campton, Joshua Nordberg, Ronald Seubert, Steve Quarre
  • Publication number: 20180238778
    Abstract: This disclosure is directed to an apparatus and method for spreading a fluid across a substrate. A spreader for spreading a fluid across a substrate includes a wiper and a frame. The wiper and the frame may mate to permit translation of the wiper across, and with respect to, the frame. The wiper spreads the fluid across the substrate and the frame supports the wiper and the substrate. The frame may also include a ramp to cause a portion of the wiper to lift away from the substrate.
    Type: Application
    Filed: April 25, 2018
    Publication date: August 23, 2018
    Inventors: Joshua NORDBERG, Daniel CAMPTON, Steve QUARRE, David STEWART
  • Patent number: 10054524
    Abstract: This disclosure is directed to an apparatus, system and method for retrieving a target material from a sample. An enrichment agent may be added to a vessel that contains the sample for positive selection, or, in other words, to select or aid in selecting the target material from amongst the remainder of the sample. The enrichment agent may be, for example, immunomagnetic beads, buoyant beads, high-density beads, chemicals to change the density of the target material, or the like.
    Type: Grant
    Filed: November 2, 2016
    Date of Patent: August 21, 2018
    Assignee: RareCyte, Inc.
    Inventors: Daniel Campton, Joshua Nordberg, Steve Quarre, David Stewart, Ronald Seubert, Jonathan Lundt, Lance U'Ren, Jennifer Chow
  • Patent number: 10018538
    Abstract: This disclosure is directed to an apparatus and method for spreading a fluid across a substrate. A spreader for spreading a fluid across a substrate includes a wiper and a frame. The wiper and the frame may mate to permit translation of the wiper across, and with respect to, the frame. The wiper spreads the fluid across the substrate and the frame supports the wiper and the substrate. The frame may also include a ramp to cause a portion of the wiper to lift away from the substrate.
    Type: Grant
    Filed: November 22, 2015
    Date of Patent: July 10, 2018
    Assignee: RareCyte, Inc.
    Inventors: Joshua Nordberg, Daniel Campton, Steve Quarre, David Stewart
  • Patent number: 9945839
    Abstract: This disclosure is directed to an apparatus, system and method for retrieving a target material from a suspension. A system includes a displacement fluid, a collector, and a primary vessel. In another implementation, the system includes a processing vessel, a displacement fluid, a collector, and a primary vessel.
    Type: Grant
    Filed: November 14, 2016
    Date of Patent: April 17, 2018
    Assignee: RareCyte, Inc.
    Inventors: Daniel Campton, Joshua Nordberg, Steve Quarre, David Stewart, Ronald Seubert
  • Publication number: 20170322125
    Abstract: This disclosure is directed to solutions and methods of using the solutions. A first solution includes a polymer, a polyol, and a buffer. A second solution includes a polymer, a polyol, and an alcohol.
    Type: Application
    Filed: April 20, 2017
    Publication date: November 9, 2017
    Applicant: RareCyte, Inc.
    Inventor: Daniel Campton
  • Publication number: 20170191911
    Abstract: This disclosure is directed to an apparatus, system and method for retrieving a target material from a suspension. A system includes a plurality of processing vessels and a collector. The collector funnels portions of the target material from the suspension through a cannula and into the processing vessels. Sequential density fractionation is the division of a sample into fractions or of a fraction of a sample into sub-fractions by a step-wise or sequential process, such that each step or sequence results in the collection or separation of a different fraction or sub-fraction from the preceding and successive steps or sequences. In other words, sequential density fractionation provides individual sub-populations of a population or individual sub-sub-populations of a sub-population of a population through a series of steps.
    Type: Application
    Filed: January 8, 2017
    Publication date: July 6, 2017
    Applicant: RareCyte, Inc.
    Inventors: Daniel Campton, Joshua Nordberg, Steve Quarre, Ronald Seubert, Jonathan Lundt, Lance U'Ren
  • Publication number: 20170074759
    Abstract: This disclosure is directed to an apparatus, system and method for retrieving a target material from a sample. An enrichment agent may be added to a vessel that contains the sample for positive selection, or, in other words, to select or aid in selecting the target material from amongst the remainder of the sample. The enrichment agent may be, for example, immunomagnetic beads, buoyant beads, high-density beads, chemicals to change the density of the target material, or the like.
    Type: Application
    Filed: November 2, 2016
    Publication date: March 16, 2017
    Applicant: RareCyte, Inc.
    Inventors: Daniel Campton, Joshua Nordberg, Steve Quarre, David Stewart, Ronald Seubert, Jonathan Lundt, Lance U'Ren, Jennifer Chow
  • Publication number: 20170059552
    Abstract: This disclosure is directed to an apparatus, system and method for retrieving a target material from a suspension. A system includes a displacement fluid, a collector, and a primary vessel. In another implementation, the system includes a processing vessel, a displacement fluid, a collector, and a primary vessel.
    Type: Application
    Filed: November 14, 2016
    Publication date: March 2, 2017
    Applicant: RareCyte, Inc.
    Inventors: Daniel Campton, Joshua Nordberg, Steve Quarre, David Stewart, Ronald Seubert
  • Patent number: 9541481
    Abstract: This disclosure is directed to an apparatus, system and method for retrieving a target material from a sample. A first depletion agent may be added to a vessel that contains the sample to change the density of a non-target material.
    Type: Grant
    Filed: June 5, 2016
    Date of Patent: January 10, 2017
    Assignee: RareCyte, Inc.
    Inventors: Daniel Campton, Joshua Nordberg, Steve Quarre, David Stewart, Ronald Seubert, Jonathan Lundt, Lance U'Ren, Jennifer Chow
  • Patent number: 9539570
    Abstract: This disclosure is directed to an apparatus, system and method for retrieving a target material from a suspension. A system includes a plurality of processing vessels and a collector. The collector funnels portions of the target material from the suspension through a cannula and into the processing vessels. Sequential density fractionation is the division of a sample into fractions or of a fraction of a sample into sub-fractions by a step-wise or sequential process, such that each step or sequence results in the collection or separation of a different fraction or sub-fraction from the preceding and successive steps or sequences. In other words, sequential density fractionation provides individual sub-populations of a population or individual sub-sub-populations of a sub-population of a population through a series of steps.
    Type: Grant
    Filed: January 30, 2015
    Date of Patent: January 10, 2017
    Assignee: RareCyte, Inc.
    Inventors: Lance U'Ren, Daniel Campton, Joshua Nordberg, Steve Quarre, Jonathan Lundt
  • Patent number: 9533303
    Abstract: This disclosure is directed to an apparatus, system and method for retrieving a target material from a suspension. A system includes a primary vessel, such as a tube, a collector, and a two-part seal including an internal pliant part and an external constricting part. The internal pliant part may be a float and the external constricting part may be a sealing ring. The system may also include a processing vessel, such as an Eppendorf tube, a syringe or a test tube. The collector is sized and shaped to fit into a primary vessel and funnels the target material from the suspension through a cannula and into the processing vessel. In one implementation, the processing vessel includes at least one displacement fluid to be expelled, such that the at least one displacement fluid pushes the target material into the collector.
    Type: Grant
    Filed: May 7, 2015
    Date of Patent: January 3, 2017
    Assignee: RareCyte, Inc.
    Inventors: Daniel Campton, Joshua Nordberg, Steve Quarre, David Stewart, Ronald Seubert, Jonathan Lundt, Lance U'Ren
  • Patent number: 9513291
    Abstract: This disclosure is directed to an apparatus, system and method for retrieving a target material from a sample. A density-altering agent may be added to a vessel that contains the sample to change the density of a non-target material.
    Type: Grant
    Filed: February 9, 2016
    Date of Patent: December 6, 2016
    Assignee: RareCyte, Inc.
    Inventors: Daniel Campton, Joshua Nordberg, Steve Quarre, David Stewart, Ronald Seubert, Jonathan Lundt, Lance U'Ren, Jennifer Chow
  • Patent number: 9492819
    Abstract: This disclosure is directed to an apparatus, system and method for retrieving a target material from a suspension. A system includes a processing vessel, such as an Eppendorf tube, a syringe or a test tube, and a collector. The collector is sized and shaped to fit into a primary vessel, such as a test tube. The collector funnels the target material from the suspension through a cannula and into the processing vessel. The cannula extends into a cavity at a first end of the collector that holds the processing vessel. The collector includes a funnel at a second end in fluid communication with the cannula. In one implementation, the processing vessel includes at least one displacement fluid to be expelled, such that the at least one displacement fluid pushes the target material into the collector.
    Type: Grant
    Filed: April 1, 2015
    Date of Patent: November 15, 2016
    Assignee: RareCyte, Inc.
    Inventors: Daniel Campton, Joshua Nordberg, Steve Quarre, David Stewart, Ronald Seubert, Jonathan Lundt, Lance U'Ren
  • Publication number: 20160282242
    Abstract: This disclosure is directed to an apparatus, system and method for retrieving a target material from a sample. A first depletion agent may be added to a vessel that contains the sample to change the density of a non-target material.
    Type: Application
    Filed: June 5, 2016
    Publication date: September 29, 2016
    Applicant: RareCyte, Inc.
    Inventors: Daniel Campton, Joshua Nordberg, Steve Quarre, David Stewart, Ronald Seubert, Jonathan Lundt, Lance U'Ren, Jennifer Chow
  • Patent number: 9440234
    Abstract: This disclosure is directed to a slide for analyzing target analytes of a suspension. The slide can be used to collect and hold the target analyte for imaging or further processing. The slide comprises a well section, including wells into which the target analyte can be stored. The wells may be removable and sized to fit into a second apparatus, such as a PCR thermocycler, for additional processing. Alternatively, the wells may hold processing vessels, such as PCR tubes, the processing vessels being used for downstream processing and/or analysis.
    Type: Grant
    Filed: March 20, 2014
    Date of Patent: September 13, 2016
    Assignee: RareCyte, Inc.
    Inventors: Joshua Nordberg, Jennifer Chow, Daniel Campton, Jonathan Lundt
  • Patent number: 9417165
    Abstract: This disclosure is directed to a cap for obtaining a target analyte from a suspension. The cap introduces a magnetic field or a magnetic gradient to the tube to draw the target analyte bound to a particle to the cap. In one aspect, a cap includes a magnetic insert and a receiving piece. The magnetic insert includes a stopper and a magnet extending from the stopper; and, the receiving piece, which is configured to hold the magnetic insert, includes a receiving stopper and a sheath. The sheath may include imaging slides on opposite sides of the sheath. In another aspect, the cap may include a stopper and an embedded magnet. The cap may include an analysis piece on a bottom end of the stopper. In yet another aspect, the cap may include a fluid compartment and a filter at a bottom end of the stopper.
    Type: Grant
    Filed: July 22, 2015
    Date of Patent: August 16, 2016
    Assignee: RareCyte, Inc.
    Inventors: Daniel Campton, Jackie Stilwell, Arturo Ramirez, Jennifer Chow
  • Patent number: 9417174
    Abstract: This disclosure is directed to systems and methods for analyzing target materials of a suspension include a tube and a float. The float may include expandable portions. The system traps a target analyte between the expandable float and the tube and/or to create a seal between the expandable float and the tube to inhibit fluid from flowing past the expandable float in the tube. The expandable portions may radially expand when exposed to an expanding fluid, such that the expanding fluid is not a naturally-occurring constituent of the suspension; or, the expandable portions may radially expand when a force is exerted upon the expandable portion. A tube may include expandable portions that expand towards the float.
    Type: Grant
    Filed: January 28, 2014
    Date of Patent: August 16, 2016
    Assignee: Rarecyte, Inc.
    Inventors: Daniel Campton, Joshua Nordberg, Evan Castiglia