Patents by Inventor Daniel Capraro

Daniel Capraro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for preparing 4-amino-4-phenylpiperidines
    Patent number: 7045630
    Abstract: The invention relates to a process for preparing a 4-amino-4-phenylpiperidine (I): in which R is hydrogen or a (C1–C3)alkyl group, characterized in that a 1-protected 4-piperidone (II): in which Pr? represents a removable N-protecting group, is treated sequentially first with an alkali metal cyanide and then with an amine ENHPr? (III) in which E represents a group R?=(C1–C3)alkyl, or an N-protecting group and Pr? is an N-protecting group, the protecting group(s) being removable under the same conditions as Pr?; then the compound thus obtained (IV) is subjected to a Grignard reaction with a phenylmagnesium halide, the two or three protecting groups are removed from the compound thus obtained (V) and compound (I) is isolated or in the form of the free base, which is converted into one of its salts.
    Type: Grant
    Filed: July 15, 2002
    Date of Patent: May 16, 2006
    Assignee: Sanofi-aventis
    Inventors: Alain Alcade, Gilles Anne-Archard, Daniel Capraro
  • Method for preparing 4-amino-4-phenylpiperidines
    Publication number: 20040171837
    Abstract: The invention relates to a process for preparing a 4-amino-4-phenylpiperidine (I): 1
    Type: Application
    Filed: January 12, 2004
    Publication date: September 2, 2004
    Inventors: Alain Alcade, Gilles Anne-Archard, Daniel Capraro