Abstract: The present invention relates to compositions and methods for the treatment of the Charcot-Marie-Tooth disease and related disorders.

Abstract: Techniques are described for managing licenses of Internet of Things devices. One embodiment includes receiving, at a network management system, a request to allocate a license to a first endpoint device. Real-time device metadata and state data for the first endpoint device are accessed. Embodiments select a license instance, from a plurality of license instances, to allocate to the first endpoint device, based at least in part on the real-time device metadata and state data for the first endpoint device. The selected license instance is assigned to the first endpoint device and at least an indication that a valid license has been assigned to the first endpoint device is transmitted to the first endpoint device.

Abstract: The present invention relates to compositions and methods for the treatment of the Charcot-Marie-Tooth disease and related disorders.

Abstract: A method and system is provided for setting network policies based on electronic devices connected to a network. The electronic devices present on the network are detected and their behavior is captured using profiles. These profiles are then used to generate network policies based on the electronic devices connected to the network. Instead of reacting to behavior of the electronic devices (e.g., anomaly detection to detect malware), the method and system sets the network policies to prevent unauthorized communications (e.g., before malware is present in the system).

Abstract: Novel selective estrogen receptor degraders (SERDs) according to the formula: pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, wherein either R1 or R2 is independently selected from Cl, F, —CF3, or —CH3, and the other is hydrogen, and methods for their use are provided.

Abstract: A method and system is provided for setting network policies based on electronic devices connected to a network. The electronic devices present on the network are detected and their behavior is captured using profiles. These profiles are then used to generate network policies based on the electronic devices connected to the network. Instead of reacting to behavior of the electronic devices (e.g., anomaly detection to detect malware), the method and system sets the network policies to prevent unauthorized communications (e.g., before malware is present in the system).

Abstract: The present invention relates to compositions and methods for the treatment of the Charcot-Marie-Tooth disease and related disorders.

Abstract: Collagen compositions, methods for preparing those collagen compositions, and 3D constructs formed from those collagen compositions are provided. In particular, methods of isolating collagen that exhibits an enhanced rate of gelling, such collagen compositions, and 3D constructs formed from such collagen compositions are provided.

Abstract: Techniques are described for managing licenses of Internet of Things devices. One embodiment includes receiving, at a network management system, a request to allocate a license to a first endpoint device. Real-time device metadata and state data for the first endpoint device are accessed. Embodiments select a license instance, from a plurality of license instances, to allocate to the first endpoint device, based at least in part on the real-time device metadata and state data for the first endpoint device. The selected license instance is assigned to the first endpoint device and at least an indication that a valid license has been assigned to the first endpoint device is transmitted to the first endpoint device.

Abstract: A Group-III nitride light emitting device that utilizes scattering of hot carriers generated by Auger recombination from an externally electrically-driven, relatively narrow band gap carrier generation region into a relatively wide band gap carrier recombination region, such that the relatively wide band gap carrier recombination region of the Group-III nitride light emitting device is internally electrically injected by the hot carriers generated in the externally electrically-injected relatively narrow band gap carrier generation region. The device is used for generation of incoherent light (a light-emitting diode) or coherent light (a laser diode).

Abstract: Systems and methods for enabling communications via tablature for an application are disclosed. A system may include at least one processor configured to generate a table containing cells for holding values and enable association of a communications rule with a specific cell of the table, wherein the communications rule includes a trigger that automatically activates when a specific value in the specific cell meets a criterion. The processor may trigger the communications rule when the specific value in the specific cell meets the criterion, and communicate, upon triggering of the communications rule, a message relating to the specific value in the specific cell meeting the criterion.

Abstract: A contourable product for absorbing moisture includes a main sheet comprising an absorbent material. A number of sides of the main sheet is more than four, with the main sheet defined by a polygonal shape. The main sheet is movable between an unwrapped position and a wrapped position. In the unwrapped position, the main sheet is completely unfolded and substantially flat. In the wrapped position, the main sheet is contoured to secure to and wrap around a human head and extend around head hair of the human head.

Abstract: A method of removing a substrate, comprising: forming a growth restrict mask with a plurality of striped opening areas directly or indirectly upon a GaN-based substrate; and growing a plurality of semiconductor layers upon the GaN-based substrate using the growth restrict mask, such that the growth extends in a direction parallel to the striped opening areas of the growth restrict mask, and growth is stopped before the semiconductor layers coalesce, thereby resulting in island-like semiconductor layers. A device is processed for each of the island-like semiconductor layers. Etching is performed until at least a part of the growth restrict mask is exposed. The devices are then bonded to a support substrate. The GaN-based substrate is removed from the devices by a wet etching technique that at least partially dissolves the growth restrict mask. The GaN substrate that is removed then can be recycled.

Abstract: Provided herein are novel 10Fn3 domains which specifically bind to PD-L1, as well as imaging agents based on the same for diagnostics.

Abstract: A method of removing a substrate, comprising: forming a growth restrict mask with a plurality of striped opening areas directly or indirectly upon a GaN-based substrate; and growing a plurality of semiconductor layers upon the GaN-based substrate using the growth restrict mask, such that the growth extends in a direction parallel to the striped opening areas of the growth restrict mask, and growth is stopped before the semiconductor layers coalesce, thereby resulting in island-like semiconductor layers. A device is processed for each of the island-like semiconductor layers. Etching is performed until at least a part of the growth restrict mask is exposed. The devices are then bonded to a support substrate. The GaN-based substrate is removed from the devices by a wet etching technique that at least partially dissolves the growth restrict mask. The GaN substrate that is removed then can be recycled.

Abstract: A method and system is provided for setting network policies based on electronic devices connected to a network. The electronic devices present on the network are detected and their behavior is captured using profiles. These profiles are then used to generate network policies based on the electronic devices connected to the network. Instead of reacting to behavior of the electronic devices (e.g., anomaly detection to detect malware), the method and system sets the network policies to prevent unauthorized communications (e.g., before malware is present in the system).

Abstract: Vertical Cavity Surface Emitting Laser (VCSEL) configurations are disclosed. In a first example, the VCSEL includes a III-Nitride active region between a p-type III-Nitride layer and an n-type III-Nitride layer; and a curved minor on or above the p-type III-Nitride layer. The curved mirror can be formed in a III-Nitride layer or a Transparent Oxide (TO) material and enables the formation of a long VCSEL cavity that improves VCSEL lifetime, VCSEL output power, VCSEL power efficiency and VCSEL reliability. In a second example, the VCSEL has an active region with a high indium content. In a third example, the VCSEL is transparent.

Abstract: A respirator system includes a hood, a breathing tube, and an air purification device. The breathing tube is coupled to the hood and has an inner surface coated in an antimicrobial coating. The air purification device is coupled to the breathing tube and is further configured to deliver filtered air to the hood via the breathing tube. The air purification device includes a housing, a back pad, a filter, a fan, a power source, and a controller. The housing includes a front housing component and a rear housing component. The back pad is configured to provide a cushion between the rear housing component and the user's body. The fan is configured to pull ambient air through the filter and deliver the filtered air to the hood. The power source is configured to supply power to the fan. The controller is configured to regulate a speed of the fan.

Abstract: A contourable product for absorbing moisture includes a main sheet comprising an absorbent material. A number of sides of the main sheet is more than four, with the main sheet defined by a polygonal shape. The main sheet is movable between an unwrapped position and a wrapped position. In the unwrapped position, the main sheet is completely unfolded and substantially flat. In the wrapped position, the main sheet is contoured to secure to and wrap around a human head and extend around head hair of the human head.