Patents by Inventor Daniel Cravo

Daniel Cravo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMBINATION OF TRAZINE DERIVATIVES AND INSULIN SECRETION STIMULATORS
    Publication number: 20100233255
    Abstract: The present patent application relates to novel combinations of a triazine derivative and of an insulin secretion stimulator.
    Type: Application
    Filed: December 18, 2006
    Publication date: September 16, 2010
    Inventors: Gérard Moinet, Daniel Cravo, Didier Mesangeau
  • PYRIDINE DERIVATIVES USEFUL AS GLUCOKINASE ACTIVATORS
    Publication number: 20100216794
    Abstract: Novel heterocyclic compounds of the formula I in which R1, R2, R3, R4 and D have the meanings indicated in claim 1, are activators of glucokinase and can be used for the prevention and/or treatment of Diabetes Typ 1 and 2, obesity, neuropathy and/or nephropathy.
    Type: Application
    Filed: August 13, 2008
    Publication date: August 26, 2010
    Inventors: Lars Thore Burgdorf, Norbert Beier, Johannes Gleitz, Christine Charon, Daniel Cravo
  • Dihydro-1,3,5-triazine amine derivatives and their therapeutic uses
    Patent number: 7767676
    Abstract: The invention relates to the compounds of general formula (I): in which R1, R2, R3, R4, R5 and R6 are as defined in Claim 1. These compounds can be used in the treatment of pathological conditions associated with the insulin-resistance syndrome.
    Type: Grant
    Filed: October 30, 2007
    Date of Patent: August 3, 2010
    Assignee: Merck Sante
    Inventors: Gerard Moinet, Daniel Cravo, Liliane Doare, Micheline Kergoat, Didier Mesangeau
  • USE OF TRIAZINE DERIVATIVES FOR THE MANUFACTURE OF A MEDICAMENT HAVING A CICATRISING OR ANGIOGENIC EFFECT
    Publication number: 20100168115
    Abstract: The present patent application relates to the use of triazine derivatives as cicatrising or angiogenic agents, wherein the triazine is a molecule of formula (I).
    Type: Application
    Filed: December 18, 2006
    Publication date: July 1, 2010
    Inventors: Gérard Moinet, Daniel Cravo
  • COMBINATION OF TRIAZINE DERIVATIVES AND PPARalpha AGONISTS
    Publication number: 20100159005
    Abstract: The present patent application relates to combinations of triazine derivatives and of PPAR? agonists.
    Type: Application
    Filed: December 18, 2006
    Publication date: June 24, 2010
    Inventors: Gérard Moinet, Daniel Cravo, Didier Mesangeau
  • COMBINATION OF TRIAZINE DERIVATIVES AND HMG-COA REDUCTASE INHIBITORS
    Publication number: 20100158999
    Abstract: The present patent application relates to combinations of a triazine derivative with an HMG-CoA reductase inhibitor.
    Type: Application
    Filed: December 18, 2006
    Publication date: June 24, 2010
    Inventors: Gérard Moinet, Daniel Cravo, Didier Mesangeau
  • Process for resolving aimines that are useful for the treatment of disorders associated with insulin resistance syndrome
    Patent number: 7501511
    Abstract: The present invention is directed towards a process for resolving a racemic amino compound derived from dihydro-1,3,5-triazines. The invention is also directed towards the enantiomers of amino derivatives of dihydro-1,3,5-triazines and to their use for the preparation of medicaments, in particular for the treatment of diabetes and malaria.
    Type: Grant
    Filed: April 6, 2004
    Date of Patent: March 10, 2009
    Assignee: Merck Patent GmbH
    Inventors: Gérard Moinet, Daniel Cravo, Thierry Passemar
  • Bicyclic guanidine derivatives and therapeutic uses thereof
    Patent number: 7491733
    Abstract: The invention relates to compounds of general formula (I), in which A, X, Y and R1 are defined in Claim 1. These compounds may be used in the treatment of pathologies associated with insulin resistane syndrome.
    Type: Grant
    Filed: February 27, 2002
    Date of Patent: February 17, 2009
    Assignee: Merck Patent GmbH
    Inventors: Gerard Moinet, Daniel Cravo
  • Dihydro-1,3,5-triazine amine derivatives and their therapeutic uses
    Patent number: 7452883
    Abstract: The invention concerns compounds of general formula (I) wherein: R1, R2, R3, R4, R5 and R6 are as defined in Claim 1. The compounds are useful in the treatment of pathologies related to the insulin-resistance syndrome.
    Type: Grant
    Filed: March 22, 2005
    Date of Patent: November 18, 2008
    Assignee: Merck Sante
    Inventors: Gerard Moinet, Daniel Cravo, Liliane Doare, Micheline Kergoat, Didier Mesangeau
  • Dihydro-1,3,5-triazine amine derivatives and their therapeutic uses
    Publication number: 20080108619
    Abstract: The invention relates to the compounds of general formula (I): in which R1, R2, R3, R4, R5 and R6 are as defined in Claim 1. These compounds can be used in the treatment of pathological conditions associated with the insulin-resistance syndrome.
    Type: Application
    Filed: October 30, 2007
    Publication date: May 8, 2008
    Applicant: MERCK SANTE
    Inventors: Gerard Moinet, Daniel Cravo, Liliane Doare, Micheline Kergoat, Didier Mesangeau
  • Dihydro-1,3,5-triazine amine derivatives and their therapeutic uses
    Publication number: 20080108591
    Abstract: The invention relates to the compounds of general formula (I): in which R1, R2, R3, R4, R5 and R6 are as defined in claim 1. These compounds can be used in the treatment of pathological conditions associated with the insulin-resistance syndrome.
    Type: Application
    Filed: October 31, 2007
    Publication date: May 8, 2008
    Applicant: MERCK SANTE
    Inventors: Gerard Moinet, Daniel Cravo, Liliane Doare, Micheline Kergoat, Didier Mesangeau
  • Biguanide derivatives
    Patent number: 7285681
    Abstract: The present invention relates to biguanide derivatives of formula (I), wherein R1, R2, R3 and R4 have the meanings as given in claim (1). Compounds are useful in the treatment of pathologies associated with hyperglycaemia, such as diabetes.
    Type: Grant
    Filed: March 20, 2002
    Date of Patent: October 23, 2007
    Assignee: Merck Patent Gesellschaft
    Inventors: Gerard Moinet, Daniel Cravo
  • Process for resolving aimines that are useful for the treatment of disorders associated with insulin resistance syndrome
    Publication number: 20060223803
    Abstract: The present invention is directed towards a process for resolving a racemic amino compound derived from dihydro-1,3,5-triazines. The invention is also directed towards the enantiomers of amino derivatives of dihydro-1,3,5-triazines and to their use for the preparation of medicaments, in particular for the treatment of diabetes and malaria.
    Type: Application
    Filed: April 6, 2004
    Publication date: October 5, 2006
    Inventors: Gérard Moinet, Daniel Cravo, Thierry Passemar
  • Dihydro-1,3,5-triazine amine derivatives and their therapeutic uses
    Patent number: 7034021
    Abstract: The invention concerns compounds of general formula (I) wherein: R1, R2, R3, R4, R5 and R6 are as defined in Claim 1. Said compounds are useful in the treatment of pathologies related to the insulin-resistance syndrome.
    Type: Grant
    Filed: January 25, 2001
    Date of Patent: April 25, 2006
    Assignee: LIPHA
    Inventors: Gérard Moinet, Daniel Cravo, Liliane Doare, Micheline Kergoat, Didier Mesangeau
  • Dihydro-1,3,5-triazine amine derivatives and their therapeutic uses
    Publication number: 20050165022
    Abstract: The invention concerns compounds of general formula (I) wherein: R1, R2, R3, R4, R5 and R6 are as defined in Claim 1. The compounds are useful in the treatment of pathologies related to the insulin-resistance syndrome.
    Type: Application
    Filed: March 22, 2005
    Publication date: July 28, 2005
    Applicant: LIPHA
    Inventors: Gerard Moinet, Daniel Cravo, Liliane Doare, Micheline Kergoat, Didier Mesangeau
  • Bicyclic guanidine derivatives and therapeutic uses thereof
    Publication number: 20040122040
    Abstract: The invention relates to compounds of general formula (I), in which A, X, Y and R1 are delined in claim 1. These compounds may be used in the treatment of pathologies associated with insulin resistane syndrome.
    Type: Application
    Filed: September 22, 2003
    Publication date: June 24, 2004
    Inventors: Gerard Moinet, Daniel Cravo
  • Biguanide derivatives
    Publication number: 20040092495
    Abstract: The present invention relates to biguanide derivatives of formula (I), wherein R1, R2, R3 and R4 have the meanings as given in claim (1). Compounds are useful in the treatment of pathologies associated with hyperglycaemia, such as diabetes.
    Type: Application
    Filed: September 22, 2003
    Publication date: May 13, 2004
    Inventors: Gerard Moinet, Daniel Cravo
  • Dihydro-1,3,5-triazine amine derivatives and their therapeutic uses
    Publication number: 20030109530
    Abstract: The invention concerns compounds of general formula (I) wherein: R1, R2, R3, R4, R5 and R6 are as defined in claim 1. Said compounds are useful in the treatment of pathologies related to the insulin-resistance syndrome.
    Type: Application
    Filed: July 15, 2002
    Publication date: June 12, 2003
    Inventors: Gerard Moinet, Daniel Cravo, Liliane Doare, Micheline Kergoat, Didier Mesangeau
  • (Aminoiminomethyl) amino) alkane-carboxamides and their applications in therapy
    Patent number: 6518458
    Abstract: The invention to a pharmaceutical composition comprising as active principle a compound of general formula (I), in which R1, R2, R3, and A are as defined in claim 1. These compositions can be used in the treatment of pathologies associated with insulin resistance syndrome.
    Type: Grant
    Filed: July 10, 2001
    Date of Patent: February 11, 2003
    Assignee: Merck Patent GmbH
    Inventors: Gérard Moinet, Daniel Cravo, Didier Mesangeau, Liliane Doare, Micheline Kergoat