Patents by Inventor Daniel Cua

Daniel Cua has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • P116 ANTIBODIES
    Publication number: 20220363756
    Abstract: The present invention provides antibodies and antigen-binding fragments thereof that bind PI16 and block binding of ILT3 to PI16.
    Type: Application
    Filed: May 16, 2022
    Publication date: November 17, 2022
    Applicant: Merck Sharp & Dohme LLC
    Inventors: Daniel Cua, Holly Cherwinski, Adele Wang, Yi Chen, Barbara Joyce-Shaikh
  • ILT3 ligand
    Patent number: 11370839
    Abstract: The present invention provides antibodies and antigen-binding fragments thereof that bind ILT3, ILT3 ligand (i.e., PI16) or a complex between ILT3 and the ILT3 ligand. Methods for determining whether ILT3 and the ILT3 ligand bind together or whether a substance agonizes or antagonizes such binding are also provided.
    Type: Grant
    Filed: November 10, 2017
    Date of Patent: June 28, 2022
    Assignee: MERCK SHARP & DOHME CORP.
    Inventors: Daniel Cua, Holly Cherwinski, Adele Wang, Yi Chen, Barbara Joyce-Shaikh
  • ILT3 LIGAND
    Publication number: 20190241655
    Abstract: The present invention provides antibodies and antigen-binding fragments thereof that bind ILT3, ILT3 ligand (i.e., PI16) or a complex between ILT3 and the ILT3 ligand. Methods for determining whether ILT3 and the ILT3 ligand bind together or whether a substance agonizes or antagonizes such binding are also provided.
    Type: Application
    Filed: November 6, 2017
    Publication date: August 8, 2019
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Daniel Cua, Holly Cherwinski, Adele Wang, Yi Chen, Barbara Joyce-Shaikh
  • METHOD FOR PREPARING ANTIBODIES HAVING IMPROVED PROPERTIES
    Publication number: 20140286946
    Abstract: The present invention is directed to methods and compositions for the production of Fc-containing polypeptides having improved properties.
    Type: Application
    Filed: October 26, 2012
    Publication date: September 25, 2014
    Inventors: Terrance A. Stadheim, Daniel Cua, Dongxing Zha
  • Uses of mammalian cytokine; related reagents
    Publication number: 20060140950
    Abstract: Provided are methods of treatment for inflammatory and autoimmune disorders of the central nervous system and gastrointestinal tract. Also provided are methods of diagnosis.
    Type: Application
    Filed: February 21, 2006
    Publication date: June 29, 2006
    Applicant: Schering Corporation
    Inventors: Daniel Cua, Yi Chen, Robert Kastelein, Claire Langrish, Donna Rennick, Jonathon Sedgwick
  • Uses of mammalian cytokine; related reagents
    Publication number: 20060134112
    Abstract: Provided are methods of treatment for inflammatory and autoimmune disorders of the metabolic system. Also provided are methods of diagnosis.
    Type: Application
    Filed: December 16, 2005
    Publication date: June 22, 2006
    Applicant: Schering Corporation
    Inventors: Daniel Cua, Robert Kastelein
  • Methods of modulating cytokine activity; related reagents
    Publication number: 20050208052
    Abstract: Provided are methods of modulating cytokine activity, e.g., for the purpose of treating viral infections. Also provided are reagents for use in screening for agonists or antagonists of IL-23.
    Type: Application
    Filed: February 15, 2005
    Publication date: September 22, 2005
    Applicant: Schering Corporation
    Inventors: Peter Katsikis, Ioannis Dimitriou, Daniel Cua