Abstract: A system for pulsed power drilling a wellbore into a subsurface formation comprises a drill bit that includes at least one electrode coupled to a power source, the at least one electrode to periodically emit an electrical discharge based on electrical pulses received from the power source. The system comprises a first port to output a first type of drilling fluid having a different composition than a second type of drilling fluid to flow downhole for removal of cuttings, wherein the electrical discharge is to be transmitted through the first type of drilling fluid and through a rock of the subsurface formation, wherein an additive or a property of at least one of the first type of drilling fluid or the second type of drilling fluid reduces mixability between the first type of drilling fluid and the second type of drilling fluid.

Abstract: The object of the present invention is a novel class of compounds and the pharmaceutical compositions containing them as active ingredients. The compounds according to the invention are effective in the prevention or treatment of disorders directly involving the urokinase system, its receptor and its natural inhibitor (uPA, uPAR and PAI), and/or indirectly involving its co-receptors such as formyl-peptide receptors (FPRs), integrins and vascular endothelial growth factor (VEGF).

Abstract: Provided herein are methods and systems of molecular profiling of diseases, such as cancer. In some embodiments, the molecular profiling can be used to identify treatments for a disease, such as treatments that were not initially identified as a treatment for the disease or not expected to be a treatment for a particular disease.

Abstract: A fiber optic ferrule has a set of optical fiber support structures that includes a slotted blind hole to assist in the application of epoxy to the optical fibers and fiber optic ferrule. There is an entrance surface within the slotted blind holes against which the optical fibers may be disposed. The slotted blind holes may be formed within a portion of a first wall and a second wall adjacent a front end of the fiber optic ferrule.

Abstract: A road taping machine is configured to unspool road marking tape from a spool and tamp that tape onto pavement via a tamping roller. Tape is cut using a blade assembly, and aligned with several alignment rollers. A pivot arm permits a subset of the alignment rollers to displace, allowing slack in the tape to be taken in during cutting such that taping can occur continuously, despite cuts. The spool is housed on an axle anchored to a support arm that can be actuated between an elevated position for loading, and a depressed position for taping. A taping section of the machine is laterally displaceable relative to a drive section via a displacement plate, to permit taping of laterally remote locations. The machine can support multiple spools, including spools with tape paths that bypass the blade assembly.

Abstract: In an embodiment, a system is configured to replay and/or reconstruct execution events and system states in real time or substantially in real time starting from the point when execution of a target program has stopped to the point when the user desires to step through the target program's execution in order to debug the software. In an embodiment, a system is configured to efficiently collect trace data that is sufficient to reconstruct the state of a computer system at any point of time from the start of execution to the time execution was stopped. Efficient and effective debugging of the software can be performed using embodiments of the disclosed methods, systems, and devices.

Abstract: A laptop computer may have a lower housing with an antenna module. The antenna module may include first and second pieces of sheet metal that form a cavity. The cavity may have an aperture covered by a dielectric layer. The first piece of sheet metal may be bent towards the second piece and may be welded to the second piece at a side of the cavity opposite the aperture. An antenna arm may be disposed within the cavity and mounted to the second piece. The antenna arm may be laterally separated from the dielectric layer by a non-zero distance. A dielectric loading block may be disposed within the cavity and mounted to the second piece. The antenna arm may be mounted to a side of the dielectric loading block facing the aperture and the dielectric layer. The antenna arm may convey radio-frequency signals through the aperture and the dielectric layer.

Abstract: A line launcher includes a launcher body extending along a longitudinal axis between a rear end and a front end. The line launcher further includes a handle, a trigger, and a removable battery. The line launcher further includes a compressed gas charge assembly. The line launcher further includes an elongated barrel coupled to the body at the front end. The line launcher further includes a throwline assembly, the throwline assembly including a projectile and a throwline, the projectile insertable into and ejectable from the elongated barrel.

Abstract: The present disclosure provides an apparatus for post-curing an article, as well as a system, methods, and post-cured articles. The apparatus includes a housing, a chamber disposed in the housing, at least two light emitting diodes (LEDs) disposed within the housing, and a user interface disposed on an exterior of the housing. The chamber is adaptable to each of an open, closed, and hermetically sealed configuration. The chamber includes a material transparent to actinic radiation and light from the LEDs enters the chamber from more than one direction. The user interface includes a display and program switches configured to adjust at least three operational parameters of the apparatus. The apparatus further includes a vacuum pump operatively coupled to the chamber. The system includes the apparatus and an article. An article includes layers of at least one photopolymerized crosslinked composition and a low extractable component content.

Abstract: A magnetometer-based metal detection device and methods of use are described. The device includes a proximal portion, a central body and a distal portion, and at least one magnetometer positioned within or on the distal portion. The at least one magnetometer includes at least one sensor capable of sensing a magnetic field in three orthogonal axes. Also described is a method of calibrating the device to achieve rotational invariance, and a method of determining a directionality or directional line along which a target metal object lies.

Abstract: A new fiber optic ferrule has an alignment structure on a surface through which light passes. The alignment structure is preferably in the shape of a dog bone, allowing the alignment structure to align the fiber optic ferrule in a receptacle while reducing the influence of temperature on the alignment.

Abstract: A combined multi-lumen sheath with a wire body and a filter. The filter may be removably coupled to the multi-lumen sheath within a filter capsule for temporary placement and retrieval.

Abstract: Aspects of the invention are directed to coil positioning apparatuses, systems, and methods of employing the same. One portable head coil apparatus is provided for use with a magnetic resonance imaging system. The portable head coil apparatus includes a base having at least one coil array comprising at least two coil elements. The base is positionable relative to the patients head and has a receiving portion defining a receiving surface positionable adjacent the patient positioning device. The portable head coil apparatus includes an extension movable relative to the base and having at least one coil array comprising at least two coil elements. The extension defines an inner surface having a curvature the degree of which is greater than that of the receiving surface of the base. The inner surface of the extension and the receiving surface of the base together at least partially define an imaging region therebetween.

Abstract: A method and apparatus for filtering fluid for a food processing system is disclosed and includes a fluid inlet, a filtered outlet, a drain outlet, two filters—each having inlets, inlet valves, drain outlets, drain valves, filtered outlets, and return valves. A first recycling flow path includes an inlet valve, an inlet, a filter, a return valve, and a filtered outlet. A first drain flow path includes the inlet valve, the inlet, the filter, the drain valve, and the drain outlet. A second set of like flow paths for the second filter is provided. A controller is connected to control each of valves, and the controller has a first filter purge module, a first filter filter module, a first filter power purge module, a first filter off module, second filter purge module, a second filter filter module, a second filter power purge module, and a second filter off module.

Abstract: A manually powered treadmill includes a front rotatable element and a rear rotatable element coupled to a frame; a bearing assembly at least partially supporting one of the front or rear rotatable elements; and a running belt disposed about the front and rear rotatable elements. The bearing assembly includes a predefined low viscosity bearing fluid. The running belt defines a non-planar running surface. The running belt includes a first endless belt and a plurality of slats, each slat having a first side and a second side and coupled to the first endless belt. Each slat in the plurality of slats defines at least one aperture, and the at least one aperture is structured to receive a fastener to facilitate coupling to the first endless belt.

Abstract: A process for combusting a high-moisture fuel to generate steam, the process comprising heating a high-moisture solid fuel while contacting the high-moisture solid fuel with an oxygen-depleted gas stream to produce a dried solid fuel and a moist oxygen-depleted gas stream; combusting the dried solid fuel with a combustion air stream to produce a combustion products stream; transferring heat to generate steam by indirect heat exchange with the combustion products stream; dividing the combustion products stream into a first portion and a second portion; transferring heat to the recirculating thermal fluid by indirect heat exchange with the first portion of the combustion products stream; and transferring heat to preheat the combustion air stream by indirect heat exchange with the second portion of the combustion products stream; and recombining the first portion of combustion products stream and the second portion of the combustion products stream.

Abstract: The invention describes the use of polyphenols and polyamino derivatives adjacent to absorber layers on the basis of small molecules in organic optoelectronic components.

Abstract: The apparatus (1000) includes a housing (110), a chamber (120) disposed in the housing, at least two light emitting diodes (LEDs) (130) disposed within the housing (110), and a user interface (140) disposed on an exterior (112) of the housing. The chamber (120) is adaptable to each of an open, closed, and hermetically sealed configuration. The chamber (120) includes a material transparent to actinic radiation and light from the LEDs (130) enters the chamber from more than one direction. The user interface (140) includes a display (142) and program switches (144) configured to adjust at least three operational parameters of the apparatus. The apparatus (1000) further includes a vacuum pump (150) operatively coupled to the chamber (120). The system includes the apparatus (1000) and an article (180). An article includes layers of at least one photopolymerized crosslinked composition and a low extractable component content.

Abstract: A leg strap adapter may include a leg strap adapter plate, an attachment member, and at least two slots configured to receive a strap. The leg strap adapter is configured to be rotatably attached to a belt engaging member by the attachment member and the belt engaging member is configured to mount a holster. The attachment member may include a central post projecting distally from the user distal face of the leg strap adapter plate, and at least one radial protrusion projecting radially from the central post. The attachment member may be configured to engage with a corresponding at least one opening comprised on the belt engaging member.