Patents by Inventor Daniel D. Kephart

Daniel D. Kephart has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Simultaneous isolation and quanitation of DNA
    Publication number: 20040086930
    Abstract: The present invention provides methods for isolating a defined quantity of DNA target material from other substances in a medium. The method may be carried out using a known quantity of a silica-containing solid support, such as silica magnetic particles, having a definable capacity for reversibly binding DNA target material, and DNA target material in excess of the binding capacity of the particles. The methods of the present invention involve forming a complex of the silica magnetic particles and the DNA target material in a mixture of the medium and particles, and separating the complex from the mixture using external magnetic force. The DNA target material may then be eluted from the complex. The quantity of DNA target material eluted may be determined based on a calibration model. The methods of the present invention permit isolation of DNA target material which is within a known quantity range.
    Type: Application
    Filed: October 27, 2003
    Publication date: May 6, 2004
    Applicant: Promega Corporation
    Inventors: Allan M. Tereba, Rex M. Bitner, Susan C. Koller, Craig E. Smith, Daniel D. Kephart, Steven J. Ekenberg
  • Simultaneous isolation and quantitation of DNA
    Patent number: 6673631
    Abstract: The present invention provides methods for isolating a defined quantity of DNA target material from other substances in a medium. The method may be carried out using a known quantity of a silica-containing solid support, such as silica magnetic particles, having a definable capacity for reversibly binding DNA target material, and DNA target material in excess of the binding capacity of the particles. The methods of the present invention involve forming a complex of the silica magnetic particles and the DNA target material in a mixture of the medium and particles, and separating the complex from the mixture using external magnetic force. The DNA target material may then be eluted from the complex. The quantity of DNA target material eluted may be determined based on a calibration model. The methods of the present invention permit isolation of DNA target material which is within a known quantity range.
    Type: Grant
    Filed: August 20, 1999
    Date of Patent: January 6, 2004
    Assignee: Promega Corporation
    Inventors: Allan M. Tereba, Rex M. Bitner, Susan C. Koller, Craig E. Smith, Daniel D. Kephart, Steven J. Ekenberg