Patents by Inventor Daniel D. Sternbach

Daniel D. Sternbach has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Preparation of water soluble camptothecin derivatives
    Patent number: 5342947
    Abstract: The present invention relates to the synthesis of water soluble, camptothecin derivatives of formula (I), ##STR1## wherein: n represents the integer 1 or 2;R.sup.1 represents independently, hydrogen, lower alkyl, (C.sub.3-7)cycloalkyl, (C.sub.3-7)cycloalkyl lower alkyl, lower alkenyl, hydroxy lower alkyl, lower alkoxy lower alkyl; andR.sup.2 represents hydrogen andthe pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: October 9, 1992
    Date of Patent: August 30, 1994
    Assignee: Glaxo Inc.
    Inventors: Karen Lackey, Daniel D. Sternbach
  • Process for the synthesis of cyclopentene derivatives of purines
    Patent number: 5144034
    Abstract: This invention relates to a new process for preparing certain optically active cyclopentene derivatives and novel intermediates used in this process. In particular, the invention concerns the synthesis of the 1'R-cis isomer of carbovir, (1'R-cis)-2-amino-1,9-dihydro-9[4-(hydroxymethyl)-2-cyclopenten-1-yl]-6H-p urin-6-one, an antiviral agent.
    Type: Grant
    Filed: April 6, 1990
    Date of Patent: September 1, 1992
    Assignee: Glaxo Inc.
    Inventors: M. Ross Johnson, Michael R. Peel, Daniel D. Sternbach