Patents by Inventor Daniel Danila

Daniel Danila has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Gene expression profile associated with prostate cancer
    Patent number: 10030271
    Abstract: Using an RT-PCR platform, detection of gene transcripts highly expressed in prostate tissue and expressed in peripheral blood mononuclear cells (PBMC) from patients with mCRPC can provide a more reliable and robust prediction of poor overall survival than that of CTC enumeration in mCRPC. Disclosed is the identification of five genes, KLK3, KLK2, HOXB13, GHRL2 and FOXA1, the detection of two (2) or more transcripts of which predicts overall poor survival. The test is performed on blood samples that have been collected in collection tubes that stabilize intracellular RNA, require minimal on-site processing and can be easily stored and shipped for subsequent extraction of total RNA from whole blood for RT-PCR.
    Type: Grant
    Filed: August 19, 2013
    Date of Patent: July 24, 2018
    Assignee: MEMORIAL SLOAN-KETTERING CANCER CENTER
    Inventors: Howard Scher, Martin Fleisher, Daniel Danila
  • GENE EXPRESSION PROFILE ASSOCIATED WITH PROSTATE CANCER
    Publication number: 20150191792
    Abstract: Using an RT-PCR platform, detection of gene transcripts highly expressed in prostate tissue and expressed in peripheral blood mononuclear cells (PBMC) from patients with mCRPC can provide a more reliable and robust prediction of poor overall survival than that of CTC enumeration in mCRPC. Disclosed is the identification of five genes, KLK3, KLK2, HOXB13, GHRL2 and FOXA1, the detection of two (2) or more transcripts of which predicts overall poor survival. The test is performed on blood samples that have been collected in collection tubes that stabilize intracellular RNA, require minimal on-site processing and can be easily stored and shipped for subsequent extraction of total RNA from whole blood for RT-PCR.
    Type: Application
    Filed: August 19, 2013
    Publication date: July 9, 2015
    Applicant: MEMORIAL SLOAN-KETTERING CANCER CENTER
    Inventors: Howard Scher, Martin Fleisher, Daniel Danila
  • HIGH EFFICIENCY AND RELIABLE FUEL CELL SYSTEM OPERATING AT NEAR 100% FUEL UTILIZATION
    Publication number: 20120034539
    Abstract: A fuel cell system 110 containing fuel cells 120 contacted by hydrogen containing gaseous fuel, generating spent gaseous depleted fuel which is recirculated to a hydrogen separation system 143, preferably a heat exchanger 144 and condenser 148 to remove water 150, after which it is mixed with fresh fuel 116 and recirculated to the fuel cells 120.
    Type: Application
    Filed: August 4, 2010
    Publication date: February 9, 2012
    Inventors: Raymond George, Arun K.S. Iyengar, Daniel Danila, Wayne Lundberg
  • Method and apparatus for a powder metallurgical process
    Patent number: 5812924
    Abstract: A method of producing a green compact which includes the steps of forming a generally homogeneous powder blend of powder components; consolidating the powder blend into a green body wherein the green body includes a flashing; impinging the green body with a fluid stream so as to dislodge the flashing; and removing the dislodged flashing from the surface of the green body.
    Type: Grant
    Filed: November 4, 1997
    Date of Patent: September 22, 1998
    Assignee: Kennametal Inc.
    Inventors: William R. Shaffer, Thomas J. Baric, Daniel Danila, Robert L. Macabobby