Abstract: An accessory mount assembly includes a drive slide and a guide. The drive slide is connected to and linearly guided along the guide. A link is rotationally connected to the drive slide. A drive screw engages the drive slide to drive the drive slide. A mount is pivotably mounted and the mount is connected to the link to be pivoted by the link via a movement of the drive slide.

Abstract: An apparatus for use in a power delivery system, the apparatus comprising: a DC circuit breaker having first and second terminals and configured to automatically switch from a closed state to an open state during an overcurrent condition; a disconnector switch in series with the DC circuit breaker, the disconnector switch having a first terminal for connecting to a first polarity terminal of a DC power supply, a second terminal for connecting to a second polarity terminal of the DC power supply and a common terminal connected to the first terminal of the DC circuit breaker, the disconnector switch having at least a first position in which the first terminal is connected to the common terminal and a second position in which the second terminal is connected to the common terminal; and an interlock mechanism coupled to the DC circuit breaker and the disconnector switch, the interlock mechanism configured to disable the DC circuit breaker from automatically switching from the closed state to the open state during

Abstract: A cooling manifold assembly configured to deliver cutting fluid includes a manifold body with a coupling for fastening the manifold body to a non-movable portion of a device configured to hold and rotate a workpiece around a central rotational axis of a guide bushing or collet of the device, where the manifold body surrounds at least a portion of the central rotational axis. A first inlet is fluidly coupled to a first channel defined in the manifold body, and a plurality of first outlets of the manifold body are fluidly coupled to the first inlet such that the plurality of first outlets are configured to direct the cutting fluid at a plurality of positions around the central rotational axis at one or a plurality of discharge angles such that the cutting fluid contacts the workpiece and is transmitted away from the guide bushing or collet of the device.

Abstract: Three-dimensional (3D) information is generated from two or more two-dimensional (2D) images. In the 2D images, one or more objects are identified, and either a corresponding portion of the 3D information representing the same object is identified and/or where the 3D information is corrected correspondingly. The correction may be the leaving out of 3D information representing the object or the correction of the 3D information based on knowledge of a shape of the object.

Abstract: Controlling provision of a set of utilities by a financial institution. The method includes receiving, by a processor of a financial institution computing system associated with a financial institution, utility usage information from a set of utility meters associated with a plurality of customers of the utility company. The method includes determining a utility account balance for a customer of the plurality of customers based at least in part by an aggregate amount of utility usage used by the plurality of customers for a billing cycle by aggregating the received utility usage information for the billing cycle. The method includes determining that the utility account balance exceeds a threshold permitted past due amount. The method includes sending a stop signal to a utility meter associated with the customer, the stop signal instructing the utility meter to cut off provision of the utility to a property serviced by the utility meter.

Abstract: A powder inhaler includes a casing having a mouthpiece and housing an inhalation channel connected to an opening of the mouthpiece, a container for storing a powdered medicament and placed in the casing, a cover engageable with the casing to close the mouthpiece. The cover includes a sealing element made of a material that is more deformable than a material of the mouthpiece such that, when the cover is engaged with the casing and closes the mouthpiece, a main portion of the sealing element is coupled to the opening to tight close the opening.

Abstract: The invention relates to therapeutic compositions, solid oral dosage forms, and methods for treating, preventing, or alleviating lower urinary tract symptoms (LUTS), benign prostatic hyperplasia (BPH), erectile dysfunction (ED), urinary incontinence, bladder obstruction, overactive bladder (OAB), underactive bladder, interstitial cystitis, prostatitis, bladder and prostate inflammation, prostate fibrosis or pelvic pain. The therapeutic compositions can comprise cranberry powder enriched in cranberry seeds or cranberry seed meal.

Abstract: A drug product includes a multidose dry powder inhalation device. The device has a medicament chamber and a desiccant chamber adjacent to the medicament chamber, and a pharmaceutical composition therein. The pharmaceutical composition includes a pharmaceutically acceptable salt of tanimilast. The desiccant chamber is filled with molecular sieves.

Abstract: A drive train for a wind-up injection device, comprises a torsional energy storage adapted to be loaded or unloaded by a rotatable element, a rotatable user handle coupled with a button, a rotationally drivable expelling mechanism, and a clutch element coupled with the torsional energy storage via the rotatable element and comprising a ratchet for maintaining the rotatable element at one of a number of discrete angular positions, wherein via the rotatable element, the clutch element is adapted to transmit a torque from the user handle to the torsional energy storage or from the torsional energy storage to the expelling mechanism, and wherein the ratchet is switchable from one position to an adjacent position by a torque transmitted from the user handle to the torsional energy storage, and wherein the drive train is adapted to dampen torque peaks by a flexible impact portion in the area of the clutch element.

Abstract: A powder inhaler includes a casing having a mouthpiece, an inhalation channel, a container for a powdered medicament, and a metering device with a shuttle having a dosing recess. The shuttle is movable between a filling position, in which the dosing recess is in alignment with an opening of the container to be filled with a dose of the powdered medicament, and an inhalation position, in which the dosing recess is in alignment with the inhalation channel, for enabling inhalation of the dose of the powdered medicament contained in the dosing recess through the mouthpiece. A sealing device is operationally active at a coupling zone of the shuttle with the container when the shuttle is in the filling position, the coupling zone circumscribing the dosing recess and the opening.

Abstract: The present disclosure provides binding agents, such as antibodies, that specifically bind ILT3, including human ILT3, as well as compositions comprising the binding agents, and methods of their use. The disclosure also provides related polynucleotides and vectors encoding the binding agents and cells comprising the binding agents.

Abstract: An elevator tractive drive system including a plurality of wheels coupled to an elevator cab. The plurality of wheels are configured to compress into one or more shaft-mounted rails and/or one or more interior shaft wall surfaces. The plurality of wheels are powered by one or more motors coupled to a transmission configured to deliver regulated torque to the plurality of wheels. The system includes various sensors to measure parameters related to kinematics of the cab and/or the plurality of wheels, parameters related to a mass or a weight of the elevator cab and any pay load and/or parameters related to compressive forces generated at a wheel-rail or wheel-shaft interface. A controller is configured to receive input from each of the sensors and activate the at least one actuator and/or motors, to generate or adjust regulated compressive force and associated tractive force delivered at the wheel-rail interface and/or the wheel-shaft interface.

Abstract: The disclosure provides gene therapy compositions and methods for treating galactosemia (e.g., classic galactosemia). In particular, the disclosure provides compositions comprising recombinant adeno-associated viruses (rAAVs) comprising an AAV capsid protein, and an AAV expression cassette encoding Galactose-1-Phosphate Uridylyltransferase (GALT), and methods of use thereof.

Abstract: In some embodiments, a method of machine learning includes identifying, by an auto encoder network, a simulator feature based, at least in part, on a received first simulator data set and an emulator feature based, at least in part, on a received first emulator data set. The method further includes determining, by a synthesis control circuitry, a synthesized feature based, at least in part, on the simulator feature and based, at least in part, on the emulator feature; and generating, by the auto encoder network, an intermediate data set based, at least in part, on a second simulator data set and including the synthesized feature. Some embodiments of the method further include determining, by a generative artificial neural network, a synthesized data set based, at least in part, on the intermediate data set and based, at least in part, on an objective function.

Abstract: Techniques for assessing an operational condition of an uncrewed air transport platform are presented. The techniques include: arranging the uncrewed air transport platform and at least one external sensor in proximity to each other, where the at least one external sensor includes a vibration sensor; executing a sequence of operations of the uncrewed air transport platform; acquiring sensor data of the uncrewed air transport platform from the at least one external sensor; automatically analyzing the sensor data to detect at least one non-normal health signature of the uncrewed air transport platform; automatically diagnosing one or more degradation condition in the uncrewed air transport platform based on the at least one non-normal health signature; and providing an indication of the one or more degradation condition.

Abstract: A method of using a processing computer comprising a memory comprising a hash index table and an array index table is disclosed. The method includes receiving an initial request message comprising a plurality of data fields with data elements for a transaction, and creating service request messages, where each service request message comprises a transaction key and data elements. The method includes transmitting the service request messages to server computers, which process them and generate service response messages, each service response message having the transaction key and response data. The method includes receiving the service response messages. The method includes for each of the service response messages: accessing the hash index table and determining a row address identifier for a row in the array index table based on the transaction key, and accessing data in the row of the array index table associated with the row address identifier.

Abstract: A data store system may include a storage device configured to store a plurality of data store tables and may include a processor in communication with the storage device. The processor may receive a plurality of requests. For each request, the processor may: (1) determine an associated workload type for the request; (2) determine a first respective rate at which the request is to be released for scheduling of execution; and (3) release the request for scheduling of execution based on the first respective rate. For each released request, the processor may: (1) determine a second respective rate based on the associated workload type at which each released request is scheduled to be executed; and (2) in response to execution being scheduled for a released request, execute the released request. A method and computer-readable medium are also disclosed.

Abstract: Described herein are systems and methods for real-time fault detection in electrical circuits. Various embodiments provide a fault detection circuit that uses a resistor network that is controlled to detect an internal current leak in multiple directions, e.g., to ground or to a power supply. The magnitude of the leakage current may be estimated from voltage measurements at voltage pins. In addition, as part of circuit diagnostics, open and short circuit fault conditions may be identified by using current sources and measuring deflections at the voltage pins.

Abstract: A system and method of detecting display fit measurements and/or ophthalmic measurements for a head mounted wearable computing device including a display device is provided. The system and method may include capturing image data including a face of a user to be fitted for the head mounted wearable computing device. A three-dimensional head pose and gaze measurements may be extracted and a three-dimensional model may be developed from the captured image data. The system may detect display fit measurements and/or ophthalmic fit measurements from the three-dimensional model, and may provide one or more head mounted wearable computing devices that meet the display fit and/or ophthalmic fit requirements.

Abstract: A method of distributing alerts based on received internet of things device information includes: receiving, by the alert routing system, first information from a first internet of things device relating to a first condition monitored by the first internet of things device, determining, by the alert routing system, that the first information corresponds to a first alert condition, generating, by the alert routing system, a listing of alert conditions, where the listing of alert conditions includes the first alert condition, receiving, by the alert routing system, second information from a second internet of things device relating to a second condition monitored by the second internet of things device, determining, by the alert routing system, that the second information corresponds to a second alert condition; and adding, by the alert routing system, the second alert condition to the listing of alert conditions.