Patents by Inventor Daniel de Roulet

Daniel de Roulet has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and Methods of Using the Same for Treatment of Neurodegenerative and Mitochondrial Disease
    Publication number: 20220274989
    Abstract: The disclosure is directed to compounds and pharmaceutically acceptable salts thereof for the treatment and/or prevention of neurodegenerative and/or mitochondrial diseases, such as Parkinson's disease and Leigh's disease. The compounds and pharmaceutically acceptable salts thereof are of the class of nitrogenous bases, for example, pyrimidines, purines, pteridines, and pharmaceutically acceptable salts thereof.
    Type: Application
    Filed: October 5, 2020
    Publication date: September 1, 2022
    Applicant: Mitokinin, Inc.
    Inventors: Daniel de Roulet, Robert Devita
  • Substituted purines for the treatment of neurodegenerative and mitochondrial diseases
    Patent number: 11414419
    Abstract: The present disclosure is directed, in part, to substituted purines, or pharmaceutically acceptable salts thereof, represented by formula (VIII): for the treatment and/or prevention of neurodegenerative disease, mitochondrial disease, fibrosis, and/or cardiomyopathy.
    Type: Grant
    Filed: June 21, 2018
    Date of Patent: August 16, 2022
    Assignee: MITOKININ, INC.
    Inventors: Daniel de Roulet, Robert Devita
  • COMPOSITIONS AND METHODS OF USING THE SAME FOR TREATMENT OF NEURODEGENERATIVE AND MITOCHONDRIAL DISEASE
    Publication number: 20220162215
    Abstract: The present disclosure is directed to nitrogen-containing heteroaryl analogs, methods of making nitrogen-containing analogs, and methods of treating disorders associated with PINK1 kinase activity including, but not limited to, neurodegenerative diseases, mitochondrial diseases, fibrosis, and/or cardiomyopathy using these analogs. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: April 3, 2020
    Publication date: May 26, 2022
    Inventors: Daniel de Roulet, Johan Bartholomeus, Shawn Johnstone, Randall Marcelo Chin, Nicholas Thomas Hertz, Robert DeVita
  • Compositions and Methods of Using the Same for Treatment of Neurodegenerative and Mitochondrial Disease
    Publication number: 20210107910
    Abstract: The disclosure is directed to compounds and pharmaceutically acceptable salts thereof for the treatment and/or prevention of neurodegenerative and/or mitochondrial diseases, such as Parkinson's disease and Leigh's disease. The compounds and pharmaceutically acceptable salts thereof are of the class of nitrogenous bases, for example, pyrimidines, purines, pteridines, and pharmaceutically acceptable salts thereof.
    Type: Application
    Filed: October 5, 2020
    Publication date: April 15, 2021
    Applicant: Mitokinin, Inc.
    Inventors: Daniel de Roulet, Robert Devita
  • Compositions and methods of using the same for treatment of neurodegenerative and mitochondrial disease
    Patent number: 10851109
    Abstract: The disclosure is directed to compounds and pharmaceutically acceptable salts thereof for the treatment and/or prevention of neurodegenerative and/or mitochondrial diseases, such as Parkinson's disease and Leigh's disease. The compounds and pharmaceutically acceptable salts thereof are of the class of nitrogenous bases, for example, pyrimidines, purines, pteridines, and pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: November 15, 2018
    Date of Patent: December 1, 2020
    Assignee: Mitokinin LLC
    Inventors: Daniel de Roulet, Robert Devita
  • COMPOSITIONS AND METHODS OF USING THE SAME FOR TREATMENT OF NEURODEGENERATIVE AND MITOCHONDRIAL DISEASE
    Publication number: 20200223851
    Abstract: The present disclosure is directed, in part, to compounds, or pharmaceutically acceptable salts thereof, for the treatment and/or prevention of neurodegenerative disease, mitchonodrial disease, fibrosis, and/or cardiomyopathy.
    Type: Application
    Filed: June 21, 2018
    Publication date: July 16, 2020
    Inventors: Daniel de Roulet, Robert Devita
  • COMPOSITIONS AND METHODS OF USING THE SAME FOR TREATMENT OF NEURODEGENERATIVE AND MITOCHONDRIAL DISEASE
    Publication number: 20190194207
    Abstract: The present disclosure is directed, in part, to compounds, or pharmaceutically acceptable salts thereof, for the treatment and/or prevention of neurodegenerative disease, mitochondrial disease, fibrosis, and/or cardiomyopathy.
    Type: Application
    Filed: November 15, 2018
    Publication date: June 27, 2019
    Inventors: Daniel de Roulet, Robert Devita
  • Compositions and methods using the same for treatment of neurodegenerative and mitochondrial disease
    Patent number: 10167286
    Abstract: The disclosure is directed to compounds and pharmaceutically acceptable salts thereof for the treatment and/or prevention of neurodegenerative and/or mitochondrial diseases, such as Parkinson's disease and Leigh's disease. The compounds and pharmaceutically acceptable salts thereof are of the class of nitrogenous bases, for example, pyrimidines, purines, pteridines and pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: February 11, 2015
    Date of Patent: January 1, 2019
    Assignee: Mitokinin, Inc.
    Inventors: Daniel de Roulet, Robert Devita
  • COMPOSITIONS AND METHODS USING THE SAME FOR TREATMENT OF NEURODEGENERATIVE AND MITOCHONDRIAL DISEASE
    Publication number: 20170190704
    Abstract: The present disclosure is directed, in part, to compounds, or pharmaceutically acceptable salts thereof, for the treatment and/or prevention of neurodegenerative disease and/or mitchonodrial disease including Parkinson's disease and Leigh's disease.
    Type: Application
    Filed: February 11, 2015
    Publication date: July 6, 2017
    Applicant: Mitokinin, LLC
    Inventors: Daniel de Roulet, Robert Devita