Abstract: A portable, modular handheld imaging system is disclosed. The modular system comprises a first housing portion and a second housing portion. The first housing portion includes at least one excitation light source. A first filter is configured to detect and permit passage of selected optical signals responsive to illumination with the excitation light to a first image sensor. A second filter is configured to detect and permit passage of selected optical signals responsive to illumination of the target surface with white light to a second image sensor. The second housing portion is configured to releasably receive the first housing portion. The second housing portion includes a display and a processor configured to receive the detected fluorescent and white light optical signals and to output a representation of the target surface to the display based on the detected optical signals.

Abstract: The present disclosure provides methods, systems, and devices for coregistering imaging data to form three-dimensional superimposed images of a biological target such as a wound, a tumor, or a surgical bed. A three-dimensional map can be generated by projecting infrared radiation at a target area, receiving reflected infrared radiation, and measuring depth of the target area. A three-dimensional white light image can be created from a captured two-dimensional white light image and the three-dimensional map. A three-dimensional fluorescence image can be created from a captured two-dimensional fluorescence image and the three-dimensional map. The three-dimensional white light image and the three-dimensional fluorescence image can be aligned using one or more fiducial markers to form a three-dimensional superimposed image. The superimposed image can be used to track wound healing and to excise cancerous tissues, for example, breast tumors. Images can be in the form of videos.

Abstract: A door monitoring system included a braking system. The present disclosure may include a position sensor that determines a position of a door; a position filter in series with the position sensor to generate a position signal; a speed filter to generate a speed signal from the position signal; an anticipation circuit to determine an anticipated position of the door at a future period based on the position signal and the speed signal; determine, based on the anticipated position, an anticipated speed; and determine whether the anticipated speed exceeds an allowable speed and engage a relay configured to disconnect a drive circuit and connect at least one braking resistor to a motor to slow the speed of the door. In some aspects, the braking system comprises at least one controller for performing one or more of the above steps.

Abstract: The present disclosure provides methods, systems, and devices for coregistering imaging data to form three-dimensional superimposed images of a biological target such as a wound, a tumor, or a surgical bed. A three-dimensional map can be generated by projecting infrared radiation at a target area, receiving reflected infrared radiation, and measuring depth of the target area. A three-dimensional white light image can be created from a captured two-dimensional white light image and the three-dimensional map. A three-dimensional fluorescence image can be created from a captured two-dimensional fluorescence image and the three-dimensional map. The three-dimensional white light image and the three-dimensional fluorescence image can be aligned using one or more fiducial markers to form a three-dimensional superimposed image. The superimposed image can be used to track wound healing and to excise cancerous tissues, for example, breast tumors. Images can be in the form of videos.

Abstract: Systems, devices, and methods for thermal imaging of a wound are provided. A multi-modal imaging device is configured to capture fluorescence images and thermal images of a target such as a wound. The device is further configured to determine a temperature differential between two user-selected regions of one or more of the captured images and provide an output indicative of the temperature differential. The output display also includes the fluorescence image.

Abstract: The present disclosure provides methods, systems, and devices for coregistering imaging data to form three-dimensional superimposed images of a biological target such as a wound, a tumor, or a surgical bed. A three-dimensional map can be generated by projecting infrared radiation at a target area, receiving reflected infrared radiation, and measuring depth of the target area. A three-dimensional white light image can be created from a captured two-dimensional white light image and the three-dimensional map. A three-dimensional fluorescence image can be created from a captured two-dimensional fluorescence image and the three-dimensional map. The three-dimensional white light image and the three-dimensional fluorescence image can be aligned using one or more fiducial markers to form a three-dimensional superimposed image. The superimposed image can be used to track wound healing and to excise cancerous tissues, for example, breast tumors. Images can be in the form of videos.

Abstract: A portable, modular handheld imaging system is disclosed. The modular system comprises a first housing portion and a second housing portion. The first housing portion includes at least one excitation light source. A first filter is configured to detect and permit passage of selected optical signals responsive to illumination with the excitation light to a first image sensor. A second filter is configured to detect and permit passage of selected optical signals responsive to illumination of the target surface with white light to a second image sensor. The second housing portion is configured to releasably receive the first housing portion. The second housing portion includes a display and a processor configured to receive the detected fluorescent and white light optical signals and to output a representation of the target surface to the display based on the detected optical signals.

Abstract: A drape for use with fluorescence-based imaging and white-light imaging includes a drape body. The drape body is configured to limit passage of electromagnetic radiation including light through the drape body to an interior imaging environment defined by the drape body such that electromagnetic radiation including ambient light within the interior imaging environment does not exceed a predetermined threshold. The drape also includes a connecting element permanently coupled to the drape body. The connecting element defines a hole in the drape body. The connecting element is configured to attach the drape to a portable, handheld imaging device.

Abstract: A sample handling apparatus/technique/method for a material analyze including a sample carrier for presenting a pressurized sample (e.g., LPG) to a sample focal area of the analyzer; a removable fixture for charging the pressurized sample into the sample carrier; the removable fixture including at least one port to provide sample to and from the fixture and carrier. The sample handling apparatus may include a retainer, wherein the sample carrier is removeably combined with the fixture using the retainer, the apparatus being insertable into the analyzer for sample analysis; and wherein the retainer includes an aperture for presenting the sample to the focal area from a filmed, lower end of the carrier in proximity therewith.

Abstract: A sample handling apparatus/technique/method for a material analyze including a sample carrier for presenting a pressurized sample (e.g., LPG) to a sample focal area of the analyzer; a removable fixture for charging the pressurized sample into the sample carrier; the removable fixture including at least one port to provide sample to and from the fixture and carrier. The sample handling apparatus may include a retainer, wherein the sample carrier is removeably combined with the fixture using the retainer, the apparatus being insertable into the analyzer for sample analysis; and wherein the retainer includes an aperture for presenting the sample to the focal area from a filmed, lower end of the carrier in proximity therewith.

Abstract: A handheld x-ray analyzer, having an outer shell forming an inner cavity, the outer shell having at least one aperture; an x-ray engine positioned within the cavity; and a generally planar heat sink rigidly and thermally attached to the x-ray engine, and positioned in the aperture of the outer shell thereby substantially filling the aperture while providing thermal conduction between the engine and surrounding air. An outer face of the heat sink may be substantially conformal with the outer shell along one or both sides of the analyzer, and form a substantial portion of one or both sides of the analyzer. Longitudinal fins may be placed on an outer face of the heat sink to aid in thermal conduction from the engine to the surrounding air. Thermal handling, shock/vibration isolation, and moisture barriers are provided.

Abstract: A handheld x-ray analyzer, having an outer shell forming an inner cavity, the outer shell having at least one aperture; an x-ray engine positioned within the cavity; and a generally planar heat sink rigidly and thermally attached to the x-ray engine, and positioned in the aperture of the outer shell thereby substantially filling the aperture while providing thermal conduction between the engine and surrounding air. An outer face of the heat sink may be substantially conformal with the outer shell along one or both sides of the analyzer, and form a substantial portion of one or both sides of the analyzer. Longitudinal fins may be placed on an outer face of the heat sink to aid in thermal conduction from the engine to the surrounding air. Thermal handling, shock/vibration isolation, and moisture barriers are provided.