Abstract: In an embodiment, a method includes receiving user-behavior data for a plurality of software applications. The method also includes determining activity windows for the plurality of software applications. The method also includes generating a time map of the activity windows. The method also includes detecting a usage pattern, where the usage pattern indicates two or more applications of the plurality of software applications that are used in combination. The method also includes identifying a user-centric workload from the usage pattern. The method also includes generating a user-centric workload specification for the user-centric workload, where the user-centric workload identifies the two or more applications indicated by the usage pattern. The method also includes associating the user-centric workload specification with an optimization trigger and an optimization profile. The method also includes optimizing the user-centric workload in accordance with the optimization trigger and the optimization profile.

Abstract: An improved method for orally administering buspirone to a human subject wherein the bioavailability of buspirone is increased and its elimination, metabolite formation, and variability of these pharmacokinetic parameters is decreased, the improvement comprises the concurrent administration of a sufficient amount of nefazodone to effect these pharmacokinetic changes for orally administered buspirone.