Patents by Inventor Daniel ELBRECHT

Daniel ELBRECHT has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pumpless microfluidic organ-on-a-chip system including a functional immune system
    Patent number: 11554373
    Abstract: A pumpless microfluidic system is disclosed that can be used to mimic the interaction of organ systems with the immune system. Also disclosed is a method for mimicking an immune system, comprising culturing a plurality of organ cells and at least one population of immune cells in the disclosed pumpless microfluidic system under physiological conditions. The method can further comprise activating an immune reaction in the pumpless microfluidic system, continuing the culture for a defined period, collecting a sample of culture medium from the system, and assaying the sample for one or more indicators of an immune response.
    Type: Grant
    Filed: December 29, 2017
    Date of Patent: January 17, 2023
    Assignees: University of Central Florida Research Foundation, Inc., Hesperos, Inc.
    Inventors: James Hickman, Alisha Colon, Christopher McAleer, Trevor Sasserath, John Rumsey, Daniel Elbrecht
  • PUMPLESS MICROFLUIDIC ORGAN-ON-A-CHIP SYSTEM INCLUDING A FUNCTIONAL IMMUNE SYSTEM
    Publication number: 20200001297
    Abstract: A pumpless microfluidic system is disclosed that can be used to mimic the interaction of organ systems with the immune system. Also disclosed is a method for mimicking an immune system, comprising culturing a plurality of organ cells and at least one population of immune cells in the disclosed pumpless microfluidic system under physiological conditions. The method can further comprise activating an immune reaction in the pumpless microfluidic system, continuing the culture for a defined period, collecting a sample of culture medium from the system, and assaying the sample for one or more indicators of an immune response.
    Type: Application
    Filed: December 29, 2017
    Publication date: January 2, 2020
    Inventors: James HICKMAN, Alisha COLON, Christopher MCALEER, Trevor SASSERATH, John RUMSEY, Daniel ELBRECHT