Abstract: The invention refers to a bottom dispensing package for a flowable composition, comprising a squeezable container for housing the flowable composition, a base element that is fixed to the container, whereby the base element comprises an orifice, whereby the orifice is placed in the direction of gravity beneath the container when the dispensing package is placed in its head-stand position on the base element, whereby the base element further comprises a closure connected to the base element and the closure can be moved back and forth between a closed position in which the closure closes the orifice and an open position in which the composition can be released through the orifice.

Abstract: The present invention relates to a closure for a container with a base element and a flip-top lid attached to said base element by a hinge. The flip-top lid can be moved between an opened and a closed position. The base element has a skirt with attachment means for attaching the closure to the container, and said flip-top lid has a top cover and a sidewall. The closure comprises an actuating region with a latching element, wherein said actuating region is tiltable and/or deformable relative to the remaining regions of the sidewall between a latching position and a released position. The present invention also relates to a container with such a closure.

Abstract: The present invention relates to a closure device (1) for a container (2) in which a flowable material (3) is stored, including a base element (4), which can be fastened on a container opening (5) of the container (2), a spout (11) with a dispensing opening (7), whereby the spout (11) is positioned inboard of the base element (4), and a lid (8) connected to the base element (4) by a hinge (12), whereby the lid (8) can be moved back and forth between a closed position (9) so that the spout (11) is not accessible and an open position (10) in which the spout (11) is accessible, tamper evidence indication structures (13) for visually indicating if the lid (8) of closure device (1) has once been moved out of its closed position (9).

Abstract: The present invention relates to a closure device (1) for a container (2) in which a flowable material (3) is stored, comprising a base element (4), which can be fastened on a container opening (5) of the container (2), a spout (11) with a dispensing opening (7), whereby the spout (11) is positioned inboard of the base element (4), and a lid (8) connected to the base element (4) by a hinge (12), whereby the lid (8) can be moved back and forth between a closed position (9) in which the lid (8) closes the dispensing opening (7) so that the spout (11) is not accessible and an open position (10) in which the spout (11) is accessible, tamper evidence indication means (13) for visually indicating if the lid (8) of the closure device (1) has once been moved out of its closed position (9), whereby the tamper evidence indication means (13) comprise a first indication ring (14) and at least a second indication ring (15) which is co-axially arranged in the first indication ring (14).

Abstract: The present invention relates to a closure device (1) for a container (2) in which a flowable material (3) is stored, comprising a base element (4), which can be fastened on a container opening (5) of the container (2), a spout (11) with a dispensing opening (7), whereby the spout (11) is positioned inboard of the base element (4), and a lid (8) connected to the base element (4) by a hinge (12), whereby the lid (8) can be moved back and forth between a closed position (9) in which the lid (8) closes the dispensing opening (7) so that the spout (11) is not accessible and an open position (10) in which the spout (11) is accessible, tamper evidence indication means (13) for visually indicating if the lid (8) of the closure device (1) has once been moved out of its closed position (9).

Abstract: The invention refers to a bottom dispensing package for a flowable composition, comprising a squeezable container for housing the flowable composition, a base element that is fixed to the container, whereby the base element comprises an orifice, whereby the orifice is placed in the direction of gravity beneath the container when the dispensing package is placed in its head-stand position on the base element, whereby the base element further comprises a closure connected to the base element and the closure can be moved back and forth between a closed position in which the closure closes the orifice and an open position in which the composition can be released through the orifice.

Abstract: The present invention relates to a closure for a container with a base element (100), a flip-top lid (200) attached to said base element (100) by a hinge (150) such that the flip-top lid (200) can be moved between an opened and a closed position, and with a tamper evident unit (400) for indicating whether the flip-top lid (200) had been opened at least once by a user or not. Said tamper evident unit (400) comprising a first tamper evident element (420) and a second tamper evident element (440), which are, when said closure is in its as-manufactured status or when said flip-top lid (200) has not been opened yet by the user, connected to each other by at least one frangible bridge (430).

Abstract: The present invention relates to a closure device (1) for a container (2) in which a flowable material (3) is stored, comprising a base element (4), which can be fastened on a container opening (5) of the container (2), a spout (11) with a dispensing opening (7), whereby the spout (11) is positioned inboard of the base element (4), and a lid (8) connected to the base element (4) by a hinge (12), whereby the lid (8) can be moved back and forth between a closed position (9) in which the lid (8) closes the dispensing opening (7) so that the spout (11) is not accessible and an open position (10) in which the spout (11) is accessible, tamper evidence indication means (13) for visually indicating if the lid (8) of the closure device (1) has once been moved out of its closed position (9), whereby the tamper evidence indication means (13) comprise a first indication ring (14) and at least a second indication ring (15) which is co-axially arranged in the first indication ring (14).

Abstract: The present invention relates to a closure device (1) for a container (2) in which a flowable material (3) is stored, comprising a base element (4), which can be fastened on a container opening (5) of the container (2), a spout (11) with a dispensing opening (7), whereby the spout (11) is positioned inboard of the base element (4), and a lid (8) connected to the base element (4) by a hinge (12), whereby the lid (8) can be moved back and forth between a closed position (9) so that the spout (11) is not accessible and an open position (10) in which the spout (11) is accessible, tamper evidence indication means (13) for visually indicating if the lid (8) of closure device (1) has once been moved out of its closed position (9).

Abstract: The present invention relates to a closure device (1) for a container (2) in which a flowable material (3) is stored, comprising a base element (4), which can be fastened on a container opening (5) of the container (2), a spout (11) with a dispensing opening (7), whereby the spout (11) is positioned inboard of the base element (4), and a lid (8) connected to the base element (4) by a hinge (12), whereby the lid (8) can be moved back and forth between a closed position (9) in which the lid (8) closes the dispensing opening (7) so that the spout (11) is not accessible and an open position (10) in which the spout (11) is accessible, tamper evidence indication means (13) for visually indicating if the lid (8) of the closure device (1) has once been moved out of its closed position (9).

Abstract: The present invention relates to a process for manufacturing a closure device (1) for a container (2) in which a flowable material (3) is stored whereby the manufacturing process includes the following steps: moulding of the base element (4), the lid (8) and the hinge (12) with the lid (8) being moulded in its open position; closing of the lid (8) to the base element (4); moulding of the tamper evidence indication means (13), whereby the tamper evidence indication means (13) comprising a first indication ring (14) and a second indication ring (15) being coaxially positioned to each other and which are connected by at least one radially oriented frangible bridge (6); assembly of the tamper evidence indication means (13) into the base element (4) and the lid (8); assembly of the spout (11) into the base element (4).

Abstract: The present invention relates to a closure for a container with a base element (100), a flip-top lid (200) attached to said base element (100) by a hinge (150) such that the flip-top lid (200) can be moved between an opened and a closed position, and with a tamper evident unit (400) for indicating whether the flip-top lid (200) had been opened at least once by a user or not. Said tamper evident unit (400) comprising a first tamper evident element (420) and a second tamper evident element (440), which are, when said closure is in its as-manufactured status or when said flip-top lid (200) has not been opened yet by the user, connected to each other by at least one frangible bridge (430).

Abstract: The present invention relates to a closure for a container with a base element and a flip-top lid attached to said base element by a hinge. The flip-top lid can be moved between an opened and a closed position. The base element has a skirt with attachment means for attaching the closure to the container, and said flip-top lid has a top cover and a sidewall. The closure comprises an actuating region with a latching element, wherein said actuating region is tiltable and/or deformable relative to the remaining regions of the sidewall between a latching position and a released position. The present invention also relates to a container with such a closure.

Abstract: Provided are electrochemical cells for hydrogen production and methods for hydrogen production. The electrochemical cell and methods use a mediator that may have a reversible redox potential lying outside the onset of the oxygen evolution reaction (OER) and the hydrogen evolution reaction (HER). Also, provided are systems for generating hydrogen and water from oxygen and generating water from oxygen and hydrogen.

Abstract: A steering shaft for a motor vehicle has an inner shaft, arranged in an outer shaft that is displaceable axially in the direction of an axis of rotation. The inner shaft includes axially running radial projections on its outer side. The outer shaft includes axially running grooves on its inner side, into which grooves the projections of the inner shaft engage in a positively locking manner in a direction of rotation and displaceably in an axial direction. With regard to fault-free operation during fluctuating temperatures, on the inner shaft, there is arranged a profiled sleeve with undulating cross-sectional profile, the inner surface of which lies against the flanks of the projections of the inner shaft and the outer surfaces of which lie against the flanks of the grooves of the outer shaft, wherein the profiled sleeve is connected to the inner shaft at one or more fastening points.

Abstract: The invention relates to a pharmaceutical product comprising an allergen extract or an allergoid thereof for the treatment and/or prevention of allergy and allergic asthma caused by house dust mites, which extract comprises at least one extract of mite bodies selected from the following groups a)-b): a) An extract of Der p mite bodies, and b) An extract of Der f mite bodies, and at least one extract of mite cultures selected from the following groups c)-g): c) An extract of Der p faecal particles, d) An extract of Der f faecal particles, e) An extract of Der f whole mite culture, f) An extract of an Der p whole mite culture, and g) a combination of extracts c) to f).

Abstract: The invention relates to a pharmaceutical product comprising an allergen extract or an allergoid thereof for the treatment and/or prevention of allergy and allergic asthma caused by house dust mites, which extract comprises at least one extract of mite bodies selected from the following groups a)-b): a) An extract of Der p mite bodies, and b) An extract of Der f mite bodies, and at least one extract of mite cultures selected from the following groups c)-g): c) An extract of Der p faecal particles, d) An extract of Der f faecal particles, e) An extract of Der f whole mite culture, f) An extract of an Der p whole mite culture, and g) a combination of extracts c) to f).

Abstract: Provided are electrochemical cells for hydrogen production and methods for hydrogen production. The electrochemical cell and methods use a mediator that may have a reversible redox potential lying outside the onset of the oxygen evolution reaction (OER) and the hydrogen evolution reaction (HER). Also, provided are systems for generating hydrogen and water from oxygen and generating water from oxygen and hydrogen.

Abstract: The present invention relates to a process for taking up one or more nitrogen oxide(s) from a gaseous and/or aerosol or liquid medium using at least one particulate earth alkali carbonate-comprising material and/or at least one particulate earth alkali phosphate-comprising material as well as an adsorbing material comprising said at least one particulate earth alkali carbonate-comprising material and/or at least one particulate earth alkali phosphate-comprising material.

Abstract: The invention relates to a pharmaceutical product comprising an allergen extract or an allergoid thereof for the treatment and/or prevention of allergy and allergic asthma caused by house dust mites, which extract comprises at least one extract of mite bodies selected from the following groups a)-b): a) An extract of Der p mite bodies, and b) An extract of Der f mite bodies, and at least one extract of mite cultures selected from the following groups c)-g): c) An extract of Der p faecal particles, d) An extract of Der f faecal particles, e) An extract of Der f whole mite culture, f) An extract of an Der p whole mite culture, and g) a combination of extracts c) to f).